acetylsalicylsalicylic acid-2223 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the acetylsalicylsalicylic acid-2223 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIF1 allograft inflammatory factor 1
ALDOB aldolase B, fructose-bisphosphate
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
BCO1 beta-carotene oxygenase 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTN3A1 butyrophilin, subfamily 3, member A1
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
C8ORF44 chromosome 8 open reading frame 44
CA5B carbonic anhydrase VB, mitochondrial
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCNK cyclin K
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFHR4 complement factor H-related 4
CFLAR CASP8 and FADD-like apoptosis regulator
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
COL7A1 collagen, type VII, alpha 1
CTBP2 C-terminal binding protein 2
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DIO2 deiodinase, iodothyronine, type II
DNAI2 dynein, axonemal, intermediate chain 2
DOK4 docking protein 4
ERCC4 excision repair cross-complementation group 4
ERO1LB ERO1-like beta (S. cerevisiae)
EXOC6B exocyst complex component 6B
FABP2 fatty acid binding protein 2, intestinal
FAM131A family with sequence similarity 131, member A
FGFBP1 fibroblast growth factor binding protein 1
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GLB1L galactosidase, beta 1-like
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSK3A glycogen synthase kinase 3 alpha
HBEGF heparin-binding EGF-like growth factor
HIST1H3I histone cluster 1, H3i
IL11 interleukin 11
IL2RB interleukin 2 receptor, beta
IL6ST interleukin 6 signal transducer
INHA inhibin, alpha
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITPKA inositol-trisphosphate 3-kinase A
KLHL29 kelch-like family member 29
KLK15 kallikrein-related peptidase 15
KLK2 kallikrein-related peptidase 2
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRP12 low density lipoprotein receptor-related protein 12
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYST lysosomal trafficking regulator
MALL mal, T-cell differentiation protein-like
MBNL2 muscleblind-like splicing regulator 2
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MED18 mediator complex subunit 18
MLN motilin
MLXIP MLX interacting protein
MSL3 male-specific lethal 3 homolog (Drosophila)
MT4 metallothionein 4
MTCP1 mature T-cell proliferation 1
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NF2 neurofibromin 2 (merlin)
NT5M 5',3'-nucleotidase, mitochondrial
ONECUT2 one cut homeobox 2
PARD6B par-6 family cell polarity regulator beta
PCDH11X protocadherin 11 X-linked
PCDHA5 protocadherin alpha 5
PCNX pecanex homolog (Drosophila)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PRKCI protein kinase C, iota
RAB6A RAB6A, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RARB retinoic acid receptor, beta
REC8 REC8 meiotic recombination protein
RUFY3 RUN and FYVE domain containing 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SMIM14 small integral membrane protein 14
SORBS2 sorbin and SH3 domain containing 2
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRR2B small proline-rich protein 2B
SUGP1 SURP and G patch domain containing 1
TAOK1 TAO kinase 1
TBC1D2 TBC1 domain family, member 2
TGFB1 transforming growth factor, beta 1
TGFBR3 transforming growth factor, beta receptor III
TGM2 transglutaminase 2
TLR1 toll-like receptor 1
TRIM3 tripartite motif containing 3
TUBA3C tubulin, alpha 3c
USP48 ubiquitin specific peptidase 48
WNK1 WNK lysine deficient protein kinase 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF423 zinc finger protein 423
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOLD1 apolipoprotein L domain containing 1
ARHGAP4 Rho GTPase activating protein 4
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMC4 armadillo repeat containing 4
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BTBD2 BTB (POZ) domain containing 2
C16ORF58 chromosome 16 open reading frame 58
CAPG capping protein (actin filament), gelsolin-like
CBX8 chromobox homolog 8
CCDC132 coiled-coil domain containing 132
CDK18 cyclin-dependent kinase 18
CDK3 cyclin-dependent kinase 3
CES3 carboxylesterase 3
CLCN2 chloride channel, voltage-sensitive 2
CLCN6 chloride channel, voltage-sensitive 6
CPTP ceramide-1-phosphate transfer protein
DSCAM Down syndrome cell adhesion molecule
DTX2 deltex 2, E3 ubiquitin ligase
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ETNK2 ethanolamine kinase 2
EXD3 exonuclease 3'-5' domain containing 3
FOXC1 forkhead box C1
FRS2 fibroblast growth factor receptor substrate 2
GAMT guanidinoacetate N-methyltransferase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GPR27 G protein-coupled receptor 27
GPR87 G protein-coupled receptor 87
GRPR gastrin-releasing peptide receptor
GSTM5 glutathione S-transferase mu 5
GTPBP2 GTP binding protein 2
HIST1H2AI histone cluster 1, H2ai
HIST1H2AK histone cluster 1, H2ak
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMOX1 heme oxygenase 1
IDI2-AS1 IDI2 antisense RNA 1
IL4R interleukin 4 receptor
IRF2BP1 interferon regulatory factor 2 binding protein 1
JUNB jun B proto-oncogene
KCTD15 potassium channel tetramerization domain containing 15
KLHL25 kelch-like family member 25
LAMA3 laminin, alpha 3
LIME1 Lck interacting transmembrane adaptor 1
LRRC61 leucine rich repeat containing 61
MATK megakaryocyte-associated tyrosine kinase
MBIP MAP3K12 binding inhibitory protein 1
MRPL41 mitochondrial ribosomal protein L41
MRPL52 mitochondrial ribosomal protein L52
NEUROD4 neuronal differentiation 4
NFE2L3 nuclear factor, erythroid 2-like 3
NIPAL2 NIPA-like domain containing 2
NLRX1 NLR family member X1
NOL12 nucleolar protein 12
NPM3 nucleophosmin/nucleoplasmin 3
OSGIN1 oxidative stress induced growth inhibitor 1
OVGP1 oviductal glycoprotein 1, 120kDa
PADI1 peptidyl arginine deiminase, type I
PALM paralemmin
PCDHB13 protocadherin beta 13
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLXNA3 plexin A3
POMT2 protein-O-mannosyltransferase 2
POTEKP POTE ankyrin domain family, member K, pseudogene
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF39 ring finger protein 39
RPL10L ribosomal protein L10-like
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A2 S100 calcium binding protein A2
SEC14L5 SEC14-like 5 (S. cerevisiae)
SETD1A SET domain containing 1A
SIPA1 signal-induced proliferation-associated 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SOX3 SRY (sex determining region Y)-box 3
ST5 suppression of tumorigenicity 5
TBC1D19 TBC1 domain family, member 19
TCTN2 tectonic family member 2
TDRD1 tudor domain containing 1
TEAD3 TEA domain family member 3
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TWF2 twinfilin actin binding protein 2
TYRP1 tyrosinase-related protein 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
WNT10B wingless-type MMTV integration site family, member 10B
XKR8 XK, Kell blood group complex subunit-related family, member 8
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZNF204P zinc finger protein 204, pseudogene
ZNF442 zinc finger protein 442
ZNF74 zinc finger protein 74
ZNF787 zinc finger protein 787