acetohexamide-1707 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the acetohexamide-1707 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ALPK1 alpha-kinase 1
APOE apolipoprotein E
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ATP11A ATPase, class VI, type 11A
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BTF3P12 basic transcription factor 3 pseudogene 12
CD6 CD6 molecule
CD70 CD70 molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EGFR epidermal growth factor receptor
ETAA1 Ewing tumor-associated antigen 1
F11R F11 receptor
FLOT1 flotillin 1
FMO5 flavin containing monooxygenase 5
FMOD fibromodulin
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GJC2 gap junction protein, gamma 2, 47kDa
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GOSR2 golgi SNAP receptor complex member 2
GPATCH4 G patch domain containing 4
GPR107 G protein-coupled receptor 107
GSPT1 G1 to S phase transition 1
HFE hemochromatosis
HLA-C major histocompatibility complex, class I, C
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
ING1 inhibitor of growth family, member 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JUNB jun B proto-oncogene
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM4C lysine (K)-specific demethylase 4C
KIAA0355 KIAA0355
KMT2A lysine (K)-specific methyltransferase 2A
LIME1 Lck interacting transmembrane adaptor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MON2 MON2 homolog (S. cerevisiae)
MYBPC3 myosin binding protein C, cardiac
NOP16 NOP16 nucleolar protein
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G3 phospholipase A2, group III
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POU2F2 POU class 2 homeobox 2
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSG1 pregnancy specific beta-1-glycoprotein 1
PTRF polymerase I and transcript release factor
RCAN1 regulator of calcineurin 1
RER1 retention in endoplasmic reticulum sorting receptor 1
RPGR retinitis pigmentosa GTPase regulator
RPL10 ribosomal protein L10
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
RUFY3 RUN and FYVE domain containing 3
SAP30 Sin3A-associated protein, 30kDa
SASH1 SAM and SH3 domain containing 1
SCARB2 scavenger receptor class B, member 2
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMG7 SMG7 nonsense mediated mRNA decay factor
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSPN sarcospan
SSTR5 somatostatin receptor 5
STAT5B signal transducer and activator of transcription 5B
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SWAP70 SWAP switching B-cell complex 70kDa subunit
TADA2A transcriptional adaptor 2A
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TLR2 toll-like receptor 2
TLR5 toll-like receptor 5
TP53I11 tumor protein p53 inducible protein 11
TRIM2 tripartite motif containing 2
TTC23 tetratricopeptide repeat domain 23
TTLL5 tubulin tyrosine ligase-like family member 5
TUBA3C tubulin, alpha 3c
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VIPR2 vasoactive intestinal peptide receptor 2
WDR59 WD repeat domain 59
WDTC1 WD and tetratricopeptide repeats 1
ZBTB1 zinc finger and BTB domain containing 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZFPL1 zinc finger protein-like 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF329 zinc finger protein 329
ZNF532 zinc finger protein 532
ZNF639 zinc finger protein 639
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
AMPD2 adenosine monophosphate deaminase 2
ANKRD40 ankyrin repeat domain 40
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
ATP7B ATPase, Cu++ transporting, beta polypeptide
BCORL1 BCL6 corepressor-like 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
C4ORF29 chromosome 4 open reading frame 29
CAMK1 calcium/calmodulin-dependent protein kinase I
CDKL3 cyclin-dependent kinase-like 3
CIC capicua transcriptional repressor
CIDEB cell death-inducing DFFA-like effector b
CLCN2 chloride channel, voltage-sensitive 2
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CRY2 cryptochrome circadian clock 2
CSF1R colony stimulating factor 1 receptor
CTAGE9 CTAGE family, member 9
DBF4B DBF4 zinc finger B
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGKD diacylglycerol kinase, delta 130kDa
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNM1 dynamin 1
DYSF dysferlin
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELMO3 engulfment and cell motility 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM131A family with sequence similarity 131, member A
FAM204A family with sequence similarity 204, member A
FCHO1 FCH domain only 1
FCHSD2 FCH and double SH3 domains 2
FLRT3 fibronectin leucine rich transmembrane protein 3
FSTL3 follistatin-like 3 (secreted glycoprotein)
FURIN furin (paired basic amino acid cleaving enzyme)
GAA glucosidase, alpha; acid
GAS8 growth arrest-specific 8
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GRB7 growth factor receptor-bound protein 7
HIST1H2AJ histone cluster 1, H2aj
HMHA1 histocompatibility (minor) HA-1
HYI hydroxypyruvate isomerase (putative)
IDI2-AS1 IDI2 antisense RNA 1
IFI35 interferon-induced protein 35
IQSEC2 IQ motif and Sec7 domain 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0556 KIAA0556
KIZ kizuna centrosomal protein
KLHL25 kelch-like family member 25
KREMEN2 kringle containing transmembrane protein 2
LAMB3 laminin, beta 3
LOC390998 ribosomal protein L10 pseudogene
LRRC61 leucine rich repeat containing 61
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MYO1D myosin ID
NDE1 nudE neurodevelopment protein 1
NPIPB15 nuclear pore complex interacting protein family, member B15
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCBP4 poly(rC) binding protein 4
PCDHGB5 protocadherin gamma subfamily B, 5
PEX26 peroxisomal biogenesis factor 26
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLE polymerase (DNA directed), epsilon, catalytic subunit
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PTK6 protein tyrosine kinase 6
QTRT1 queuine tRNA-ribosyltransferase 1
RAB5B RAB5B, member RAS oncogene family
RIN1 Ras and Rab interactor 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF122 ring finger protein 122
RPL10L ribosomal protein L10-like
RSAD1 radical S-adenosyl methionine domain containing 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMA4 glucuronidase, beta pseudogene
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SYBU syntabulin (syntaxin-interacting)
SYCP2 synaptonemal complex protein 2
TAOK1 TAO kinase 1
TRAF2 TNF receptor-associated factor 2
TRIM25 tripartite motif containing 25
TSPYL2 TSPY-like 2
TUBA3D tubulin, alpha 3d
UNC119 unc-119 homolog (C. elegans)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
WDR46 WD repeat domain 46
ZNF365 zinc finger protein 365
ZNF442 zinc finger protein 442
ZNF787 zinc finger protein 787
ZNF816 zinc finger protein 816