acemetacin-5460 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the acemetacin-5460 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACTN2 actinin, alpha 2
AKR1C1 aldo-keto reductase family 1, member C1
ALS2CL ALS2 C-terminal like
APOL2 apolipoprotein L, 2
ARC activity-regulated cytoskeleton-associated protein
ARHGAP26 Rho GTPase activating protein 26
ASPN asporin
ATN1 atrophin 1
ATP10B ATPase, class V, type 10B
C11ORF63 chromosome 11 open reading frame 63
C1QL1 complement component 1, q subcomponent-like 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD1A CD1a molecule
CDRT1 CMT1A duplicated region transcript 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COL5A1 collagen, type V, alpha 1
CTIF CBP80/20-dependent translation initiation factor
CYLD cylindromatosis (turban tumor syndrome)
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DBP D site of albumin promoter (albumin D-box) binding protein
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DICER1 dicer 1, ribonuclease type III
DOPEY2 dopey family member 2
ERCC2 excision repair cross-complementation group 2
FABP3 fatty acid binding protein 3, muscle and heart
FASLG Fas ligand (TNF superfamily, member 6)
FUT2 fucosyltransferase 2 (secretor status included)
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
GFER growth factor, augmenter of liver regeneration
GLS glutaminase
GM2A GM2 ganglioside activator
GRAP GRB2-related adaptor protein
HDAC7 histone deacetylase 7
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HOXB2 homeobox B2
HSF2BP heat shock transcription factor 2 binding protein
ING4 inhibitor of growth family, member 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KDM8 lysine (K)-specific demethylase 8
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MAP4 microtubule-associated protein 4
MAPK10 mitogen-activated protein kinase 10
MEF2D myocyte enhancer factor 2D
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MINK1 misshapen-like kinase 1
MKRN3 makorin ring finger protein 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAG18 NAG18 mRNA
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEU3 sialidase 3 (membrane sialidase)
NEUROD1 neuronal differentiation 1
NUPR1 nuclear protein, transcriptional regulator, 1
OASL 2'-5'-oligoadenylate synthetase-like
PAX5 paired box 5
PDAP1 PDGFA associated protein 1
PHOX2A paired-like homeobox 2a
PIDD1 p53-induced death domain protein 1
PKP2 plakophilin 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLM polymerase (DNA directed), mu
PPP4R4 protein phosphatase 4, regulatory subunit 4
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RELN reelin
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC35E2 solute carrier family 35, member E2
SMAD3 SMAD family member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SP100 SP100 nuclear antigen
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRP72 signal recognition particle 72kDa
SSTR5 somatostatin receptor 5
STK17B serine/threonine kinase 17b
SULT4A1 sulfotransferase family 4A, member 1
TAGLN3 transgelin 3
TAS2R1 taste receptor, type 2, member 1
TAS2R16 taste receptor, type 2, member 16
TBX2 T-box 2
TBX5 T-box 5
TICAM1 toll-like receptor adaptor molecule 1
TP63 tumor protein p63
TRAPPC9 trafficking protein particle complex 9
TRBC1 T cell receptor beta constant 1
TRD T cell receptor delta locus
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USP20 ubiquitin specific peptidase 20
VCX2 variable charge, X-linked 2
VGLL1 vestigial-like family member 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF280A zinc finger protein 280A
ZNF423 zinc finger protein 423
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACBD4 acyl-CoA binding domain containing 4
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCY6 adenylate cyclase 6
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATP10D ATPase, class V, type 10D
BAHD1 bromo adjacent homology domain containing 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTBD2 BTB (POZ) domain containing 2
CCNO cyclin O
CD82 CD82 molecule
CEMIP cell migration inducing protein, hyaluronan binding
CENPC centromere protein C
CGA glycoprotein hormones, alpha polypeptide
CLGN calmegin
CST6 cystatin E/M
CTAGE9 CTAGE family, member 9
DBF4B DBF4 zinc finger B
DGKE diacylglycerol kinase, epsilon 64kDa
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK4 dedicator of cytokinesis 4
ELMO3 engulfment and cell motility 3
FAM212B family with sequence similarity 212, member B
FBXO31 F-box protein 31
FLJ22184
GBP2 guanylate binding protein 2, interferon-inducible
GMPR guanosine monophosphate reductase
GPR143 G protein-coupled receptor 143
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H4A histone cluster 1, H4a
HLA-DMA major histocompatibility complex, class II, DM alpha
HMOX1 heme oxygenase 1
IFT81 intraflagellar transport 81
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL15RA interleukin 15 receptor, alpha
IL17RA interleukin 17 receptor A
INF2 inverted formin, FH2 and WH2 domain containing
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF2BP1 interferon regulatory factor 2 binding protein 1
KRT13 keratin 13, type I
LAMB3 laminin, beta 3
LIN7B lin-7 homolog B (C. elegans)
MAPKBP1 mitogen-activated protein kinase binding protein 1
MMP9 matrix metallopeptidase 9
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTHFSD methenyltetrahydrofolate synthetase domain containing
NME5 NME/NM23 family member 5
NOL10 nucleolar protein 10
NPIPB15 nuclear pore complex interacting protein family, member B15
NPIPB3 nuclear pore complex interacting protein family, member B3
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSGIN1 oxidative stress induced growth inhibitor 1
PCDHA6 protocadherin alpha 6
PHC1 polyhomeotic homolog 1 (Drosophila)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PODNL1 podocan-like 1
PODXL2 podocalyxin-like 2
POMT2 protein-O-mannosyltransferase 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PTDSS2 phosphatidylserine synthase 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
QSER1 glutamine and serine rich 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RASAL1 RAS protein activator like 1 (GAP1 like)
RFXAP regulatory factor X-associated protein
RUSC2 RUN and SH3 domain containing 2
SCML1 sex comb on midleg-like 1 (Drosophila)
SENP7 SUMO1/sentrin specific peptidase 7
SIX1 SIX homeobox 1
SLC12A8 solute carrier family 12, member 8
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SRD5A3 steroid 5 alpha-reductase 3
STEAP1 six transmembrane epithelial antigen of the prostate 1
STEAP4 STEAP family member 4
SYCP2 synaptonemal complex protein 2
TNK1 tyrosine kinase, non-receptor, 1
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
ULBP2 UL16 binding protein 2
UNC119 unc-119 homolog (C. elegans)
USP27X ubiquitin specific peptidase 27, X-linked
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF273 zinc finger protein 273
ZNF606 zinc finger protein 606
ZNF767P zinc finger family member 767, pseudogene
ZNF816 zinc finger protein 816