acacetin-2189 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the acacetin-2189 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
AOC3 amine oxidase, copper containing 3
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APOLD1 apolipoprotein L domain containing 1
AVIL advillin
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BTBD18 BTB (POZ) domain containing 18
C21ORF2 chromosome 21 open reading frame 2
CBX5 chromobox homolog 5
CCDC71 coiled-coil domain containing 71
CCL20 chemokine (C-C motif) ligand 20
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKL3 cyclin-dependent kinase-like 3
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLEC4A C-type lectin domain family 4, member A
CLTA clathrin, light chain A
CORT cortistatin
CREM cAMP responsive element modulator
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DZIP3 DAZ interacting zinc finger protein 3
EFCAB6 EF-hand calcium binding domain 6
FAAH fatty acid amide hydrolase
FGD1 FYVE, RhoGEF and PH domain containing 1
FLOT1 flotillin 1
FLRT1 fibronectin leucine rich transmembrane protein 1
GAS8 growth arrest-specific 8
GCM1 glial cells missing homolog 1 (Drosophila)
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIP2 glutamate receptor interacting protein 2
HCRT hypocretin (orexin) neuropeptide precursor
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IGFALS insulin-like growth factor binding protein, acid labile subunit
ITGB5 integrin, beta 5
JMJD6 jumonji domain containing 6
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
KRCC1 lysine-rich coiled-coil 1
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LOC157562 uncharacterized LOC157562
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP25 matrix metallopeptidase 25
MOG myelin oligodendrocyte glycoprotein
MSH4 mutS homolog 4
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MYH15 myosin, heavy chain 15
N4BP2L2 NEDD4 binding protein 2-like 2
NEB nebulin
NR4A3 nuclear receptor subfamily 4, group A, member 3
NT5E 5'-nucleotidase, ecto (CD73)
OVGP1 oviductal glycoprotein 1, 120kDa
PAQR6 progestin and adipoQ receptor family member VI
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDE10A phosphodiesterase 10A
PDZK1 PDZ domain containing 1
PLD3 phospholipase D family, member 3
PLSCR3 phospholipid scramblase 3
PML promyelocytic leukemia
PRDM10 PR domain containing 10
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSKH1 protein serine kinase H1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
REC8 REC8 meiotic recombination protein
RFPL3S RFPL3 antisense
RNFT2 ring finger protein, transmembrane 2
RPL31 ribosomal protein L31
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RTCA RNA 3'-terminal phosphate cyclase
RUNDC3B RUN domain containing 3B
SCG5 secretogranin V
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMIM7 small integral membrane protein 7
SORBS3 sorbin and SH3 domain containing 3
SPG20 spastic paraplegia 20 (Troyer syndrome)
ST20 suppressor of tumorigenicity 20
STAB1 stabilin 1
SYTL2 synaptotagmin-like 2
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TF transferrin
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TP53I11 tumor protein p53 inducible protein 11
TPH1 tryptophan hydroxylase 1
ZBTB1 zinc finger and BTB domain containing 1
ZNF137P zinc finger protein 137, pseudogene

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ACPP acid phosphatase, prostate
ADAP2 ArfGAP with dual PH domains 2
ADCY7 adenylate cyclase 7
ADRB2 adrenoceptor beta 2, surface
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
ARHGAP10 Rho GTPase activating protein 10
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARRB1 arrestin, beta 1
ATP10D ATPase, class V, type 10D
BATF basic leucine zipper transcription factor, ATF-like
BBS7 Bardet-Biedl syndrome 7
BIK BCL2-interacting killer (apoptosis-inducing)
C17ORF70 chromosome 17 open reading frame 70
CAMKMT calmodulin-lysine N-methyltransferase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CBX7 chromobox homolog 7
CCDC69 coiled-coil domain containing 69
CCR2 chemokine (C-C motif) receptor 2
CD101 CD101 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD300C CD300c molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CX3CR1 chemokine (C-X3-C motif) receptor 1
DACH1 dachshund family transcription factor 1
DEPDC5 DEP domain containing 5
DEPTOR DEP domain containing MTOR-interacting protein
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
EMILIN2 elastin microfibril interfacer 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV4 ets variant 4
FAM102A family with sequence similarity 102, member A
FBXO46 F-box protein 46
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FUCA1 fucosidase, alpha-L- 1, tissue
GBAP1 glucosidase, beta, acid pseudogene 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GK3P glycerol kinase 3 pseudogene
GTF2IRD1 GTF2I repeat domain containing 1
GTPBP8 GTP-binding protein 8 (putative)
H1FX H1 histone family, member X
HDAC9 histone deacetylase 9
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HSPA4L heat shock 70kDa protein 4-like
IFT81 intraflagellar transport 81
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IRF8 interferon regulatory factor 8
ISOC1 isochorismatase domain containing 1
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LPAR6 lysophosphatidic acid receptor 6
LRMP lymphoid-restricted membrane protein
LXN latexin
LZTS3 leucine zipper, putative tumor suppressor family member 3
MSRB1 methionine sulfoxide reductase B1
MX2 MX dynamin-like GTPase 2
MYL12B myosin, light chain 12B, regulatory
NCF1C neutrophil cytosolic factor 1C pseudogene
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFE2 nuclear factor, erythroid 2
NIPAL2 NIPA-like domain containing 2
OCEL1 occludin/ELL domain containing 1
PARG poly (ADP-ribose) glycohydrolase
PDZD7 PDZ domain containing 7
PLA2G15 phospholipase A2, group XV
PLEKHA5 pleckstrin homology domain containing, family A member 5
POMT1 protein-O-mannosyltransferase 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTTG1 pituitary tumor-transforming 1
RAP1GAP2 RAP1 GTPase activating protein 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SP140L SP140 nuclear body protein-like
SPC25 SPC25, NDC80 kinetochore complex component
SPINT1 serine peptidase inhibitor, Kunitz type 1
SURF2 surfeit 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM7SF3 transmembrane 7 superfamily member 3
TMEM53 transmembrane protein 53
TRIM22 tripartite motif containing 22
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
TUBB2A tubulin, beta 2A class IIa
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TWISTNB TWIST neighbor
USB1 U6 snRNA biogenesis 1
VNN1 vanin 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZBED8 zinc finger, BED-type containing 8
ZC3H12A zinc finger CCCH-type containing 12A
ZC4H2 zinc finger, C4H2 domain containing
ZNF219 zinc finger protein 219
ZW10 zw10 kinetochore protein