acetylsalicylsalicylic acid-6778 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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193 genes differentially expressed following the acetylsalicylsalicylic acid-6778 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACAA2 acetyl-CoA acyltransferase 2
AHCYL1 adenosylhomocysteinase-like 1
BIN1 bridging integrator 1
BLZF1 basic leucine zipper nuclear factor 1
BTN3A3 butyrophilin, subfamily 3, member A3
C11ORF16 chromosome 11 open reading frame 16
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CALD1 caldesmon 1
CALML3 calmodulin-like 3
CD52 CD52 molecule
CDHR2 cadherin-related family member 2
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CLCN7 chloride channel, voltage-sensitive 7
CLDN17 claudin 17
CLEC2D C-type lectin domain family 2, member D
COL8A1 collagen, type VIII, alpha 1
CXORF21 chromosome X open reading frame 21
DCTN1 dynactin 1
DICER1 dicer 1, ribonuclease type III
DLK2 delta-like 2 homolog (Drosophila)
DLX2 distal-less homeobox 2
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DSTYK dual serine/threonine and tyrosine protein kinase
FSCN1 fascin actin-bundling protein 1
GLB1L galactosidase, beta 1-like
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GREB1 growth regulation by estrogen in breast cancer 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HIPK2 homeodomain interacting protein kinase 2
HIST1H3E histone cluster 1, H3e
HOXC5 homeobox C5
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNA14 interferon, alpha 14
IGHA1 immunoglobulin heavy constant alpha 1
IL17RC interleukin 17 receptor C
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAKMIP2 janus kinase and microtubule interacting protein 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KDM4C lysine (K)-specific demethylase 4C
KLHL22 kelch-like family member 22
LPAR4 lysophosphatidic acid receptor 4
LRP12 low density lipoprotein receptor-related protein 12
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBP2 latent transforming growth factor beta binding protein 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MCF2L MCF.2 cell line derived transforming sequence-like
METTL7A methyltransferase like 7A
MID1 midline 1
MINK1 misshapen-like kinase 1
MNDA myeloid cell nuclear differentiation antigen
MR1 major histocompatibility complex, class I-related
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCR2 natural cytotoxicity triggering receptor 2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NR2F1 nuclear receptor subfamily 2, group F, member 1
PDLIM5 PDZ and LIM domain 5
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLP1 proteolipid protein 1
PRDX2 peroxiredoxin 2
PSD3 pleckstrin and Sec7 domain containing 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD51 RAD51 recombinase
RAI2 retinoic acid induced 2
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RETN resistin
S100A2 S100 calcium binding protein A2
SCAND2P SCAN domain containing 2 pseudogene
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SLC16A4 solute carrier family 16, member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLN sarcolipin
STRA6 stimulated by retinoic acid 6
STX1A syntaxin 1A (brain)
TAGLN3 transgelin 3
TBX10 T-box 10
TBX5 T-box 5
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFA transforming growth factor, alpha
TGFBR3 transforming growth factor, beta receptor III
TJP3 tight junction protein 3
TLE4 transducin-like enhancer of split 4
TMEM8B transmembrane protein 8B
TSGA10 testis specific, 10
WFDC2 WAP four-disulfide core domain 2
ZFX zinc finger protein, X-linked
ZNF277 zinc finger protein 277
ZNF37BP zinc finger protein 37B, pseudogene
ZNF783 zinc finger family member 783
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACAD10 acyl-CoA dehydrogenase family, member 10
ACSF2 acyl-CoA synthetase family member 2
ADGRG2 adhesion G protein-coupled receptor G2
AHCYL2 adenosylhomocysteinase-like 2
AKAP12 A kinase (PRKA) anchor protein 12
B9D2 B9 protein domain 2
BAG4 BCL2-associated athanogene 4
BCORL1 BCL6 corepressor-like 1
BGLAP bone gamma-carboxyglutamate (gla) protein
C17ORF70 chromosome 17 open reading frame 70
C6ORF47 chromosome 6 open reading frame 47
CBR4 carbonyl reductase 4
CBX8 chromobox homolog 8
CCDC69 coiled-coil domain containing 69
CCNL2 cyclin L2
CDK3 cyclin-dependent kinase 3
CGA glycoprotein hormones, alpha polypeptide
CHD3 chromodomain helicase DNA binding protein 3
CNGB3 cyclic nucleotide gated channel beta 3
CTSF cathepsin F
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DENND4A DENN/MADD domain containing 4A
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ETAA1 Ewing tumor-associated antigen 1
FAM169A family with sequence similarity 169, member A
FAM188A family with sequence similarity 188, member A
FBXL6 F-box and leucine-rich repeat protein 6
FBXO22 F-box protein 22
FOSL1 FOS-like antigen 1
FSD1 fibronectin type III and SPRY domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAREM GRB2 associated, regulator of MAPK1
GATA4 GATA binding protein 4
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GID4 GID complex subunit 4
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPX2 glutathione peroxidase 2
GSTA4 glutathione S-transferase alpha 4
HDAC11 histone deacetylase 11
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
ICK intestinal cell (MAK-like) kinase
IDI2-AS1 IDI2 antisense RNA 1
INF2 inverted formin, FH2 and WH2 domain containing
KDM5C lysine (K)-specific demethylase 5C
KLHL26 kelch-like family member 26
LINC00115 long intergenic non-protein coding RNA 115
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MATK megakaryocyte-associated tyrosine kinase
MEFV Mediterranean fever
NCALD neurocalcin delta
NCAM2 neural cell adhesion molecule 2
NT5E 5'-nucleotidase, ecto (CD73)
NUP62CL nucleoporin 62kDa C-terminal like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSGIN1 oxidative stress induced growth inhibitor 1
PCDH12 protocadherin 12
PCDHB3 protocadherin beta 3
PGPEP1 pyroglutamyl-peptidase I
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLL polymerase (DNA directed), lambda
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPT2 palmitoyl-protein thioesterase 2
PRSS16 protease, serine, 16 (thymus)
R3HCC1L R3H domain and coiled-coil containing 1-like
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
SALL2 spalt-like transcription factor 2
SHPK sedoheptulokinase
SLIT2 slit homolog 2 (Drosophila)
SMR3A submaxillary gland androgen regulated protein 3A
STIM1 stromal interaction molecule 1
TICAM1 toll-like receptor adaptor molecule 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM180 transmembrane protein 180
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPCN1 two pore segment channel 1
TUBA3C tubulin, alpha 3c
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBTB25 zinc finger and BTB domain containing 25
ZDHHC11 zinc finger, DHHC-type containing 11
ZFP69B ZFP69 zinc finger protein B
ZNF205 zinc finger protein 205
ZNF282 zinc finger protein 282
ZNF668 zinc finger protein 668
ZNF787 zinc finger protein 787