acetohexamide-1829 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the acetohexamide-1829 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AGFG2 ArfGAP with FG repeats 2
ANKRD26 ankyrin repeat domain 26
APOL6 apolipoprotein L, 6
APP amyloid beta (A4) precursor protein
ATP10D ATPase, class V, type 10D
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
C9ORF156 chromosome 9 open reading frame 156
CAMTA2 calmodulin binding transcription activator 2
CCDC88C coiled-coil domain containing 88C
CDC25C cell division cycle 25C
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CPD carboxypeptidase D
CXCL12 chemokine (C-X-C motif) ligand 12
CYLD cylindromatosis (turban tumor syndrome)
DBT dihydrolipoamide branched chain transacylase E2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFR3A EFR3 homolog A (S. cerevisiae)
EML4 echinoderm microtubule associated protein like 4
ESR1 estrogen receptor 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
HIC2 hypermethylated in cancer 2
HIST1H2BJ histone cluster 1, H2bj
HOXC5 homeobox C5
IFI27 interferon, alpha-inducible protein 27
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFITM1 interferon induced transmembrane protein 1
IGF1R insulin-like growth factor 1 receptor
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRF9 interferon regulatory factor 9
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KCTD17 potassium channel tetramerization domain containing 17
KIAA0319L KIAA0319-like
KLHL20 kelch-like family member 20
KMT2A lysine (K)-specific methyltransferase 2A
LARP7 La ribonucleoprotein domain family, member 7
LEF1 lymphoid enhancer-binding factor 1
LOC644450 uncharacterized LOC644450
MCC mutated in colorectal cancers
MED28 mediator complex subunit 28
MEGF6 multiple EGF-like-domains 6
MINK1 misshapen-like kinase 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MPDZ multiple PDZ domain protein
MSRB2 methionine sulfoxide reductase B2
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
NOD1 nucleotide-binding oligomerization domain containing 1
NUP205 nucleoporin 205kDa
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
PADI1 peptidyl arginine deiminase, type I
PARVA parvin, alpha
PCDH1 protocadherin 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLD2 phospholipase D2
PLK3 polo-like kinase 3
PLSCR1 phospholipid scramblase 1
PLXND1 plexin D1
POLL polymerase (DNA directed), lambda
PRDM2 PR domain containing 2, with ZNF domain
PXMP4 peroxisomal membrane protein 4, 24kDa
PYY peptide YY
RAB6A RAB6A, member RAS oncogene family
RNASEH2B ribonuclease H2, subunit B
RPH3AL rabphilin 3A-like (without C2 domains)
RSAD2 radical S-adenosyl methionine domain containing 2
SEC63 SEC63 homolog (S. cerevisiae)
SFTPB surfactant protein B
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SP110 SP110 nuclear body protein
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SRSF1 serine/arginine-rich splicing factor 1
STAT1 signal transducer and activator of transcription 1, 91kDa
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TCF4 transcription factor 4
TEX40 testis expressed 40
THRB thyroid hormone receptor, beta
TMEM180 transmembrane protein 180
TRAF3IP2 TRAF3 interacting protein 2
TRIO trio Rho guanine nucleotide exchange factor
UNC5B unc-5 homolog B (C. elegans)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP18 ubiquitin specific peptidase 18
UTRN utrophin
WDR1 WD repeat domain 1
WNT2 wingless-type MMTV integration site family member 2
ZNF286A zinc finger protein 286A
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARMC6 armadillo repeat containing 6
ATP11B ATPase, class VI, type 11B
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCAS3 breast carcinoma amplified sequence 3
BRIX1 BRX1, biogenesis of ribosomes
C1ORF115 chromosome 1 open reading frame 115
C6ORF47 chromosome 6 open reading frame 47
CCP110 centriolar coiled coil protein 110kDa
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CENPT centromere protein T
CEP112 centrosomal protein 112kDa
CHST10 carbohydrate sulfotransferase 10
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CYB5R3 cytochrome b5 reductase 3
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAF1 DEAF1 transcription factor
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DMBT1 deleted in malignant brain tumors 1
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ERCC5 excision repair cross-complementation group 5
ERF Ets2 repressor factor
ETV4 ets variant 4
EXO1 exonuclease 1
F2R coagulation factor II (thrombin) receptor
FAM53B family with sequence similarity 53, member B
FBXW12 F-box and WD repeat domain containing 12
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIRA histone cell cycle regulator
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
IMPAD1 inositol monophosphatase domain containing 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA0894 KIAA0894 protein
KRT15 keratin 15, type I
LARP6 La ribonucleoprotein domain family, member 6
MAN2B2 mannosidase, alpha, class 2B, member 2
MIR22HG MIR22 host gene
MKS1 Meckel syndrome, type 1
MXD3 MAX dimerization protein 3
MYO1D myosin ID
NECAB3 N-terminal EF-hand calcium binding protein 3
NHLRC2 NHL repeat containing 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUPR1 nuclear protein, transcriptional regulator, 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PELI1 pellino E3 ubiquitin protein ligase 1
PILRB paired immunoglobin-like type 2 receptor beta
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLA2G12A phospholipase A2, group XIIA
PLA2G15 phospholipase A2, group XV
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POMT1 protein-O-mannosyltransferase 1
POR P450 (cytochrome) oxidoreductase
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPT2 palmitoyl-protein thioesterase 2
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTCD1 pentatricopeptide repeat domain 1
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM28 RNA binding motif protein 28
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RNF38 ring finger protein 38
ROGDI rogdi homolog (Drosophila)
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
S100A4 S100 calcium binding protein A4
SELENBP1 selenium binding protein 1
SERINC5 serine incorporator 5
SH3GL1 SH3-domain GRB2-like 1
SIAH2 siah E3 ubiquitin protein ligase 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLMO2 slowmo homolog 2 (Drosophila)
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPAG4 sperm associated antigen 4
SPRY2 sprouty homolog 2 (Drosophila)
SREBF1 sterol regulatory element binding transcription factor 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STIM1 stromal interaction molecule 1
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TMEM104 transmembrane protein 104
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAPPC11 trafficking protein particle complex 11
TSC1 tuberous sclerosis 1
UBIAD1 UbiA prenyltransferase domain containing 1
UFSP2 UFM1-specific peptidase 2
VASP vasodilator-stimulated phosphoprotein
ZBED1 zinc finger, BED-type containing 1
ZCCHC10 zinc finger, CCHC domain containing 10
ZMAT5 zinc finger, matrin-type 5
ZNF324 zinc finger protein 324
ZSCAN16 zinc finger and SCAN domain containing 16