acetyl-CoA metabolic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. (Gene Ontology, GO_0006084)
External Link http://amigo.geneontology.org/amigo/term/GO:0006084
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Genes

18 genes participating in the acetyl-CoA metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
ACLY ATP citrate lyase
ACOT12 acyl-CoA thioesterase 12
ACSS1 acyl-CoA synthetase short-chain family member 1
ACSS2 acyl-CoA synthetase short-chain family member 2
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
MLYCD malonyl-CoA decarboxylase
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8
PMVK phosphomevalonate kinase
PPCS phosphopantothenoylcysteine synthetase
SOAT1 sterol O-acyltransferase 1
TDO2 tryptophan 2,3-dioxygenase