acetylsalicylic acid-4428 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the acetylsalicylic acid-4428 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE2 angiotensin I converting enzyme 2
ACTN2 actinin, alpha 2
ADGRA2 adhesion G protein-coupled receptor A2
AGTR1 angiotensin II receptor, type 1
APOL3 apolipoprotein L, 3
ARID4B AT rich interactive domain 4B (RBP1-like)
ARSA arylsulfatase A
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BEGAIN brain-enriched guanylate kinase-associated
C9ORF116 chromosome 9 open reading frame 116
CACFD1 calcium channel flower domain containing 1
CASS4 Cas scaffolding protein family member 4
CCL19 chemokine (C-C motif) ligand 19
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CDON cell adhesion associated, oncogene regulated
CEP41 centrosomal protein 41kDa
CHAT choline O-acetyltransferase
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLTCL1 clathrin, heavy chain-like 1
CPZ carboxypeptidase Z
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DHRS12 dehydrogenase/reductase (SDR family) member 12
DKFZP434C153 DKFZP434C153 protein
DLC1 DLC1 Rho GTPase activating protein
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOK3 docking protein 3
DPYSL4 dihydropyrimidinase-like 4
DTX3 deltex 3, E3 ubiquitin ligase
ENG endoglin
EYA4 EYA transcriptional coactivator and phosphatase 4
FABP7 fatty acid binding protein 7, brain
FGF3 fibroblast growth factor 3
FGF4 fibroblast growth factor 4
FLT3LG fms-related tyrosine kinase 3 ligand
GLI2 GLI family zinc finger 2
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPATCH4 G patch domain containing 4
GRIP2 glutamate receptor interacting protein 2
GRK5 G protein-coupled receptor kinase 5
GRM6 glutamate receptor, metabotropic 6
HAO2 hydroxyacid oxidase 2 (long chain)
HIST1H4F histone cluster 1, H4f
HOXC11 homeobox C11
HP haptoglobin
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IL1R1 interleukin 1 receptor, type I
IRF8 interferon regulatory factor 8
KERA keratocan
KIF1A kinesin family member 1A
KIF1C kinesin family member 1C
KLF13 Kruppel-like factor 13
LDAH lipid droplet associated hydrolase
LHB luteinizing hormone beta polypeptide
MAGEA5 melanoma antigen family A5
MAP2K7 mitogen-activated protein kinase kinase 7
MCF2L MCF.2 cell line derived transforming sequence-like
MEGF8 multiple EGF-like-domains 8
NDNF neuron-derived neurotrophic factor
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
OAZ3 ornithine decarboxylase antizyme 3
PAPPA2 pappalysin 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM5 PDZ and LIM domain 5
PICALM phosphatidylinositol binding clathrin assembly protein
PPP5C protein phosphatase 5, catalytic subunit
PRF1 perforin 1 (pore forming protein)
PTGIS prostaglandin I2 (prostacyclin) synthase
RAB36 RAB36, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RIN3 Ras and Rab interactor 3
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SAP30 Sin3A-associated protein, 30kDa
SIRPA signal-regulatory protein alpha
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLIT1 slit homolog 1 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNPH syntaphilin
SOX10 SRY (sex determining region Y)-box 10
SOX2 SRY (sex determining region Y)-box 2
SRCAP Snf2-related CREBBP activator protein
STAT5A signal transducer and activator of transcription 5A
TAOK1 TAO kinase 1
TECPR2 tectonin beta-propeller repeat containing 2
TEF thyrotrophic embryonic factor
TRD T cell receptor delta locus
TRIM10 tripartite motif containing 10
TRO trophinin
TRPV4 transient receptor potential cation channel, subfamily V, member 4
VAMP5 vesicle-associated membrane protein 5
VCX2 variable charge, X-linked 2
VPRBP Vpr (HIV-1) binding protein
WNT8B wingless-type MMTV integration site family, member 8B
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ALPK1 alpha-kinase 1
ANKH ANKH inorganic pyrophosphate transport regulator
ANXA2P1 annexin A2 pseudogene 1
ARHGAP24 Rho GTPase activating protein 24
ARID3A AT rich interactive domain 3A (BRIGHT-like)
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BEX1 brain expressed, X-linked 1
BMP4 bone morphogenetic protein 4
BMPR1B bone morphogenetic protein receptor, type IB
CCP110 centriolar coiled coil protein 110kDa
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CENPJ centromere protein J
CFAP45 cilia and flagella associated protein 45
CLCN6 chloride channel, voltage-sensitive 6
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DLK2 delta-like 2 homolog (Drosophila)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNM3 dynamin 3
DTX2 deltex 2, E3 ubiquitin ligase
EDIL3 EGF-like repeats and discoidin I-like domains 3
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBRS fibrosin
FBXL15 F-box and leucine-rich repeat protein 15
FKBP5 FK506 binding protein 5
FRS2 fibroblast growth factor receptor substrate 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRTP1 growth hormone regulated TBC protein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC11 histone deacetylase 11
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
HIST1H4C histone cluster 1, H4c
HOXA7 homeobox A7
HOXC5 homeobox C5
HSPA1L heat shock 70kDa protein 1-like
IL12RB1 interleukin 12 receptor, beta 1
IQSEC2 IQ motif and Sec7 domain 2
IRAK4 interleukin-1 receptor-associated kinase 4
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCTD17 potassium channel tetramerization domain containing 17
KLK7 kallikrein-related peptidase 7
LINC00597 long intergenic non-protein coding RNA 597
MGP matrix Gla protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MILR1 mast cell immunoglobulin-like receptor 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MN1 meningioma (disrupted in balanced translocation) 1
MOCS1 molybdenum cofactor synthesis 1
MT1M metallothionein 1M
MTA2 metastasis associated 1 family, member 2
MTCP1 mature T-cell proliferation 1
MVD mevalonate (diphospho) decarboxylase
NCALD neurocalcin delta
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPR2 natriuretic peptide receptor 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OSR2 odd-skipped related transciption factor 2
PHC1 polyhomeotic homolog 1 (Drosophila)
PRAMEF11 PRAME family member 11
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SELL selectin L
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC12A8 solute carrier family 12, member 8
SLC22A14 solute carrier family 22, member 14
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC46A3 solute carrier family 46, member 3
SLITRK5 SLIT and NTRK-like family, member 5
SMO smoothened, frizzled class receptor
SOSTDC1 sclerostin domain containing 1
SPATA2L spermatogenesis associated 2-like
SPTBN2 spectrin, beta, non-erythrocytic 2
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRD5A3 steroid 5 alpha-reductase 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SYT17 synaptotagmin XVII
TH tyrosine hydroxylase
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM53 transmembrane protein 53
TRAF5 TNF receptor-associated factor 5
TTLL7 tubulin tyrosine ligase-like family member 7
TUBA3D tubulin, alpha 3d
UBTD1 ubiquitin domain containing 1
UNC93B1 unc-93 homolog B1 (C. elegans)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WNT16 wingless-type MMTV integration site family, member 16
ZNF222 zinc finger protein 222
ZNF280B zinc finger protein 280B
ZNF573 zinc finger protein 573
ZNF639 zinc finger protein 639
ZNF667 zinc finger protein 667
ZNF747 zinc finger protein 747
ZSCAN2 zinc finger and SCAN domain containing 2