| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the acebutolol-1993 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ADAM30 | ADAM metallopeptidase domain 30 |
| ASXL1 | additional sex combs like transcriptional regulator 1 |
| ATP11A | ATPase, class VI, type 11A |
| CCDC101 | coiled-coil domain containing 101 |
| CCHCR1 | coiled-coil alpha-helical rod protein 1 |
| CD1A | CD1a molecule |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CER1 | cerberus 1, DAN family BMP antagonist |
| CES3 | carboxylesterase 3 |
| CFAP74 | cilia and flagella associated protein 74 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CKB | creatine kinase, brain |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DMXL2 | Dmx-like 2 |
| DNASE1L1 | deoxyribonuclease I-like 1 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DUSP2 | dual specificity phosphatase 2 |
| ERLIN2 | ER lipid raft associated 2 |
| FAM106A | family with sequence similarity 106, member A |
| FAM192A | family with sequence similarity 192, member A |
| FBXO31 | F-box protein 31 |
| FKBP1A | FK506 binding protein 1A, 12kDa |
| FLOT1 | flotillin 1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GAA | glucosidase, alpha; acid |
| GDF9 | growth differentiation factor 9 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPR12 | G protein-coupled receptor 12 |
| HDC | histidine decarboxylase |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| HNF1B | HNF1 homeobox B |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| ING4 | inhibitor of growth family, member 4 |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| ITGA7 | integrin, alpha 7 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDM6A | lysine (K)-specific demethylase 6A |
| KYNU | kynureninase |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LPIN2 | lipin 2 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| LY75 | lymphocyte antigen 75 |
| MISP | mitotic spindle positioning |
| MLYCD | malonyl-CoA decarboxylase |
| MZF1 | myeloid zinc finger 1 |
| NBAS | neuroblastoma amplified sequence |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NKX3-1 | NK3 homeobox 1 |
| OGG1 | 8-oxoguanine DNA glycosylase |
| OSBPL7 | oxysterol binding protein-like 7 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCDHB6 | protocadherin beta 6 |
| PCGF2 | polycomb group ring finger 2 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| POR | P450 (cytochrome) oxidoreductase |
| PPCDC | phosphopantothenoylcysteine decarboxylase |
| PPP2R4 | protein phosphatase 2A activator, regulatory subunit 4 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RABIF | RAB interacting factor |
| RGS1 | regulator of G-protein signaling 1 |
| RRBP1 | ribosome binding protein 1 |
| RWDD3 | RWD domain containing 3 |
| SGSM3 | small G protein signaling modulator 3 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SNX11 | sorting nexin 11 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) |
| STK19 | serine/threonine kinase 19 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TFCP2L1 | transcription factor CP2-like 1 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNS1 | tensin 1 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRD | T cell receptor delta locus |
| TTC23 | tetratricopeptide repeat domain 23 |
| UNC45A | unc-45 homolog A (C. elegans) |
| XAB2 | XPA binding protein 2 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF408 | zinc finger protein 408 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADRB2 | adrenoceptor beta 2, surface |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ASRGL1 | asparaginase like 1 |
| ATG4A | autophagy related 4A, cysteine peptidase |
| BCL7B | B-cell CLL/lymphoma 7B |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C3 | complement component 3 |
| CCDC91 | coiled-coil domain containing 91 |
| CEP85 | centrosomal protein 85kDa |
| COMMD10 | COMM domain containing 10 |
| CORO7 | coronin 7 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DCTN4 | dynactin 4 (p62) |
| DDA1 | DET1 and DDB1 associated 1 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FOXM1 | forkhead box M1 |
| GBAS | glioblastoma amplified sequence |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GOLGA7 | golgin A7 |
| GPATCH2 | G patch domain containing 2 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| GTPBP2 | GTP binding protein 2 |
| HAGH | hydroxyacylglutathione hydrolase |
| HCCS | holocytochrome c synthase |
| HDHD1 | haloacid dehalogenase-like hydrolase domain containing 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 |
| IFNA17 | interferon, alpha 17 |
| INO80D | INO80 complex subunit D |
| INSIG2 | insulin induced gene 2 |
| INTS9 | integrator complex subunit 9 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0430 | KIAA0430 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LACTB2 | lactamase, beta 2 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| MED4 | mediator complex subunit 4 |
| MITF | microphthalmia-associated transcription factor |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MXRA8 | matrix-remodelling associated 8 |
| MYL12B | myosin, light chain 12B, regulatory |
| NMRK1 | nicotinamide riboside kinase 1 |
| ORC2 | origin recognition complex, subunit 2 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RECQL4 | RecQ protein-like 4 |
| RNF144A | ring finger protein 144A |
| RNF220 | ring finger protein 220 |
| RPL39L | ribosomal protein L39-like |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC25A46 | solute carrier family 25, member 46 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMNDC1 | survival motor neuron domain containing 1 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBPL1 | TBP-like 1 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 |
| TMEM123 | transmembrane protein 123 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM184B | transmembrane protein 184B |
| TOM1L1 | target of myb1 (chicken)-like 1 |
| TRIM52 | tripartite motif containing 52 |
| TTC1 | tetratricopeptide repeat domain 1 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USP11 | ubiquitin specific peptidase 11 |
| USP39 | ubiquitin specific peptidase 39 |
| USP8 | ubiquitin specific peptidase 8 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZNF140 | zinc finger protein 140 |
| ZNF85 | zinc finger protein 85 |
