acenocoumarol-2077 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the acenocoumarol-2077 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRB2 adhesion G protein-coupled receptor B2
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AKAP13 A kinase (PRKA) anchor protein 13
AKIP1 A kinase (PRKA) interacting protein 1
ALPP alkaline phosphatase, placental
ANKMY1 ankyrin repeat and MYND domain containing 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ATAT1 alpha tubulin acetyltransferase 1
BBC3 BCL2 binding component 3
C9ORF9 chromosome 9 open reading frame 9
CABIN1 calcineurin binding protein 1
CACFD1 calcium channel flower domain containing 1
CAPN10 calpain 10
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASZ1 castor zinc finger 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDON cell adhesion associated, oncogene regulated
CLCN7 chloride channel, voltage-sensitive 7
COL5A1 collagen, type V, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CST1 cystatin SN
CYB5R2 cytochrome b5 reductase 2
DCAF15 DDB1 and CUL4 associated factor 15
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DPP4 dipeptidyl-peptidase 4
ERN2 endoplasmic reticulum to nucleus signaling 2
EWSR1 EWS RNA-binding protein 1
FCMR Fc fragment of IgM receptor
FGFR4 fibroblast growth factor receptor 4
FLJ22184
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAMT guanidinoacetate N-methyltransferase
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GM2A GM2 ganglioside activator
GPR37L1 G protein-coupled receptor 37 like 1
GREM1 gremlin 1, DAN family BMP antagonist
GSDMD gasdermin D
HEG1 heart development protein with EGF-like domains 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXA10 homeobox A10
ICA1 islet cell autoantigen 1, 69kDa
INO80B INO80 complex subunit B
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIDINS220 kinase D-interacting substrate, 220kDa
KLK7 kallikrein-related peptidase 7
KRT17 keratin 17, type I
LAT2 linker for activation of T cells family, member 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LINC00094 long intergenic non-protein coding RNA 94
LMCD1 LIM and cysteine-rich domains 1
LPIN2 lipin 2
MAMLD1 mastermind-like domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCF2L MCF.2 cell line derived transforming sequence-like
MIIP migration and invasion inhibitory protein
MOCS1 molybdenum cofactor synthesis 1
NNMT nicotinamide N-methyltransferase
NOTCH1 notch 1
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OVGP1 oviductal glycoprotein 1, 120kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PHF7 PHD finger protein 7
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PLEC plectin
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POM121 POM121 transmembrane nucleoporin
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RARG retinoic acid receptor, gamma
RBMS3 RNA binding motif, single stranded interacting protein 3
RIBC2 RIB43A domain with coiled-coils 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPS9 ribosomal protein S9
S1PR1 sphingosine-1-phosphate receptor 1
SCNN1B sodium channel, non voltage gated 1 beta subunit
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SLC43A3 solute carrier family 43, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOD3 superoxide dismutase 3, extracellular
SUGP1 SURP and G patch domain containing 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TLR2 toll-like receptor 2
TM2D1 TM2 domain containing 1
TRAFD1 TRAF-type zinc finger domain containing 1
TTC38 tetratricopeptide repeat domain 38
UBQLN4 ubiquilin 4
WHSC1 Wolf-Hirschhorn syndrome candidate 1
ZC3H7B zinc finger CCCH-type containing 7B
ZFPL1 zinc finger protein-like 1
ZNF358 zinc finger protein 358
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
ACVR2A activin A receptor, type IIA
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARHGAP5 Rho GTPase activating protein 5
ARRB2 arrestin, beta 2
ARSJ arylsulfatase family, member J
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAHD1 bromo adjacent homology domain containing 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CFAP44 cilia and flagella associated protein 44
COBL cordon-bleu WH2 repeat protein
CPA4 carboxypeptidase A4
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
CSAD cysteine sulfinic acid decarboxylase
CTAGE9 CTAGE family, member 9
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCLRE1A DNA cross-link repair 1A
DCLRE1B DNA cross-link repair 1B
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNM1 dynamin 1
DPY19L2P2 DPY19L2 pseudogene 2
DTWD1 DTW domain containing 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
FBXL7 F-box and leucine-rich repeat protein 7
FBXO2 F-box protein 2
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GLCE glucuronic acid epimerase
GLT8D2 glycosyltransferase 8 domain containing 2
GMIP GEM interacting protein
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH2L G patch domain containing 2-like
GRWD1 glutamate-rich WD repeat containing 1
HIRA histone cell cycle regulator
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMG20A high mobility group 20A
INPPL1 inositol polyphosphate phosphatase-like 1
IRF1 interferon regulatory factor 1
JADE1 jade family PHD finger 1
KDM5C lysine (K)-specific demethylase 5C
KIAA0895 KIAA0895
KIAA1551 KIAA1551
KPNA4 karyopherin alpha 4 (importin alpha 3)
KPTN kaptin (actin binding protein)
LHFP lipoma HMGIC fusion partner
LMNB1 lamin B1
MFGE8 milk fat globule-EGF factor 8 protein
MIS18BP1 MIS18 binding protein 1
MTERF1 mitochondrial transcription termination factor 1
MYO1E myosin IE
NDE1 nudE neurodevelopment protein 1
NHLRC2 NHL repeat containing 2
NIP7 NIP7, nucleolar pre-rRNA processing protein
NOL12 nucleolar protein 12
NPY1R neuropeptide Y receptor Y1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
ORAI3 ORAI calcium release-activated calcium modulator 3
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PAQR6 progestin and adipoQ receptor family member VI
PEG3 paternally expressed 3
PPT2 palmitoyl-protein thioesterase 2
PYCR1 pyrroline-5-carboxylate reductase 1
RAD51AP1 RAD51 associated protein 1
RNF220 ring finger protein 220
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEPP1 selenoprotein P, plasma, 1
SETD6 SET domain containing 6
SIX1 SIX homeobox 1
SLC22A18 solute carrier family 22, member 18
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNHG20 small nucleolar RNA host gene 20
SP140L SP140 nuclear body protein-like
SPATA7 spermatogenesis associated 7
SPEG SPEG complex locus
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
SUGCT succinyl-CoA:glutarate-CoA transferase
SYNPO synaptopodin
SYT17 synaptotagmin XVII
TBCCD1 TBCC domain containing 1
TMC5 transmembrane channel-like 5
TMCC2 transmembrane and coiled-coil domain family 2
TMEM209 transmembrane protein 209
TNRC6B trinucleotide repeat containing 6B
TPRA1 transmembrane protein, adipocyte asscociated 1
TRDMT1 tRNA aspartic acid methyltransferase 1
TUBB2B tubulin, beta 2B class IIb
UNKL unkempt family zinc finger-like
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZC3H12A zinc finger CCCH-type containing 12A
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF124 zinc finger protein 124
ZNF571 zinc finger protein 571
ZNF8 zinc finger protein 8