| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the acepromazine-1777 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADCY6 | adenylate cyclase 6 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ATF6B | activating transcription factor 6 beta |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| ATXN2L | ataxin 2-like |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| C8B | complement component 8, beta polypeptide |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CCDC186 | coiled-coil domain containing 186 |
| CDHR2 | cadherin-related family member 2 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CSNK1D | casein kinase 1, delta |
| CYB5R3 | cytochrome b5 reductase 3 |
| DBF4B | DBF4 zinc finger B |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DLX2 | distal-less homeobox 2 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DOLPP1 | dolichyldiphosphatase 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| EGR1 | early growth response 1 |
| ERCC8 | excision repair cross-complementation group 8 |
| FAM134B | family with sequence similarity 134, member B |
| FBRS | fibrosin |
| GCDH | glutaryl-CoA dehydrogenase |
| GIMAP5 | GTPase, IMAP family member 5 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPSM3 | G-protein signaling modulator 3 |
| GSDMD | gasdermin D |
| GSTA4 | glutathione S-transferase alpha 4 |
| HIST1H3E | histone cluster 1, H3e |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| ICAM1 | intercellular adhesion molecule 1 |
| IL9R | interleukin 9 receptor |
| INHBC | inhibin, beta C |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MT3 | metallothionein 3 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MYO9B | myosin IXB |
| NEFH | neurofilament, heavy polypeptide |
| NKX3-1 | NK3 homeobox 1 |
| NUP205 | nucleoporin 205kDa |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PHB | prohibitin |
| PHOX2B | paired-like homeobox 2b |
| PIDD1 | p53-induced death domain protein 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| POLRMT | polymerase (RNA) mitochondrial (DNA directed) |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 |
| RABIF | RAB interacting factor |
| RASL11B | RAS-like, family 11, member B |
| RPS11 | ribosomal protein S11 |
| SAPCD1 | suppressor APC domain containing 1 |
| SENP5 | SUMO1/sentrin specific peptidase 5 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SFN | stratifin |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SPATA2L | spermatogenesis associated 2-like |
| SPN | sialophorin |
| SRCAP | Snf2-related CREBBP activator protein |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TGIF2 | TGFB-induced factor homeobox 2 |
| TMEM161A | transmembrane protein 161A |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TPD52L1 | tumor protein D52-like 1 |
| TRIM9 | tripartite motif containing 9 |
| TRMT61A | tRNA methyltransferase 61A |
| TULP3 | tubby like protein 3 |
| URI1 | URI1, prefoldin-like chaperone |
| USP46 | ubiquitin specific peptidase 46 |
| WDR44 | WD repeat domain 44 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZNF226 | zinc finger protein 226 |
| ZNF232 | zinc finger protein 232 |
| ZNF518A | zinc finger protein 518A |
| ZNF764 | zinc finger protein 764 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ADAM9 | ADAM metallopeptidase domain 9 |
| AIDA | axin interactor, dorsalization associated |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ANKRD10 | ankyrin repeat domain 10 |
| ATAD2 | ATPase family, AAA domain containing 2 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BCAP31 | B-cell receptor-associated protein 31 |
| BCL2A1 | BCL2-related protein A1 |
| BRMS1 | breast cancer metastasis suppressor 1 |
| C1ORF216 | chromosome 1 open reading frame 216 |
| C1ORF27 | chromosome 1 open reading frame 27 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD33 | CD33 molecule |
| CDC37 | cell division cycle 37 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLK3 | CDC-like kinase 3 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| COMMD10 | COMM domain containing 10 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CS | citrate synthase |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DPYSL2 | dihydropyrimidinase-like 2 |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 |
| E2F6 | E2F transcription factor 6 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ERH | enhancer of rudimentary homolog (Drosophila) |
| EXOC5 | exocyst complex component 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAF1 | Fas (TNFRSF6) associated factor 1 |
| FAM188A | family with sequence similarity 188, member A |
| FAM222B | family with sequence similarity 222, member B |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| GAB2 | GRB2-associated binding protein 2 |
| GPR183 | G protein-coupled receptor 183 |
| GTF2I | general transcription factor IIi |
| IL10RB | interleukin 10 receptor, beta |
| INSIG2 | insulin induced gene 2 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIF18A | kinesin family member 18A |
| LAP3 | leucine aminopeptidase 3 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MAP2K1 | mitogen-activated protein kinase kinase 1 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MGMT | O-6-methylguanine-DNA methyltransferase |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| NCOA4 | nuclear receptor coactivator 4 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| NECAP1 | NECAP endocytosis associated 1 |
| NLRX1 | NLR family member X1 |
| NMD3 | NMD3 ribosome export adaptor |
| NRBF2 | nuclear receptor binding factor 2 |
| NVL | nuclear VCP-like |
| ORC2 | origin recognition complex, subunit 2 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PRCC | papillary renal cell carcinoma (translocation-associated) |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RPIA | ribose 5-phosphate isomerase A |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A |
| RSBN1 | round spermatid basic protein 1 |
| SCPEP1 | serine carboxypeptidase 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SFT2D2 | SFT2 domain containing 2 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC35A5 | solute carrier family 35, member A5 |
| SPIN1 | spindlin 1 |
| SPON2 | spondin 2, extracellular matrix protein |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| THOC1 | THO complex 1 |
| TMEM38B | transmembrane protein 38B |
| TUBA1A | tubulin, alpha 1a |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| USP39 | ubiquitin specific peptidase 39 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| WDR76 | WD repeat domain 76 |
| WEE1 | WEE1 G2 checkpoint kinase |
| ZEB2 | zinc finger E-box binding homeobox 2 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 |
| ZNF175 | zinc finger protein 175 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| ZWILCH | zwilch kinetochore protein |