acetazolamide-1808 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the acetazolamide-1808 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT7 acyl-CoA thioesterase 7
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASPH aspartate beta-hydroxylase
ATXN7L3B ataxin 7-like 3B
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BECN1 beclin 1, autophagy related
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
BRD4 bromodomain containing 4
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BTD biotinidase
C9ORF116 chromosome 9 open reading frame 116
CA12 carbonic anhydrase XII
CCNA1 cyclin A1
CCNT2 cyclin T2
CCPG1 cell cycle progression 1
CHML choroideremia-like (Rab escort protein 2)
CLCN4 chloride channel, voltage-sensitive 4
COL6A1 collagen, type VI, alpha 1
CPE carboxypeptidase E
CREM cAMP responsive element modulator
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAF8 DDB1 and CUL4 associated factor 8
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DPP4 dipeptidyl-peptidase 4
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
DZIP3 DAZ interacting zinc finger protein 3
EVI5 ecotropic viral integration site 5
FAM117A family with sequence similarity 117, member A
FANCF Fanconi anemia, complementation group F
FH fumarate hydratase
FOXN3 forkhead box N3
FSCN1 fascin actin-bundling protein 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GATAD2A GATA zinc finger domain containing 2A
GMCL1 germ cell-less, spermatogenesis associated 1
GPALPP1 GPALPP motifs containing 1
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
HLA-G major histocompatibility complex, class I, G
HNMT histamine N-methyltransferase
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOXA10 homeobox A10
ICK intestinal cell (MAK-like) kinase
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IQCG IQ motif containing G
IRF2 interferon regulatory factor 2
ITM2B integral membrane protein 2B
JAK2 Janus kinase 2
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KDM6A lysine (K)-specific demethylase 6A
KIAA0319L KIAA0319-like
KIDINS220 kinase D-interacting substrate, 220kDa
KLK10 kallikrein-related peptidase 10
LEPROT leptin receptor overlapping transcript
LITAF lipopolysaccharide-induced TNF factor
LPIN2 lipin 2
LYPD3 LY6/PLAUR domain containing 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDFIC MyoD family inhibitor domain containing
MPDZ multiple PDZ domain protein
NEK2 NIMA-related kinase 2
NNT nicotinamide nucleotide transhydrogenase
NPTXR neuronal pentraxin receptor
NRIP1 nuclear receptor interacting protein 1
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PIAS1 protein inhibitor of activated STAT, 1
PKP3 plakophilin 3
PODXL2 podocalyxin-like 2
POLM polymerase (DNA directed), mu
POMT2 protein-O-mannosyltransferase 2
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RPL23AP32 ribosomal protein L23a pseudogene 32
RRM1 ribonucleotide reductase M1
SCYL2 SCY1-like 2 (S. cerevisiae)
SENP6 SUMO1/sentrin specific peptidase 6
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SS18 synovial sarcoma translocation, chromosome 18
STOM stomatin
STXBP3 syntaxin binding protein 3
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBCD tubulin folding cofactor D
THOP1 thimet oligopeptidase 1
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TIMP4 TIMP metallopeptidase inhibitor 4
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNS2 tensin 2
TOR1AIP1 torsin A interacting protein 1
TRIM23 tripartite motif containing 23
WAPAL wings apart-like homolog (Drosophila)
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF358 zinc finger protein 358
ZNF552 zinc finger protein 552
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ANXA2P3 annexin A2 pseudogene 3
ASB13 ankyrin repeat and SOCS box containing 13
ASTE1 asteroid homolog 1 (Drosophila)
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCAS3 breast carcinoma amplified sequence 3
C6ORF47 chromosome 6 open reading frame 47
CAPN15 calpain 15
CARD8 caspase recruitment domain family, member 8
CGREF1 cell growth regulator with EF-hand domain 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN2 chloride channel, voltage-sensitive 2
COASY CoA synthase
CST4 cystatin S
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCL2 chemokine (C-X-C motif) ligand 2
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNMBP dynamin binding protein
EN2 engrailed homeobox 2
ERCC2 excision repair cross-complementation group 2
ETNK2 ethanolamine kinase 2
FAM53B family with sequence similarity 53, member B
FBXW12 F-box and WD repeat domain containing 12
FGD1 FYVE, RhoGEF and PH domain containing 1
FGGY FGGY carbohydrate kinase domain containing
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FUZ fuzzy planar cell polarity protein
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GLDC glycine dehydrogenase (decarboxylating)
GMIP GEM interacting protein
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GRAMD4 GRAM domain containing 4
GRPR gastrin-releasing peptide receptor
GRWD1 glutamate-rich WD repeat containing 1
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HLX H2.0-like homeobox
HOXC4 homeobox C4
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
JMJD4 jumonji domain containing 4
KDM5C lysine (K)-specific demethylase 5C
KIF3A kinesin family member 3A
KIFC3 kinesin family member C3
LAMC3 laminin, gamma 3
LMNB1 lamin B1
MAGEF1 melanoma antigen family F1
MCMBP minichromosome maintenance complex binding protein
MED9 mediator complex subunit 9
MOXD1 monooxygenase, DBH-like 1
MRPL52 mitochondrial ribosomal protein L52
NECAP2 NECAP endocytosis associated 2
NPR3 natriuretic peptide receptor 3
PC pyruvate carboxylase
PCSK7 proprotein convertase subtilisin/kexin type 7
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PILRB paired immunoglobin-like type 2 receptor beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PNRC1 proline-rich nuclear receptor coactivator 1
POTEKP POTE ankyrin domain family, member K, pseudogene
PXMP2 peroxisomal membrane protein 2, 22kDa
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM38 RNA binding motif protein 38
RIN1 Ras and Rab interactor 1
RPGR retinitis pigmentosa GTPase regulator
RUSC2 RUN and SH3 domain containing 2
SCAMP4 secretory carrier membrane protein 4
SH2D2A SH2 domain containing 2A
SH3GL1 SH3-domain GRB2-like 1
SIRT2 sirtuin 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMA4 glucuronidase, beta pseudogene
SPATA2L spermatogenesis associated 2-like
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAGLN3 transgelin 3
TBX19 T-box 19
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM104 transmembrane protein 104
TMEM242 transmembrane protein 242
TOM1 target of myb1 (chicken)
TPRA1 transmembrane protein, adipocyte asscociated 1
TSC22D4 TSC22 domain family, member 4
TTC26 tetratricopeptide repeat domain 26
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
URM1 ubiquitin related modifier 1
USP19 ubiquitin specific peptidase 19
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR19 WD repeat domain 19
ZBED8 zinc finger, BED-type containing 8
ZBTB22 zinc finger and BTB domain containing 22
ZNF668 zinc finger protein 668
ZNF747 zinc finger protein 747
ZNF85 zinc finger protein 85