| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the acebutolol-1911 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACAN | aggrecan |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANAPC2 | anaphase promoting complex subunit 2 |
| APOM | apolipoprotein M |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CAPN5 | calpain 5 |
| CCDC85B | coiled-coil domain containing 85B |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD47 | CD47 molecule |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLDN15 | claudin 15 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNPY3 | canopy FGF signaling regulator 3 |
| COASY | CoA synthase |
| COL4A1 | collagen, type IV, alpha 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| COPE | coatomer protein complex, subunit epsilon |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNASE2 | deoxyribonuclease II, lysosomal |
| FAM188A | family with sequence similarity 188, member A |
| FASTK | Fas-activated serine/threonine kinase |
| FLCN | folliculin |
| FOSL2 | FOS-like antigen 2 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GPR3 | G protein-coupled receptor 3 |
| GRK6 | G protein-coupled receptor kinase 6 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IL11 | interleukin 11 |
| IL13RA1 | interleukin 13 receptor, alpha 1 |
| KPTN | kaptin (actin binding protein) |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LIMK2 | LIM domain kinase 2 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LMF2 | lipase maturation factor 2 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MCOLN1 | mucolipin 1 |
| MED25 | mediator complex subunit 25 |
| METTL7A | methyltransferase like 7A |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MXD4 | MAX dimerization protein 4 |
| MYO9A | myosin IXA |
| MYT1 | myelin transcription factor 1 |
| NAAA | N-acylethanolamine acid amidase |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOTCH2 | notch 2 |
| NPAT | nuclear protein, ataxia-telangiectasia locus |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 |
| OR2S2 | olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PLXNB2 | plexin B2 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRRC2B | proline-rich coiled-coil 2B |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RARG | retinoic acid receptor, gamma |
| RECQL5 | RecQ protein-like 5 |
| RGS10 | regulator of G-protein signaling 10 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| SAMHD1 | SAM domain and HD domain 1 |
| SEC23A | Sec23 homolog A (S. cerevisiae) |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 |
| SLK | STE20-like kinase |
| SNX2 | sorting nexin 2 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TCF4 | transcription factor 4 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEX40 | testis expressed 40 |
| TK2 | thymidine kinase 2, mitochondrial |
| TLN2 | talin 2 |
| TRD | T cell receptor delta locus |
| TTC38 | tetratricopeptide repeat domain 38 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UBTF | upstream binding transcription factor, RNA polymerase I |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WIZ | widely interspaced zinc finger motifs |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF124 | zinc finger protein 124 |
| Symbol | Name |
|---|---|
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 |
| AIM1 | absent in melanoma 1 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 |
| ATXN2 | ataxin 2 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CBR4 | carbonyl reductase 4 |
| CCNA1 | cyclin A1 |
| CD302 | CD302 molecule |
| CLK2 | CDC-like kinase 2 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CPOX | coproporphyrinogen oxidase |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| DMXL1 | Dmx-like 1 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ERCC5 | excision repair cross-complementation group 5 |
| FAM102A | family with sequence similarity 102, member A |
| FAM172A | family with sequence similarity 172, member A |
| FDXR | ferredoxin reductase |
| FMO4 | flavin containing monooxygenase 4 |
| GDI1 | GDP dissociation inhibitor 1 |
| GOLGA8B | golgin A8 family, member B |
| GPATCH3 | G patch domain containing 3 |
| GTPBP8 | GTP-binding protein 8 (putative) |
| H2AFY2 | H2A histone family, member Y2 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HINFP | histone H4 transcription factor |
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 |
| KCTD9 | potassium channel tetramerization domain containing 9 |
| KIAA1551 | KIAA1551 |
| KLHL2 | kelch-like family member 2 |
| KRT75 | keratin 75, type II |
| KRT86 | keratin 86, type II |
| MAD2L1BP | MAD2L1 binding protein |
| MAVS | mitochondrial antiviral signaling protein |
| MED23 | mediator complex subunit 23 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MT1HL1 | metallothionein 1H-like 1 |
| MXRA7 | matrix-remodelling associated 7 |
| MYNN | myoneurin |
| NMD3 | NMD3 ribosome export adaptor |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 |
| OXR1 | oxidation resistance 1 |
| PDCD10 | programmed cell death 10 |
| PEX13 | peroxisomal biogenesis factor 13 |
| PIGK | phosphatidylinositol glycan anchor biosynthesis, class K |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| POU2F1 | POU class 2 homeobox 1 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PPT1 | palmitoyl-protein thioesterase 1 |
| PRSS23 | protease, serine, 23 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB20 | RAB20, member RAS oncogene family |
| RAD54L | RAD54-like (S. cerevisiae) |
| RCOR3 | REST corepressor 3 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RNF122 | ring finger protein 122 |
| RNF220 | ring finger protein 220 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SALL2 | spalt-like transcription factor 2 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SH2B3 | SH2B adaptor protein 3 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SOAT1 | sterol O-acyltransferase 1 |
| TBC1D12 | TBC1 domain family, member 12 |
| TBX3 | T-box 3 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TK1 | thymidine kinase 1, soluble |
| TMEM183A | transmembrane protein 183A |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TSLIG2 | tRNA splicing ligase complex subunit 2 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTC26 | tetratricopeptide repeat domain 26 |
| TULP4 | tubby like protein 4 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WASF3 | WAS protein family, member 3 |
| WDR13 | WD repeat domain 13 |
| ZNF562 | zinc finger protein 562 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |