acetylsalicylic acid-984 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the acetylsalicylic acid-984 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ACVR1B activin A receptor, type IB
ADGRL3 adhesion G protein-coupled receptor L3
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGAP35 Rho GTPase activating protein 35
ARSB arylsulfatase B
ASTN1 astrotactin 1
ATP11A ATPase, class VI, type 11A
B9D2 B9 protein domain 2
C9ORF16 chromosome 9 open reading frame 16
CABIN1 calcineurin binding protein 1
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMK4 calcium/calmodulin-dependent protein kinase IV
CC2D1A coiled-coil and C2 domain containing 1A
CCHCR1 coiled-coil alpha-helical rod protein 1
CLCF1 cardiotrophin-like cytokine factor 1
COL3A1 collagen, type III, alpha 1
COL6A1 collagen, type VI, alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
CROCC ciliary rootlet coiled-coil, rootletin
CSHL1 chorionic somatomammotropin hormone-like 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCT dopachrome tautomerase
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIEXF digestive organ expansion factor homolog (zebrafish)
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DTNA dystrobrevin, alpha
DVL2 dishevelled segment polarity protein 2
ELOVL5 ELOVL fatty acid elongase 5
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM184A family with sequence similarity 184, member A
FCGBP Fc fragment of IgG binding protein
FMO5 flavin containing monooxygenase 5
GRIK5 glutamate receptor, ionotropic, kainate 5
HLA-J major histocompatibility complex, class I, J (pseudogene)
HSPA1L heat shock 70kDa protein 1-like
HYAL3 hyaluronoglucosaminidase 3
ICOSLG inducible T-cell co-stimulator ligand
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IRS4 insulin receptor substrate 4
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB5 integrin, beta 5
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KREMEN2 kringle containing transmembrane protein 2
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTBP4 latent transforming growth factor beta binding protein 4
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MED16 mediator complex subunit 16
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MTAP methylthioadenosine phosphorylase
MXD4 MAX dimerization protein 4
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NR6A1 nuclear receptor subfamily 6, group A, member 1
NREP neuronal regeneration related protein
PBX2 pre-B-cell leukemia homeobox 2
PDE12 phosphodiesterase 12
PDE4DIP phosphodiesterase 4D interacting protein
PDGFB platelet-derived growth factor beta polypeptide
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHF8 PHD finger protein 8
PICALM phosphatidylinositol binding clathrin assembly protein
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POMT2 protein-O-mannosyltransferase 2
PPP5C protein phosphatase 5, catalytic subunit
PSD4 pleckstrin and Sec7 domain containing 4
RAD54B RAD54 homolog B (S. cerevisiae)
RGS12 regulator of G-protein signaling 12
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPL10 ribosomal protein L10
SBNO2 strawberry notch homolog 2 (Drosophila)
SGCE sarcoglycan, epsilon
SH3BP2 SH3-domain binding protein 2
SIM2 single-minded family bHLH transcription factor 2
SMC4 structural maintenance of chromosomes 4
SPAG8 sperm associated antigen 8
STAB1 stabilin 1
STXBP6 syntaxin binding protein 6 (amisyn)
SYMPK symplekin
TIGD6 tigger transposable element derived 6
TM4SF1 transmembrane 4 L six family member 1
TMPRSS4 transmembrane protease, serine 4
TRIM29 tripartite motif containing 29
TSPAN9 tetraspanin 9
TTLL3 tubulin tyrosine ligase-like family member 3
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF507 zinc finger protein 507
ZNF609 zinc finger protein 609
ZNF701 zinc finger protein 701

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ADM adrenomedullin
AFAP1 actin filament associated protein 1
ANP32A-IT1 ANP32A intronic transcript 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
BACE1 beta-site APP-cleaving enzyme 1
C4ORF29 chromosome 4 open reading frame 29
CD302 CD302 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPJ centromere protein J
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLEC16A C-type lectin domain family 16, member A
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COL9A2 collagen, type IX, alpha 2
CRABP1 cellular retinoic acid binding protein 1
CRBN cereblon
CTNNBIP1 catenin, beta interacting protein 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DENND4A DENN/MADD domain containing 4A
DUSP5 dual specificity phosphatase 5
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPPK1 epiplakin 1
FAM86C1 family with sequence similarity 86, member C1
FANCC Fanconi anemia, complementation group C
FBXO22 F-box protein 22
FBXW12 F-box and WD repeat domain containing 12
FKBP10 FK506 binding protein 10, 65 kDa
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCA grancalcin, EF-hand calcium binding protein
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMIP GEM interacting protein
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIRIP3 HIRA interacting protein 3
HIST1H1C histone cluster 1, H1c
HIST1H2AM histone cluster 1, H2am
HIST1H2BI histone cluster 1, H2bi
HMHA1 histocompatibility (minor) HA-1
HOOK1 hook microtubule-tethering protein 1
KAT2B K(lysine) acetyltransferase 2B
KCTD7 potassium channel tetramerization domain containing 7
KLHL21 kelch-like family member 21
LIG4 ligase IV, DNA, ATP-dependent
LINC00115 long intergenic non-protein coding RNA 115
LOC100287590 uncharacterized LOC100287590
LOC257152 uncharacterized LOC257152
LRRC61 leucine rich repeat containing 61
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPI mannose phosphate isomerase
MTA2 metastasis associated 1 family, member 2
MTMR11 myotubularin related protein 11
NDRG1 N-myc downstream regulated 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PEX26 peroxisomal biogenesis factor 26
PGPEP1 pyroglutamyl-peptidase I
PIBF1 progesterone immunomodulatory binding factor 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PODXL2 podocalyxin-like 2
PROCR protein C receptor, endothelial
PTBP2 polypyrimidine tract binding protein 2
PTDSS2 phosphatidylserine synthase 2
PTK6 protein tyrosine kinase 6
PTPRU protein tyrosine phosphatase, receptor type, U
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RANBP6 RAN binding protein 6
RASA2 RAS p21 protein activator 2
RBM42 RNA binding motif protein 42
RPAP1 RNA polymerase II associated protein 1
SETD1A SET domain containing 1A
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35F5 solute carrier family 35, member F5
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SYT17 synaptotagmin XVII
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
THBS3 thrombospondin 3
TRAIP TRAF interacting protein
TRAPPC2 trafficking protein particle complex 2
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TUBA1A tubulin, alpha 1a
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR18 WD repeat domain 18
ZCCHC8 zinc finger, CCHC domain containing 8
ZNF211 zinc finger protein 211
ZNF212 zinc finger protein 212
ZNF248 zinc finger protein 248
ZNF282 zinc finger protein 282
ZNF408 zinc finger protein 408
ZNF574 zinc finger protein 574
ZNF721 zinc finger protein 721