acebutolol-1493 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the acebutolol-1493 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACPP acid phosphatase, prostate
AIRE autoimmune regulator
AMH anti-Mullerian hormone
ANAPC13 anaphase promoting complex subunit 13
ANGPTL2 angiopoietin-like 2
ANKRD40 ankyrin repeat domain 40
APC adenomatous polyposis coli
ARHGAP44 Rho GTPase activating protein 44
ARTN artemin
BIN1 bridging integrator 1
BTBD2 BTB (POZ) domain containing 2
C11ORF68 chromosome 11 open reading frame 68
CA5BP1 carbonic anhydrase VB pseudogene 1
CABIN1 calcineurin binding protein 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACYBP calcyclin binding protein
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD8A CD8a molecule
CDK20 cyclin-dependent kinase 20
CES3 carboxylesterase 3
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CRTC1 CREB regulated transcription coactivator 1
CUL7 cullin 7
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DIEXF digestive organ expansion factor homolog (zebrafish)
DLC1 DLC1 Rho GTPase activating protein
DNAL4 dynein, axonemal, light chain 4
DOHH deoxyhypusine hydroxylase/monooxygenase
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EPHX2 epoxide hydrolase 2, cytoplasmic
EZR ezrin
FBLN1 fibulin 1
FDPS farnesyl diphosphate synthase
FGFR1 fibroblast growth factor receptor 1
FOXJ2 forkhead box J2
GK glycerol kinase
GOLGA2 golgin A2
GSTTP1 glutathione S-transferase theta pseudogene 1
HIST1H2BO histone cluster 1, H2bo
IDS iduronate 2-sulfatase
INSR insulin receptor
ISG20 interferon stimulated exonuclease gene 20kDa
ITGB5 integrin, beta 5
KAT6A K(lysine) acetyltransferase 6A
KAZN kazrin, periplakin interacting protein
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
LEPROT leptin receptor overlapping transcript
LMAN1 lectin, mannose-binding, 1
LRRC75B leucine rich repeat containing 75B
MBD1 methyl-CpG binding domain protein 1
METTL2B methyltransferase like 2B
MKL1 megakaryoblastic leukemia (translocation) 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NRF1 nuclear respiratory factor 1
OGFR opioid growth factor receptor
PCDHB12 protocadherin beta 12
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
POFUT1 protein O-fucosyltransferase 1
PORCN porcupine homolog (Drosophila)
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRAMEF11 PRAME family member 11
PSAT1 phosphoserine aminotransferase 1
PSG9 pregnancy specific beta-1-glycoprotein 9
PTPRS protein tyrosine phosphatase, receptor type, S
RAB11B RAB11B, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RETN resistin
RNF122 ring finger protein 122
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAPER S-phase cyclin A-associated protein in the ER
SCD5 stearoyl-CoA desaturase 5
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SETD1A SET domain containing 1A
SMAD3 SMAD family member 3
SORT1 sortilin 1
SPAG6 sperm associated antigen 6
SRPX sushi-repeat containing protein, X-linked
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TH tyrosine hydroxylase
TIMELESS timeless circadian clock
TMOD1 tropomodulin 1
TMPRSS4 transmembrane protease, serine 4
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TPM3 tropomyosin 3
TRAPPC9 trafficking protein particle complex 9
TSPAN9 tetraspanin 9
TTC28 tetratricopeptide repeat domain 28
WIPF1 WAS/WASL interacting protein family, member 1
ZNF639 zinc finger protein 639
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRE5 adhesion G protein-coupled receptor E5
ADM adrenomedullin
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMC6 armadillo repeat containing 6
ATAD5 ATPase family, AAA domain containing 5
ATP7B ATPase, Cu++ transporting, beta polypeptide
BATF basic leucine zipper transcription factor, ATF-like
C17ORF70 chromosome 17 open reading frame 70
C1ORF105 chromosome 1 open reading frame 105
C7ORF43 chromosome 7 open reading frame 43
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK3 cyclin-dependent kinase 3
CHST10 carbohydrate sulfotransferase 10
CNPY3 canopy FGF signaling regulator 3
CRABP1 cellular retinoic acid binding protein 1
CST6 cystatin E/M
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DOC2A double C2-like domains, alpha
DUSP2 dual specificity phosphatase 2
EGLN3 egl-9 family hypoxia-inducible factor 3
ELOVL4 ELOVL fatty acid elongase 4
EPHA2 EPH receptor A2
ERN1 endoplasmic reticulum to nucleus signaling 1
FBXL2 F-box and leucine-rich repeat protein 2
FOXN2 forkhead box N2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH2L G patch domain containing 2-like
GRTP1 growth hormone regulated TBC protein 1
H2AFJ H2A histone family, member J
HSPA1L heat shock 70kDa protein 1-like
IL15RA interleukin 15 receptor, alpha
IRF2 interferon regulatory factor 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLC2 kinesin light chain 2
KLHL25 kelch-like family member 25
LHX6 LIM homeobox 6
LMBR1L limb development membrane protein 1-like
LOC390998 ribosomal protein L10 pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBP2 latent transforming growth factor beta binding protein 2
MANBA mannosidase, beta A, lysosomal
MAP1S microtubule-associated protein 1S
MAPK12 mitogen-activated protein kinase 12
MON1B MON1 secretory trafficking family member B
MVD mevalonate (diphospho) decarboxylase
NDRG4 NDRG family member 4
NECAP2 NECAP endocytosis associated 2
OLFML2A olfactomedin-like 2A
OSMR oncostatin M receptor
P3H1 prolyl 3-hydroxylase 1
PLA2G10 phospholipase A2, group X
PLD2 phospholipase D2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXNA3 plexin A3
PRKCE protein kinase C, epsilon
PRR4 proline rich 4 (lacrimal)
RABL3 RAB, member of RAS oncogene family-like 3
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RGS19 regulator of G-protein signaling 19
RIN2 Ras and Rab interactor 2
RNF121 ring finger protein 121
RNF126P1 ring finger protein 126 pseudogene 1
RNF43 ring finger protein 43
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC22A14 solute carrier family 22, member 14
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLMO1 slowmo homolog 1 (Drosophila)
SNAI2 snail family zinc finger 2
SND1-IT1 SND1 intronic transcript 1
SRD5A3 steroid 5 alpha-reductase 3
SSBP3 single stranded DNA binding protein 3
SYNGR3 synaptogyrin 3
TDRD1 tudor domain containing 1
TGFBI transforming growth factor, beta-induced, 68kDa
TLN1 talin 1
TTC33 tetratricopeptide repeat domain 33
USP36 ubiquitin specific peptidase 36
VGF VGF nerve growth factor inducible
VIPR1 vasoactive intestinal peptide receptor 1
VPS9D1 VPS9 domain containing 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF205 zinc finger protein 205
ZNF211 zinc finger protein 211
ZNF254 zinc finger protein 254
ZNF675 zinc finger protein 675
ZSCAN31 zinc finger and SCAN domain containing 31