acacetin-3849 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the acacetin-3849 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD2 abhydrolase domain containing 2
ACVR1B activin A receptor, type IB
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASIC1 acid sensing (proton gated) ion channel 1
ATN1 atrophin 1
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BMP8A bone morphogenetic protein 8a
C1ORF61 chromosome 1 open reading frame 61
C1QL1 complement component 1, q subcomponent-like 1
CDK16 cyclin-dependent kinase 16
CDK18 cyclin-dependent kinase 18
CELF3 CUGBP, Elav-like family member 3
CEP162 centrosomal protein 162kDa
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CTIF CBP80/20-dependent translation initiation factor
CUZD1 CUB and zona pellucida-like domains 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DNM3 dynamin 3
EML2 echinoderm microtubule associated protein like 2
EN2 engrailed homeobox 2
FADS2 fatty acid desaturase 2
FAM188A family with sequence similarity 188, member A
FAM212B family with sequence similarity 212, member B
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF8 fibroblast growth factor 8 (androgen-induced)
GLDC glycine dehydrogenase (decarboxylating)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
ICOSLG inducible T-cell co-stimulator ligand
IDS iduronate 2-sulfatase
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IFT27 intraflagellar transport 27
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL1RN interleukin 1 receptor antagonist
IRF8 interferon regulatory factor 8
IRS2 insulin receptor substrate 2
KHSRP KH-type splicing regulatory protein
KIAA0754 KIAA0754
KIFC1 kinesin family member C1
KLF13 Kruppel-like factor 13
KLK13 kallikrein-related peptidase 13
LATS1 large tumor suppressor kinase 1
LEFTY1 left-right determination factor 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK11 mitogen-activated protein kinase 11
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MYCNOS MYCN opposite strand
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NOL12 nucleolar protein 12
OXCT2 3-oxoacid CoA transferase 2
PER2 period circadian clock 2
PIGR polymeric immunoglobulin receptor
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKNOX1 PBX/knotted 1 homeobox 1
POFUT1 protein O-fucosyltransferase 1
PPARD peroxisome proliferator-activated receptor delta
PRMT2 protein arginine methyltransferase 2
PTH1R parathyroid hormone 1 receptor
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASAL2 RAS protein activator like 2
RBM38 RNA binding motif protein 38
RFPL1S RFPL1 antisense RNA 1
RPGR retinitis pigmentosa GTPase regulator
RPS3A ribosomal protein S3A
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SP1 Sp1 transcription factor
SPEG SPEG complex locus
SRCAP Snf2-related CREBBP activator protein
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRGN serglycin
SRRM2 serine/arginine repetitive matrix 2
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT4 signal transducer and activator of transcription 4
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TGFA transforming growth factor, alpha
THTPA thiamine triphosphatase
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAF4 TNF receptor-associated factor 4
TRPC4 transient receptor potential cation channel, subfamily C, member 4
YY2 YY2 transcription factor
ZFYVE9 zinc finger, FYVE domain containing 9
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ACTL8 actin-like 8
AKAP12 A kinase (PRKA) anchor protein 12
ALOX15 arachidonate 15-lipoxygenase
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARPIN actin-related protein 2/3 complex inhibitor
ARR3 arrestin 3, retinal (X-arrestin)
ARRB1 arrestin, beta 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAG4 BCL2-associated athanogene 4
BHLHE41 basic helix-loop-helix family, member e41
BIRC7 baculoviral IAP repeat containing 7
C11ORF21 chromosome 11 open reading frame 21
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
CALB2 calbindin 2
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD48 CD48 molecule
CDKL3 cyclin-dependent kinase-like 3
CHM choroideremia (Rab escort protein 1)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNGB3 cyclic nucleotide gated channel beta 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXADR coxsackie virus and adenovirus receptor
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DEFB126 defensin, beta 126
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EDC3 enhancer of mRNA decapping 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC5 excision repair cross-complementation group 5
ERN1 endoplasmic reticulum to nucleus signaling 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
GALK1 galactokinase 1
GPATCH2L G patch domain containing 2-like
GSTA4 glutathione S-transferase alpha 4
HIST1H1B histone cluster 1, H1b
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HIST1H4E histone cluster 1, H4e
HOXD11 homeobox D11
HPN hepsin
IFT54 intraflagellar transport 54
IL22 interleukin 22
INCENP inner centromere protein antigens 135/155kDa
LRP5L low density lipoprotein receptor-related protein 5-like
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MRPL52 mitochondrial ribosomal protein L52
MRPS18C mitochondrial ribosomal protein S18C
MTA2 metastasis associated 1 family, member 2
MTERF4 mitochondrial transcription termination factor 4
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MUC3A mucin 3A, cell surface associated
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NXPH4 neurexophilin 4
PACS1 phosphofurin acidic cluster sorting protein 1
PADI3 peptidyl arginine deiminase, type III
PARD6B par-6 family cell polarity regulator beta
PCDHB8 protocadherin beta 8
PLCD1 phospholipase C, delta 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PRAMEF11 PRAME family member 11
PTCD2 pentatricopeptide repeat domain 2
QSER1 glutamine and serine rich 1
RNF122 ring finger protein 122
RPL10L ribosomal protein L10-like
RUNDC3B RUN domain containing 3B
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SHARPIN SHANK-associated RH domain interactor
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SPRR1B small proline-rich protein 1B
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STARD5 StAR-related lipid transfer (START) domain containing 5
STARD8 StAR-related lipid transfer (START) domain containing 8
STIM1 stromal interaction molecule 1
TAOK1 TAO kinase 1
TBC1D19 TBC1 domain family, member 19
TDRD1 tudor domain containing 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFBR3 transforming growth factor, beta receptor III
TLR2 toll-like receptor 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TUBA3C tubulin, alpha 3c
UPK2 uroplakin 2
VASH1 vasohibin 1
VN1R1 vomeronasal 1 receptor 1
WDR4 WD repeat domain 4
WFDC2 WAP four-disulfide core domain 2
ZBTB44 zinc finger and BTB domain containing 44
ZFP37 ZFP37 zinc finger protein
ZNF141 zinc finger protein 141
ZNF446 zinc finger protein 446
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76
ZSCAN2 zinc finger and SCAN domain containing 2