acetylsalicylic acid-6964 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the acetylsalicylic acid-6964 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACSL4 acyl-CoA synthetase long-chain family member 4
AGMAT agmatine ureohydrolase (agmatinase)
AGRN agrin
ANGPTL7 angiopoietin-like 7
ANXA2P3 annexin A2 pseudogene 3
ARHGAP32 Rho GTPase activating protein 32
BCAM basal cell adhesion molecule (Lutheran blood group)
BIN1 bridging integrator 1
C16ORF45 chromosome 16 open reading frame 45
C22ORF46 chromosome 22 open reading frame 46
C7ORF43 chromosome 7 open reading frame 43
CACFD1 calcium channel flower domain containing 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCPG1 cell cycle progression 1
COL4A5 collagen, type IV, alpha 5
CPNE7 copine VII
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
ELOVL4 ELOVL fatty acid elongase 4
F3 coagulation factor III (thromboplastin, tissue factor)
FAM131A family with sequence similarity 131, member A
FBXL2 F-box and leucine-rich repeat protein 2
FGF4 fibroblast growth factor 4
FN1 fibronectin 1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GHRHR growth hormone releasing hormone receptor
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GOSR2 golgi SNAP receptor complex member 2
HES2 hes family bHLH transcription factor 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HPS1 Hermansky-Pudlak syndrome 1
IQSEC2 IQ motif and Sec7 domain 2
IRF6 interferon regulatory factor 6
JAKMIP2 janus kinase and microtubule interacting protein 2
KIF13B kinesin family member 13B
KLHL25 kelch-like family member 25
LAMB3 laminin, beta 3
LHX1 LIM homeobox 1
LINC01587 long intergenic non-protein coding RNA 1587
LRRC14 leucine rich repeat containing 14
LST1 leukocyte specific transcript 1
LTBP4 latent transforming growth factor beta binding protein 4
MAP4 microtubule-associated protein 4
MBD1 methyl-CpG binding domain protein 1
MKL1 megakaryoblastic leukemia (translocation) 1
MLANA melan-A
MTM1 myotubularin 1
MYL10 myosin, light chain 10, regulatory
NIPAL2 NIPA-like domain containing 2
NMT2 N-myristoyltransferase 2
NPFFR1 neuropeptide FF receptor 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
OGFR opioid growth factor receptor
OPTN optineurin
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PAX8 paired box 8
PCGF2 polycomb group ring finger 2
PELI1 pellino E3 ubiquitin protein ligase 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PKNOX1 PBX/knotted 1 homeobox 1
PLCG1 phospholipase C, gamma 1
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PSAT1 phosphoserine aminotransferase 1
PTPRE protein tyrosine phosphatase, receptor type, E
QKI QKI, KH domain containing, RNA binding
RARA retinoic acid receptor, alpha
RGS2 regulator of G-protein signaling 2
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF2 ring finger protein 2
RNF24 ring finger protein 24
RPL7 ribosomal protein L7
RRBP1 ribosome binding protein 1
RSL1D1 ribosomal L1 domain containing 1
RTEL1 regulator of telomere elongation helicase 1
SH3BP2 SH3-domain binding protein 2
SOCS1 suppressor of cytokine signaling 1
SOX13 SRY (sex determining region Y)-box 13
SPRR1A small proline-rich protein 1A
SREBF2 sterol regulatory element binding transcription factor 2
STX1A syntaxin 1A (brain)
TBX19 T-box 19
TK2 thymidine kinase 2, mitochondrial
TMOD1 tropomodulin 1
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNS2 tensin 2
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UPK2 uroplakin 2
USF2 upstream transcription factor 2, c-fos interacting
WSCD1 WSC domain containing 1
ZER1 zyg-11 related, cell cycle regulator
ZFHX4 zinc finger homeobox 4
ZNF16 zinc finger protein 16
ZNF571 zinc finger protein 571

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADAM15 ADAM metallopeptidase domain 15
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
AXIN1 axin 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BPHL biphenyl hydrolase-like (serine hydrolase)
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF112 chromosome 1 open reading frame 112
C21ORF91 chromosome 21 open reading frame 91
C4ORF29 chromosome 4 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
CCDC25 coiled-coil domain containing 25
CCDC85C coiled-coil domain containing 85C
CCNT1 cyclin T1
CENPJ centromere protein J
CEP131 centrosomal protein 131kDa
CISH cytokine inducible SH2-containing protein
CORO2A coronin, actin binding protein, 2A
DHRS11 dehydrogenase/reductase (SDR family) member 11
DSCR3 Down syndrome critical region 3
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EAF2 ELL associated factor 2
EDC3 enhancer of mRNA decapping 3
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
F8 coagulation factor VIII, procoagulant component
FKBP10 FK506 binding protein 10, 65 kDa
FOSL1 FOS-like antigen 1
FSD1 fibronectin type III and SPRY domain containing 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GAN gigaxonin
GLTP glycolipid transfer protein
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2I general transcription factor IIi
HCFC2 host cell factor C2
HIST1H1D histone cluster 1, H1d
HIST1H2AG histone cluster 1, H2ag
HMGB3P1 high mobility group box 3 pseudogene 1
HYAL2 hyaluronoglucosaminidase 2
INF2 inverted formin, FH2 and WH2 domain containing
IREB2 iron-responsive element binding protein 2
JMJD4 jumonji domain containing 4
KCTD15 potassium channel tetramerization domain containing 15
KIAA0232 KIAA0232
KIAA0922 KIAA0922
KRBOX4 KRAB box domain containing 4
LIN7B lin-7 homolog B (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LRP3 low density lipoprotein receptor-related protein 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEIS1 Meis homeobox 1
MPST mercaptopyruvate sulfurtransferase
NDE1 nudE neurodevelopment protein 1
NECAP2 NECAP endocytosis associated 2
NOTCH1 notch 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRBF2 nuclear receptor binding factor 2
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PLA2G15 phospholipase A2, group XV
PLEK2 pleckstrin 2
POLI polymerase (DNA directed) iota
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAB4B RAB4B, member RAS oncogene family
RBM41 RNA binding motif protein 41
RECQL4 RecQ protein-like 4
RFTN1 raftlin, lipid raft linker 1
RNF170 ring finger protein 170
RNF25 ring finger protein 25
RPL13P5 ribosomal protein L13 pseudogene 5
SH2B3 SH2B adaptor protein 3
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SNIP1 Smad nuclear interacting protein 1
SOX3 SRY (sex determining region Y)-box 3
SPIDR scaffolding protein involved in DNA repair
SPRYD7 SPRY domain containing 7
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THAP4 THAP domain containing 4
THOP1 thimet oligopeptidase 1
TMEM51 transmembrane protein 51
TMEM57 transmembrane protein 57
TRAPPC13 trafficking protein particle complex 13
TRAPPC6A trafficking protein particle complex 6A
TRIM25 tripartite motif containing 25
TSPAN1 tetraspanin 1
TSPYL2 TSPY-like 2
UNC119 unc-119 homolog (C. elegans)
ZBTB3 zinc finger and BTB domain containing 3
ZNF211 zinc finger protein 211
ZNF253 zinc finger protein 253
ZNF280D zinc finger protein 280D
ZNF668 zinc finger protein 668
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2