acenocoumarol-1394 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the acenocoumarol-1394 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ANKRD12 ankyrin repeat domain 12
ANKRD40 ankyrin repeat domain 40
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AQP8 aquaporin 8
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATR ATR serine/threonine kinase
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
C14ORF1 chromosome 14 open reading frame 1
CAND1 cullin-associated and neddylation-dissociated 1
CASD1 CAS1 domain containing 1
CCNG2 cyclin G2
CHEK1 checkpoint kinase 1
CIITA class II, major histocompatibility complex, transactivator
CRYM crystallin, mu
CUL5 cullin 5
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DBN1 drebrin 1
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DERL1 derlin 1
DERL2 derlin 2
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DSCR3 Down syndrome critical region 3
DUS2 dihydrouridine synthase 2
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EMC1 ER membrane protein complex subunit 1
FAM208A family with sequence similarity 208, member A
FAM63A family with sequence similarity 63, member A
FASTK Fas-activated serine/threonine kinase
FBXW11 F-box and WD repeat domain containing 11
FCHO1 FCH domain only 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GPX2 glutathione peroxidase 2
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
ICAM1 intercellular adhesion molecule 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
KCTD2 potassium channel tetramerization domain containing 2
KRAS Kirsten rat sarcoma viral oncogene homolog
KRI1 KRI1 homolog (S. cerevisiae)
LTN1 listerin E3 ubiquitin protein ligase 1
MBD4 methyl-CpG binding domain protein 4
MBD5 methyl-CpG binding domain protein 5
MBTD1 mbt domain containing 1
MED13L mediator complex subunit 13-like
MED6 mediator complex subunit 6
MFN1 mitofusin 1
MID2 midline 2
NBEAL2 neurobeachin-like 2
NFX1 nuclear transcription factor, X-box binding 1
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NR2F6 nuclear receptor subfamily 2, group F, member 6
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
NVL nuclear VCP-like
OCRL oculocerebrorenal syndrome of Lowe
ODF2 outer dense fiber of sperm tails 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCIF1 PDX1 C-terminal inhibiting factor 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PGRMC1 progesterone receptor membrane component 1
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PRDM11 PR domain containing 11
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RANBP10 RAN binding protein 10
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBM34 RNA binding motif protein 34
RPS14P3 ribosomal protein S14 pseudogene 3
SAP30 Sin3A-associated protein, 30kDa
SCAMP1 secretory carrier membrane protein 1
SEC14L4 SEC14-like 4 (S. cerevisiae)
SECISBP2L SECIS binding protein 2-like
SMAD5 SMAD family member 5
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMC2 structural maintenance of chromosomes 2
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNRPF small nuclear ribonucleoprotein polypeptide F
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRP72 signal recognition particle 72kDa
STXBP1 syntaxin binding protein 1
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
THBS3 thrombospondin 3
TLE3 transducin-like enhancer of split 3
TRADD TNFRSF1A-associated via death domain
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPAN3 tetraspanin 3
TTC3 tetratricopeptide repeat domain 3
TULP4 tubby like protein 4
USP46 ubiquitin specific peptidase 46
VWA9 von Willebrand factor A domain containing 9
WDR13 WD repeat domain 13
WDR46 WD repeat domain 46
WDR48 WD repeat domain 48
WIPF2 WAS/WASL interacting protein family, member 2
YIPF6 Yip1 domain family, member 6
ZDHHC6 zinc finger, DHHC-type containing 6
ZNF337 zinc finger protein 337
ZNHIT2 zinc finger, HIT-type containing 2
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACYP2 acylphosphatase 2, muscle type
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOC4 apolipoprotein C-IV
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ASAP1-IT1 ASAP1 intronic transcript 1
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
BCKDK branched chain ketoacid dehydrogenase kinase
C6ORF47 chromosome 6 open reading frame 47
CA7 carbonic anhydrase VII
CCDC109B coiled-coil domain containing 109B
CCDC176 coiled-coil domain containing 176
CCDC25 coiled-coil domain containing 25
CD151 CD151 molecule (Raph blood group)
CDK5 cyclin-dependent kinase 5
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CIDEB cell death-inducing DFFA-like effector b
COPS7B COP9 signalosome subunit 7B
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
DCAF10 DDB1 and CUL4 associated factor 10
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DOK2 docking protein 2, 56kDa
DPF3 D4, zinc and double PHD fingers, family 3
EDAR ectodysplasin A receptor
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
ELSPBP1 epididymal sperm binding protein 1
FAM114A2 family with sequence similarity 114, member A2
FAM53B family with sequence similarity 53, member B
FBXL6 F-box and leucine-rich repeat protein 6
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GDAP2 ganglioside induced differentiation associated protein 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GTPBP6 GTP binding protein 6 (putative)
IL2RB interleukin 2 receptor, beta
INF2 inverted formin, FH2 and WH2 domain containing
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD15 potassium channel tetramerization domain containing 15
KCTD3 potassium channel tetramerization domain containing 3
KLF13 Kruppel-like factor 13
LACTB2 lactamase, beta 2
LINC00339 long intergenic non-protein coding RNA 339
LOC642236 FSHD region gene 1 pseudogene
LPAR6 lysophosphatidic acid receptor 6
LTB lymphotoxin beta (TNF superfamily, member 3)
MAP7D3 MAP7 domain containing 3
MAPK3 mitogen-activated protein kinase 3
MBIP MAP3K12 binding inhibitory protein 1
MED17 mediator complex subunit 17
MED9 mediator complex subunit 9
MMP2 matrix metallopeptidase 2
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NECAB3 N-terminal EF-hand calcium binding protein 3
NIP7 NIP7, nucleolar pre-rRNA processing protein
NRBP1 nuclear receptor binding protein 1
NXPH3 neurexophilin 3
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PADI1 peptidyl arginine deiminase, type I
PHF21A PHD finger protein 21A
PIGR polymeric immunoglobulin receptor
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMM1 phosphomannomutase 1
PSKH1 protein serine kinase H1
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RIN1 Ras and Rab interactor 1
RPS27A ribosomal protein S27a
SFMBT1 Scm-like with four mbt domains 1
SH2B2 SH2B adaptor protein 2
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SRRD SRR1 domain containing
STK39 serine threonine kinase 39
SUSD6 sushi domain containing 6
TAC3 tachykinin 3
TERT telomerase reverse transcriptase
TEX40 testis expressed 40
TLR2 toll-like receptor 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMBIM4 transmembrane BAX inhibitor motif containing 4
TTC4 tetratricopeptide repeat domain 4
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast)
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WASF2 WAS protein family, member 2
WDR19 WD repeat domain 19
WDR7 WD repeat domain 7
XBP1 X-box binding protein 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF274 zinc finger protein 274
ZNF562 zinc finger protein 562
ZNF8 zinc finger protein 8
ZXDC ZXD family zinc finger C