absent t cells Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the lymphocytes that are responsible for cell-mediated immunity and immune system regulation (Mammalian Phenotype Ontology, MP_0008070)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008070
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22 gene mutations causing the absent t cells phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
CD247 CD247 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
DCLRE1C DNA cross-link repair 1C
FOXN1 forkhead box N1
FOXP3 forkhead box P3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL17A interleukin 17A
IL17F interleukin 17F
IL2RG interleukin 2 receptor, gamma
IL7R interleukin 7 receptor
ITPKB inositol-trisphosphate 3-kinase B
LAT linker for activation of T cells
LYST lysosomal trafficking regulator
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTPRC protein tyrosine phosphatase, receptor type, C
RAG1 recombination activating gene 1
SH2D1A SH2 domain containing 1A
TBX21 T-box 21
TCF12 transcription factor 12
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa