abolished Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

240 genes co-occuring with the biological term abolished in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABI2 abl-interactor 2
ACHE acetylcholinesterase (Yt blood group)
ADRA2B adrenoceptor alpha 2B
AGTR1 angiotensin II receptor, type 1
AIRE autoimmune regulator
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANG angiogenin, ribonuclease, RNase A family, 5
ANO7 anoctamin 7
ANXA1 annexin A1
APOA1 apolipoprotein A-I
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APP amyloid beta (A4) precursor protein
ARF6 ADP-ribosylation factor 6
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ASMT acetylserotonin O-methyltransferase
ATR ATR serine/threonine kinase
AXL AXL receptor tyrosine kinase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BACE1 beta-site APP-cleaving enzyme 1
BAG1 BCL2-associated athanogene
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BRCA1 breast cancer 1, early onset
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CASR calcium-sensing receptor
CCND1 cyclin D1
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD44 CD44 molecule (Indian blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHEK1 checkpoint kinase 1
COBL cordon-bleu WH2 repeat protein
COL8A2 collagen, type VIII, alpha 2
COL9A1 collagen, type IX, alpha 1
CPD carboxypeptidase D
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTGF connective tissue growth factor
CTSD cathepsin D
CUL4A cullin 4A
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAXX death-domain associated protein
DCK deoxycytidine kinase
DDB1 damage-specific DNA binding protein 1, 127kDa
DPP3 dipeptidyl-peptidase 3
DYNLL1 dynein, light chain, LC8-type 1
EPO erythropoietin
ESD esterase D
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F10 coagulation factor X
F11 coagulation factor XI
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FANCD2 Fanconi anemia, complementation group D2
FASN fatty acid synthase
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FGF2 fibroblast growth factor 2 (basic)
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXP3 forkhead box P3
FZD6 frizzled class receptor 6
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GCG glucagon
GHRL ghrelin/obestatin prepropeptide
GLUD1 glutamate dehydrogenase 1
GNRHR gonadotropin-releasing hormone receptor
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST3H3 histone cluster 3, H3
HJURP Holliday junction recognition protein
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HUS1 HUS1 checkpoint homolog (S. pombe)
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFI35 interferon-induced protein 35
IFNA2 interferon, alpha 2
IFNL1 interferon, lambda 1
IFNL2 interferon, lambda 2
IL10 interleukin 10
IL15 interleukin 15
IL19 interleukin 19
IL2 interleukin 2
IL4 interleukin 4
IL6 interleukin 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JUN jun proto-oncogene
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT15 keratin 15, type I
LAT2 linker for activation of T cells family, member 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LHCGR luteinizing hormone/choriogonadotropin receptor
LIFR leukemia inhibitory factor receptor alpha
LIPA lipase A, lysosomal acid, cholesterol esterase
LNPEP leucyl/cystinyl aminopeptidase
LPAR5 lysophosphatidic acid receptor 5
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LY96 lymphocyte antigen 96
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MATN3 matrilin 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEF2D myocyte enhancer factor 2D
MIF4GD MIF4G domain containing
MIR143 microRNA 143
MIR27A microRNA 27a
MIR329-1 microRNA 329-1
MIR410 microRNA 410
MLH1 mutL homolog 1
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MSRB3 methionine sulfoxide reductase B3
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MX1 MX dynamin-like GTPase 1
MYD88 myeloid differentiation primary response 88
NBN nibrin
NEU3 sialidase 3 (membrane sialidase)
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX1 NADPH oxidase 1
NR2C2 nuclear receptor subfamily 2, group C, member 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OCLN occludin
OR2J3 olfactory receptor, family 2, subfamily J, member 3
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAH phenylalanine hydroxylase
PARK7 parkinson protein 7
PAX6 paired box 6
PCNA proliferating cell nuclear antigen
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRL prolactin
PRLR prolactin receptor
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD1 RAD1 checkpoint DNA exonuclease
RASD1 RAS, dexamethasone-induced 1
RB1 retinoblastoma 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCC2 regulator of chromosome condensation 2
RFX1 regulatory factor X, 1 (influences HLA class II expression)
RGS2 regulator of G-protein signaling 2
RHOA ras homolog family member A
RMRP RNA component of mitochondrial RNA processing endoribonuclease
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX2 runt-related transcription factor 2
RYR2 ryanodine receptor 2 (cardiac)
SCN5A sodium channel, voltage gated, type V alpha subunit
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SGMS1 sphingomyelin synthase 1
SGMS2 sphingomyelin synthase 2
SH2D1A SH2 domain containing 1A
SIRT1 sirtuin 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLURP1 secreted LY6/PLAUR domain containing 1
SMAD4 SMAD family member 4
SMN1 survival of motor neuron 1, telomeric
SOCS1 suppressor of cytokine signaling 1
SOX6 SRY (sex determining region Y)-box 6
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPHK1 sphingosine kinase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STC1 stanniocalcin 1
STS steroid sulfatase (microsomal), isozyme S
SULF2 sulfatase 2
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TFAM transcription factor A, mitochondrial
TGFB1 transforming growth factor, beta 1
THAP1 THAP domain containing, apoptosis associated protein 1
TICAM2 toll-like receptor adaptor molecule 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLR2 toll-like receptor 2
TLR5 toll-like receptor 5
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TOR1A torsin family 1, member A (torsin A)
TP53 tumor protein p53
TP63 tumor protein p63
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM11 tripartite motif containing 11
TRIM22 tripartite motif containing 22
TRIM28 tripartite motif containing 28
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TUBB3 tubulin, beta 3 class III
VANGL1 VANGL planar cell polarity protein 1
VEGFA vascular endothelial growth factor A
VPRBP Vpr (HIV-1) binding protein
VWF von Willebrand factor
WRN Werner syndrome, RecQ helicase-like
XPA xeroderma pigmentosum, complementation group A
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB7A zinc finger and BTB domain containing 7A