acacetin-3942 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the acacetin-3942 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ADAM29 ADAM metallopeptidase domain 29
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
AIM2 absent in melanoma 2
ANGPTL2 angiopoietin-like 2
AP3B2 adaptor-related protein complex 3, beta 2 subunit
APOLD1 apolipoprotein L domain containing 1
ATG10 autophagy related 10
BST1 bone marrow stromal cell antigen 1
BTN3A1 butyrophilin, subfamily 3, member A1
C9ORF16 chromosome 9 open reading frame 16
CA9 carbonic anhydrase IX
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CARD14 caspase recruitment domain family, member 14
CCDC57 coiled-coil domain containing 57
CCL13 chemokine (C-C motif) ligand 13
CCL27 chemokine (C-C motif) ligand 27
CD209 CD209 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CEL carboxyl ester lipase
CFAP74 cilia and flagella associated protein 74
CLTA clathrin, light chain A
CNTD2 cyclin N-terminal domain containing 2
COL4A1 collagen, type IV, alpha 1
COL6A3 collagen, type VI, alpha 3
COL7A1 collagen, type VII, alpha 1
CSDC2 cold shock domain containing C2, RNA binding
CSHL1 chorionic somatomammotropin hormone-like 1
CTIF CBP80/20-dependent translation initiation factor
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
ELP6 elongator acetyltransferase complex subunit 6
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERCC2 excision repair cross-complementation group 2
ETV7 ets variant 7
FLNC filamin C, gamma
FRMPD1 FERM and PDZ domain containing 1
GIPR gastric inhibitory polypeptide receptor
GPR15 G protein-coupled receptor 15
GRK5 G protein-coupled receptor kinase 5
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HR hair growth associated
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
ICAM2 intercellular adhesion molecule 2
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGLJ3 immunoglobulin lambda joining 3
IL18 interleukin 18
IL36A interleukin 36, alpha
JMJD6 jumonji domain containing 6
KLK13 kallikrein-related peptidase 13
KSR1 kinase suppressor of ras 1
LOC440895 two pore channel 3 pseudogene
LRRC17 leucine rich repeat containing 17
LSP1 lymphocyte-specific protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MIER2 mesoderm induction early response 1, family member 2
MOGAT2 monoacylglycerol O-acyltransferase 2
MT1F metallothionein 1F
MTL5 metallothionein-like 5, testis-specific (tesmin)
MUC6 mucin 6, oligomeric mucus/gel-forming
MYBPC3 myosin binding protein C, cardiac
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
PHOX2A paired-like homeobox 2a
PLK3 polo-like kinase 3
POLL polymerase (DNA directed), lambda
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
RAB33A RAB33A, member RAS oncogene family
RBMS2 RNA binding motif, single stranded interacting protein 2
RGS11 regulator of G-protein signaling 11
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SPAG8 sperm associated antigen 8
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
TAAR2 trace amine associated receptor 2
TCF3 transcription factor 3
TGM2 transglutaminase 2
TIGD6 tigger transposable element derived 6
TMEM40 transmembrane protein 40
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNS2 tensin 2
TP63 tumor protein p63
TPSB2 tryptase beta 2 (gene/pseudogene)
TRAPPC9 trafficking protein particle complex 9
TRH thyrotropin-releasing hormone
TSC2 tuberous sclerosis 2
UCN urocortin
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
USP29 ubiquitin specific peptidase 29
VPRBP Vpr (HIV-1) binding protein
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABHD17B abhydrolase domain containing 17B
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ALS2CL ALS2 C-terminal like
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARRB1 arrestin, beta 1
B9D2 B9 protein domain 2
BBS7 Bardet-Biedl syndrome 7
BCL2L2 BCL2-like 2
BCO1 beta-carotene oxygenase 1
BEX4 brain expressed, X-linked 4
C5AR2 complement component 5a receptor 2
CCDC68 coiled-coil domain containing 68
CCNK cyclin K
CCP110 centriolar coiled coil protein 110kDa
CDK6 cyclin-dependent kinase 6
CLGN calmegin
CLSPN claspin
CNTFR ciliary neurotrophic factor receptor
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DGKE diacylglycerol kinase, epsilon 64kDa
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP2 dual specificity phosphatase 2
DUSP9 dual specificity phosphatase 9
DYSF dysferlin
EFNA3 ephrin-A3
FAM131A family with sequence similarity 131, member A
FAM155A family with sequence similarity 155, member A
FAM46C family with sequence similarity 46, member C
FBXL7 F-box and leucine-rich repeat protein 7
FBXO22 F-box protein 22
FBXO31 F-box protein 31
FGD1 FYVE, RhoGEF and PH domain containing 1
FOXN2 forkhead box N2
GK3P glycerol kinase 3 pseudogene
GLCE glucuronic acid epimerase
GNG3 guanine nucleotide binding protein (G protein), gamma 3
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HOXC13 homeobox C13
HOXC8 homeobox C8
HSPA1L heat shock 70kDa protein 1-like
HSPA2 heat shock 70kDa protein 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
INPP1 inositol polyphosphate-1-phosphatase
IPO8 importin 8
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KLHL25 kelch-like family member 25
LOC730101 uncharacterized LOC730101
LYRM9 LYR motif containing 9
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAST3 microtubule associated serine/threonine kinase 3
MFAP2 microfibrillar-associated protein 2
MMP2 matrix metallopeptidase 2
NME5 NME/NM23 family member 5
OCA2 oculocutaneous albinism II
PADI1 peptidyl arginine deiminase, type I
PAQR3 progestin and adipoQ receptor family member III
PCDHA6 protocadherin alpha 6
PDZRN3 PDZ domain containing ring finger 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G10 phospholipase A2, group X
PLAC4 placenta-specific 4
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRPH peripherin
PVRL3 poliovirus receptor-related 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB40AL RAB40A, member RAS oncogene family-like
RAB40C RAB40C, member RAS oncogene family
RFXAP regulatory factor X-associated protein
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIBC2 RIB43A domain with coiled-coils 2
RPL10L ribosomal protein L10-like
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT2 sirtuin 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SYCP2 synaptonemal complex protein 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEX40 testis expressed 40
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM209 transmembrane protein 209
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPST2 tyrosylprotein sulfotransferase 2
TRIM36 tripartite motif containing 36
TWF2 twinfilin actin binding protein 2
WDR33 WD repeat domain 33
ZBTB39 zinc finger and BTB domain containing 39
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF16 zinc finger protein 16
ZNF37BP zinc finger protein 37B, pseudogene