acetylsalicylic acid-315 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the acetylsalicylic acid-315 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACAA2 acetyl-CoA acyltransferase 2
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
APOLD1 apolipoprotein L domain containing 1
ARFRP1 ADP-ribosylation factor related protein 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASCL3 achaete-scute family bHLH transcription factor 3
ASIC4 acid sensing (proton gated) ion channel family member 4
CA5B carbonic anhydrase VB, mitochondrial
CCDC87 coiled-coil domain containing 87
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD247 CD247 molecule
CD5 CD5 molecule
CDH22 cadherin 22, type 2
CFB complement factor B
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIO3 deiodinase, iodothyronine, type III
DNAH3 dynein, axonemal, heavy chain 3
DSCR4 Down syndrome critical region 4
E2F1 E2F transcription factor 1
EFCAB1 EF-hand calcium binding domain 1
EML2 echinoderm microtubule associated protein like 2
ERCC2 excision repair cross-complementation group 2
FBXO31 F-box protein 31
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FNDC3A fibronectin type III domain containing 3A
FOXF1 forkhead box F1
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GLG1 golgi glycoprotein 1
GMIP GEM interacting protein
GP2 glycoprotein 2 (zymogen granule membrane)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HMP19 HMP19 protein
HOXB1 homeobox B1
HOXC5 homeobox C5
HPX hemopexin
HUS1 HUS1 checkpoint homolog (S. pombe)
IL10 interleukin 10
IL5RA interleukin 5 receptor, alpha
ING4 inhibitor of growth family, member 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA1614 KIAA1614
KLHL1 kelch-like family member 1
LINC00652 long intergenic non-protein coding RNA 652
LOC441601 septin 7 pseudogene
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRK1 leucine-rich repeat kinase 1
LRRN3 leucine rich repeat neuronal 3
LUZP1 leucine zipper protein 1
MAGEA3 melanoma antigen family A3
MAST3 microtubule associated serine/threonine kinase 3
MATN1 matrilin 1, cartilage matrix protein
MC3R melanocortin 3 receptor
MCHR1 melanin-concentrating hormone receptor 1
MGC2889 uncharacterized protein MGC2889
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OPCML opioid binding protein/cell adhesion molecule-like
PAX1 paired box 1
PAX8 paired box 8
PDCD1 programmed cell death 1
PNMT phenylethanolamine N-methyltransferase
PRDM14 PR domain containing 14
PSAT1 phosphoserine aminotransferase 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
RARB retinoic acid receptor, beta
RBP1 retinol binding protein 1, cellular
REPS1 RALBP1 associated Eps domain containing 1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
SBNO1 strawberry notch homolog 1 (Drosophila)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMO smoothened, frizzled class receptor
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STAB2 stabilin 2
SYN1 synapsin I
TGM3 transglutaminase 3
TMEM176A transmembrane protein 176A
TMSB4Y thymosin beta 4, Y-linked
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNS4 tensin 4
TRAC T cell receptor alpha constant
TRAF3IP2 TRAF3 interacting protein 2
ULK2 unc-51 like autophagy activating kinase 2
UNC5B unc-5 homolog B (C. elegans)
VIPR2 vasoactive intestinal peptide receptor 2
VTN vitronectin
WIZ widely interspaced zinc finger motifs
ZNF460 zinc finger protein 460

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACBD4 acyl-CoA binding domain containing 4
ALPK1 alpha-kinase 1
AMN amnion associated transmembrane protein
ANXA2P2 annexin A2 pseudogene 2
AQP8 aquaporin 8
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
AXIN1 axin 1
AZI2 5-azacytidine induced 2
BPGM 2,3-bisphosphoglycerate mutase
C10ORF88 chromosome 10 open reading frame 88
CA5BP1 carbonic anhydrase VB pseudogene 1
CAMKMT calmodulin-lysine N-methyltransferase
CBX7 chromobox homolog 7
CBX8 chromobox homolog 8
CCDC121 coiled-coil domain containing 121
CCDC82 coiled-coil domain containing 82
CCDC85C coiled-coil domain containing 85C
CD180 CD180 molecule
CD38 CD38 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK6 cyclin-dependent kinase 6
CHRM4 cholinergic receptor, muscarinic 4
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLCN6 chloride channel, voltage-sensitive 6
CLEC4E C-type lectin domain family 4, member E
CLTCL1 clathrin, heavy chain-like 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYSLTR2 cysteinyl leukotriene receptor 2
DMBT1 deleted in malignant brain tumors 1
DNAL4 dynein, axonemal, light chain 4
DUSP2 dual specificity phosphatase 2
ELOVL4 ELOVL fatty acid elongase 4
EXOSC9 exosome component 9
F3 coagulation factor III (thromboplastin, tissue factor)
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GRM2 glutamate receptor, metabotropic 2
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
H2AFY2 H2A histone family, member Y2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
IQGAP2 IQ motif containing GTPase activating protein 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIFAP3 kinesin-associated protein 3
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHL3 kelch-like family member 3
KREMEN2 kringle containing transmembrane protein 2
LENEP lens epithelial protein
LGALS13 lectin, galactoside-binding, soluble, 13
LHX6 LIM homeobox 6
LIN7A lin-7 homolog A (C. elegans)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
METTL16 methyltransferase like 16
MFAP2 microfibrillar-associated protein 2
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PF4 platelet factor 4
PHC1 polyhomeotic homolog 1 (Drosophila)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRSS2 protease, serine, 2 (trypsin 2)
RAP1A RAP1A, member of RAS oncogene family
RCVRN recoverin
RECQL4 RecQ protein-like 4
RHOH ras homolog family member H
RNF25 ring finger protein 25
ROPN1B rhophilin associated tail protein 1B
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SHARPIN SHANK-associated RH domain interactor
SIL1 SIL1 nucleotide exchange factor
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMIM14 small integral membrane protein 14
SPINK5 serine peptidase inhibitor, Kazal type 5
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBC1D29 TBC1 domain family, member 29
TBL1Y transducin (beta)-like 1, Y-linked
TM4SF5 transmembrane 4 L six family member 5
TOLLIP toll interacting protein
TTC33 tetratricopeptide repeat domain 33
UMOD uromodulin
UNC93B1 unc-93 homolog B1 (C. elegans)
WDR91 WD repeat domain 91
WNT2 wingless-type MMTV integration site family member 2
WT1-AS WT1 antisense RNA
WWC2 WW and C2 domain containing 2
XAF1 XIAP associated factor 1
ZFP36 ZFP36 ring finger protein
ZXDC ZXD family zinc finger C