acetylsalicylic acid-5564 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the acetylsalicylic acid-5564 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
AQP4 aquaporin 4
ARHGAP1 Rho GTPase activating protein 1
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ART1 ADP-ribosyltransferase 1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
CA5B carbonic anhydrase VB, mitochondrial
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CADM4 cell adhesion molecule 4
CALCR calcitonin receptor
CAMK1 calcium/calmodulin-dependent protein kinase I
CASS4 Cas scaffolding protein family member 4
CENPO centromere protein O
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CIDEB cell death-inducing DFFA-like effector b
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DAPK1 death-associated protein kinase 1
DENND3 DENN/MADD domain containing 3
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DLX2 distal-less homeobox 2
DSC3 desmocollin 3
DUOX1 dual oxidase 1
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ELN elastin
EPHX2 epoxide hydrolase 2, cytoplasmic
EPX eosinophil peroxidase
ESR1 estrogen receptor 1
FBLN1 fibulin 1
FBN2 fibrillin 2
FCAR Fc fragment of IgA receptor
FGFBP1 fibroblast growth factor binding protein 1
FPR1 formyl peptide receptor 1
FRMPD1 FERM and PDZ domain containing 1
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GRIP2 glutamate receptor interacting protein 2
HNF4A hepatocyte nuclear factor 4, alpha
HOXD3 homeobox D3
HRASLS HRAS-like suppressor
IRF2BP1 interferon regulatory factor 2 binding protein 1
KAZN kazrin, periplakin interacting protein
KLHL25 kelch-like family member 25
KRT31 keratin 31, type I
LAMA4 laminin, alpha 4
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LY86 lymphocyte antigen 86
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MID1 midline 1
MUC6 mucin 6, oligomeric mucus/gel-forming
MUC8 mucin 8
NDN necdin, melanoma antigen (MAGE) family member
NOP14-AS1 NOP14 antisense RNA 1
NOV nephroblastoma overexpressed
NR6A1 nuclear receptor subfamily 6, group A, member 1
NTM neurotrimin
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
PCDHA10 protocadherin alpha 10
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PLXNA2 plexin A2
PLXNB1 plexin B1
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PRELP proline/arginine-rich end leucine-rich repeat protein
PTCH1 patched 1
PTCRA pre T-cell antigen receptor alpha
PTGDR2 prostaglandin D2 receptor 2
RAB40C RAB40C, member RAS oncogene family
RGS7 regulator of G-protein signaling 7
RPL10 ribosomal protein L10
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RUNX1 runt-related transcription factor 1
S100A2 S100 calcium binding protein A2
SAG S-antigen; retina and pineal gland (arrestin)
SFTPB surfactant protein B
SIGLEC7 sialic acid binding Ig-like lectin 7
SIRPB1 signal-regulatory protein beta 1
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SPN sialophorin
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
TAPBPL TAP binding protein-like
TM4SF1 transmembrane 4 L six family member 1
TPMT thiopurine S-methyltransferase
TRIM9 tripartite motif containing 9
TSNAXIP1 translin-associated factor X interacting protein 1
TTC38 tetratricopeptide repeat domain 38
TUBA3C tubulin, alpha 3c
WNT16 wingless-type MMTV integration site family, member 16
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZEB1 zinc finger E-box binding homeobox 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF415 zinc finger protein 415

decreased expression

Symbol Name
AEN apoptosis enhancing nuclease
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
ATG9A autophagy related 9A
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBS7 Bardet-Biedl syndrome 7
BGLAP bone gamma-carboxyglutamate (gla) protein
C11ORF80 chromosome 11 open reading frame 80
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA11 carbonic anhydrase XI
CA5BP1 carbonic anhydrase VB pseudogene 1
CCDC9 coiled-coil domain containing 9
CCP110 centriolar coiled coil protein 110kDa
CHKB choline kinase beta
CTC1 CTS telomere maintenance complex component 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DSN1 DSN1, MIS12 kinetochore complex component
EDC4 enhancer of mRNA decapping 4
EIF5A2 eukaryotic translation initiation factor 5A2
ERCC5 excision repair cross-complementation group 5
ETAA1 Ewing tumor-associated antigen 1
EVPL envoplakin
EXO5 exonuclease 5
FAM120C family with sequence similarity 120C
FAM204A family with sequence similarity 204, member A
FBRS fibrosin
FBXW12 F-box and WD repeat domain containing 12
FKBP14 FK506 binding protein 14, 22 kDa
FSTL3 follistatin-like 3 (secreted glycoprotein)
GATA6 GATA binding protein 6
GATAD2A GATA zinc finger domain containing 2A
GLS2 glutaminase 2 (liver, mitochondrial)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GNL1 guanine nucleotide binding protein-like 1
HOXA4 homeobox A4
IL4R interleukin 4 receptor
KATNBL1 katanin p80 subunit B-like 1
KCTD7 potassium channel tetramerization domain containing 7
LAMA5 laminin, alpha 5
LAMB3 laminin, beta 3
LIN7A lin-7 homolog A (C. elegans)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBTD1 mbt domain containing 1
MCRS1 microspherule protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFE2L3 nuclear factor, erythroid 2-like 3
NT5DC3 5'-nucleotidase domain containing 3
OSGIN1 oxidative stress induced growth inhibitor 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCDHB8 protocadherin beta 8
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PKN1 protein kinase N1
PLA2G3 phospholipase A2, group III
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PNPLA6 patatin-like phospholipase domain containing 6
PODXL2 podocalyxin-like 2
POMT2 protein-O-mannosyltransferase 2
PRODH proline dehydrogenase (oxidase) 1
PRPH peripherin
PRSS16 protease, serine, 16 (thymus)
PTK6 protein tyrosine kinase 6
PTPRU protein tyrosine phosphatase, receptor type, U
QTRT1 queuine tRNA-ribosyltransferase 1
RIN2 Ras and Rab interactor 2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL23AP32 ribosomal protein L23a pseudogene 32
SAV1 salvador family WW domain containing protein 1
SCRIB scribbled planar cell polarity protein
SDC3 syndecan 3
SGCE sarcoglycan, epsilon
SGMS1 sphingomyelin synthase 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC38A10 solute carrier family 38, member 10
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNAI2 snail family zinc finger 2
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STX1A syntaxin 1A (brain)
SYNGR3 synaptogyrin 3
TBC1D17 TBC1 domain family, member 17
TBCCD1 TBCC domain containing 1
TICAM1 toll-like receptor adaptor molecule 1
TMEM127 transmembrane protein 127
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRAPPC13 trafficking protein particle complex 13
TTC33 tetratricopeptide repeat domain 33
WDR76 WD repeat domain 76
ZNF573 zinc finger protein 573