acepromazine-2769 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the acepromazine-2769 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAP2 ArfGAP with dual PH domains 2
ADD2 adducin 2 (beta)
ALDOB aldolase B, fructose-bisphosphate
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
C3 complement component 3
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CDK13 cyclin-dependent kinase 13
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CHAT choline O-acetyltransferase
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLSTN2 calsyntenin 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPA2 carboxypeptidase A2 (pancreatic)
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CSNK1G1 casein kinase 1, gamma 1
CTSF cathepsin F
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
ELOVL2 ELOVL fatty acid elongase 2
ESRRA estrogen-related receptor alpha
ETAA1 Ewing tumor-associated antigen 1
FBXL7 F-box and leucine-rich repeat protein 7
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FHL1 four and a half LIM domains 1
FLJ11292
FLJ22184
GFER growth factor, augmenter of liver regeneration
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GTPBP4 GTP binding protein 4
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H4E histone cluster 1, H4e
IDS iduronate 2-sulfatase
IFNA17 interferon, alpha 17
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL4R interleukin 4 receptor
IL5RA interleukin 5 receptor, alpha
INO80D INO80 complex subunit D
IQCA1 IQ motif containing with AAA domain 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KLHL22 kelch-like family member 22
LAMB3 laminin, beta 3
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LOX lysyl oxidase
MAP2K5 mitogen-activated protein kinase kinase 5
MAP4 microtubule-associated protein 4
MAPK14 mitogen-activated protein kinase 14
NCDN neurochondrin
NCR2 natural cytotoxicity triggering receptor 2
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NLRX1 NLR family member X1
OPCML opioid binding protein/cell adhesion molecule-like
OVGP1 oviductal glycoprotein 1, 120kDa
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCSK6 proprotein convertase subtilisin/kexin type 6
PDAP1 PDGFA associated protein 1
PDZK1IP1 PDZK1 interacting protein 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POPDC3 popeye domain containing 3
PPARD peroxisome proliferator-activated receptor delta
PTGDR2 prostaglandin D2 receptor 2
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RBMS2 RNA binding motif, single stranded interacting protein 2
RGS14 regulator of G-protein signaling 14
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RPL35A ribosomal protein L35a
RPS4Y1 ribosomal protein S4, Y-linked 1
SAFB scaffold attachment factor B
SARDH sarcosine dehydrogenase
SDC2 syndecan 2
SH2D3A SH2 domain containing 3A
SLC22A17 solute carrier family 22, member 17
SNTG1 syntrophin, gamma 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TBC1D2 TBC1 domain family, member 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TENM4 teneurin transmembrane protein 4
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1
TMEM53 transmembrane protein 53
TUBA3C tubulin, alpha 3c
TWF2 twinfilin actin binding protein 2
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VN1R1 vomeronasal 1 receptor 1
VPRBP Vpr (HIV-1) binding protein
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YIPF2 Yip1 domain family, member 2
ZDHHC14 zinc finger, DHHC-type containing 14
ZER1 zyg-11 related, cell cycle regulator
ZFP36L1 ZFP36 ring finger protein-like 1
ZFPL1 zinc finger protein-like 1

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACTL8 actin-like 8
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AGBL5 ATP/GTP binding protein-like 5
ALS2CL ALS2 C-terminal like
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AMPD1 adenosine monophosphate deaminase 1
ANKRD40 ankyrin repeat domain 40
ATG2A autophagy related 2A
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BRAF B-Raf proto-oncogene, serine/threonine kinase
C11ORF68 chromosome 11 open reading frame 68
C1ORF35 chromosome 1 open reading frame 35
C3ORF52 chromosome 3 open reading frame 52
C6ORF47 chromosome 6 open reading frame 47
C7ORF43 chromosome 7 open reading frame 43
CCDC9 coiled-coil domain containing 9
CCNO cyclin O
CFD complement factor D (adipsin)
CLCN6 chloride channel, voltage-sensitive 6
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CXORF56 chromosome X open reading frame 56
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAL4 dynein, axonemal, light chain 4
DNALI1 dynein, axonemal, light intermediate chain 1
ERN2 endoplasmic reticulum to nucleus signaling 2
F3 coagulation factor III (thromboplastin, tissue factor)
FANCC Fanconi anemia, complementation group C
FBXL2 F-box and leucine-rich repeat protein 2
FBXO31 F-box protein 31
FGD1 FYVE, RhoGEF and PH domain containing 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FOSL1 FOS-like antigen 1
GAMT guanidinoacetate N-methyltransferase
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPATCH3 G patch domain containing 3
GPR143 G protein-coupled receptor 143
GPX2 glutathione peroxidase 2
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC3 histone deacetylase 3
HIST1H2BO histone cluster 1, H2bo
HIST1H4D histone cluster 1, H4d
HMOX1 heme oxygenase 1
HOXC13 homeobox C13
KIAA1107 KIAA1107
KLHL12 kelch-like family member 12
KLHL36 kelch-like family member 36
LOC257152 uncharacterized LOC257152
LRRC8E leucine rich repeat containing 8 family, member E
LYRM9 LYR motif containing 9
MAST3 microtubule associated serine/threonine kinase 3
METTL16 methyltransferase like 16
MITF microphthalmia-associated transcription factor
MXD3 MAX dimerization protein 3
MYO1F myosin IF
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NPY1R neuropeptide Y receptor Y1
P3H1 prolyl 3-hydroxylase 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PELI1 pellino E3 ubiquitin protein ligase 1
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PRPH peripherin
QSER1 glutamine and serine rich 1
RAB4B RAB4B, member RAS oncogene family
RBM38 RNA binding motif protein 38
RNF126P1 ring finger protein 126 pseudogene 1
RPAP1 RNA polymerase II associated protein 1
SCD5 stearoyl-CoA desaturase 5
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFT2D2 SFT2 domain containing 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC12A9 solute carrier family 12, member 9
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLIT2 slit homolog 2 (Drosophila)
SMG9 SMG9 nonsense mediated mRNA decay factor
STRN striatin, calmodulin binding protein
TAOK1 TAO kinase 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM121 transmembrane protein 121
TMEM242 transmembrane protein 242
TMUB2 transmembrane and ubiquitin-like domain containing 2
TTF2 transcription termination factor, RNA polymerase II
TTLL1 tubulin tyrosine ligase-like family member 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VAX2 ventral anterior homeobox 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZBTB44 zinc finger and BTB domain containing 44
ZNF180 zinc finger protein 180
ZNF324 zinc finger protein 324
ZNF468 zinc finger protein 468
ZNF532 zinc finger protein 532
ZNF574 zinc finger protein 574
ZSCAN31 zinc finger and SCAN domain containing 31