aciclovir-1543 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the aciclovir-1543 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAM22 ADAM metallopeptidase domain 22
ADAM29 ADAM metallopeptidase domain 29
ADORA1 adenosine A1 receptor
AHI1 Abelson helper integration site 1
AKAP7 A kinase (PRKA) anchor protein 7
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASAP1-IT1 ASAP1 intronic transcript 1
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BAHCC1 BAH domain and coiled-coil containing 1
BAIAP2 BAI1-associated protein 2
C2ORF27A chromosome 2 open reading frame 27A
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCL27 chemokine (C-C motif) ligand 27
CDK18 cyclin-dependent kinase 18
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEP152 centrosomal protein 152kDa
COL3A1 collagen, type III, alpha 1
CRYGC crystallin, gamma C
CXORF21 chromosome X open reading frame 21
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DHRS12 dehydrogenase/reductase (SDR family) member 12
DOCK5 dedicator of cytokinesis 5
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPS8L1 EPS8-like 1
FN1 fibronectin 1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GM2A GM2 ganglioside activator
GSK3A glycogen synthase kinase 3 alpha
HIRA histone cell cycle regulator
HR hair growth associated
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IDS iduronate 2-sulfatase
IHH indian hedgehog
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IPO5 importin 5
IRS2 insulin receptor substrate 2
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KIAA0754 KIAA0754
KLF6 Kruppel-like factor 6
KLHL20 kelch-like family member 20
KLK13 kallikrein-related peptidase 13
LBP lipopolysaccharide binding protein
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPCAT4 lysophosphatidylcholine acyltransferase 4
MBNL3 muscleblind-like splicing regulator 3
MCF2L MCF.2 cell line derived transforming sequence-like
MERTK MER proto-oncogene, tyrosine kinase
MLF1 myeloid leukemia factor 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NF1 neurofibromin 1
NPR1 natriuretic peptide receptor 1
OASL 2'-5'-oligoadenylate synthetase-like
OGFR opioid growth factor receptor
PBX2 pre-B-cell leukemia homeobox 2
PCM1 pericentriolar material 1
PLA2G1B phospholipase A2, group IB (pancreas)
PLCD1 phospholipase C, delta 1
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAB6A RAB6A, member RAS oncogene family
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RBP4 retinol binding protein 4, plasma
RNF126P1 ring finger protein 126 pseudogene 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SSFA2 sperm specific antigen 2
STON1 stonin 1
STYK1 serine/threonine/tyrosine kinase 1
SYNJ2 synaptojanin 2
TM4SF1 transmembrane 4 L six family member 1
TTC28 tetratricopeptide repeat domain 28
TTC9 tetratricopeptide repeat domain 9
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
TXNL4A thioredoxin-like 4A
UNC5B unc-5 homolog B (C. elegans)
USB1 U6 snRNA biogenesis 1
VIPR1 vasoactive intestinal peptide receptor 1
VN1R1 vomeronasal 1 receptor 1
WDR76 WD repeat domain 76
ZFP64 ZFP64 zinc finger protein
ZNF324 zinc finger protein 324
ZNF358 zinc finger protein 358
ZNF362 zinc finger protein 362
ZNF551 zinc finger protein 551
ZNF8 zinc finger protein 8

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ALS2CL ALS2 C-terminal like
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOD apolipoprotein D
ASB7 ankyrin repeat and SOCS box containing 7
BAX BCL2-associated X protein
BCAP31 B-cell receptor-associated protein 31
C1ORF105 chromosome 1 open reading frame 105
C7ORF43 chromosome 7 open reading frame 43
CAMK1 calcium/calmodulin-dependent protein kinase I
CBX8 chromobox homolog 8
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CDC73 cell division cycle 73
CIDEC cell death-inducing DFFA-like effector c
CLN3 ceroid-lipofuscinosis, neuronal 3
CORO7 coronin 7
CST6 cystatin E/M
CTSD cathepsin D
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAL4 dynein, axonemal, light chain 4
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ERO1L ERO1-like (S. cerevisiae)
FAM155B family with sequence similarity 155, member B
FBXW12 F-box and WD repeat domain containing 12
FER fer (fps/fes related) tyrosine kinase
FGD1 FYVE, RhoGEF and PH domain containing 1
FOSL1 FOS-like antigen 1
FPGS folylpolyglutamate synthase
FSD1 fibronectin type III and SPRY domain containing 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GAMT guanidinoacetate N-methyltransferase
GSTA4 glutathione S-transferase alpha 4
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HINFP histone H4 transcription factor
HMOX1 heme oxygenase 1
HSPB8 heat shock 22kDa protein 8
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LIN7B lin-7 homolog B (C. elegans)
LRP2 low density lipoprotein receptor-related protein 2
MARC1 mitochondrial amidoxime reducing component 1
MMP2 matrix metallopeptidase 2
MRPL28 mitochondrial ribosomal protein L28
MRPL52 mitochondrial ribosomal protein L52
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVP major vault protein
MYO1E myosin IE
NDE1 nudE neurodevelopment protein 1
NPFFR1 neuropeptide FF receptor 1
NT5DC3 5'-nucleotidase domain containing 3
NUP153 nucleoporin 153kDa
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARP12 poly (ADP-ribose) polymerase family, member 12
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLD2 phospholipase D2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXNA3 plexin A3
PRR14L proline rich 14-like
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
RAB30 RAB30, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM42 RNA binding motif protein 42
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
SLC16A6 solute carrier family 16, member 6
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SNORA21 small nucleolar RNA, H/ACA box 21
SOWAHC sosondowah ankyrin repeat domain family member C
SRBD1 S1 RNA binding domain 1
SULT4A1 sulfotransferase family 4A, member 1
TESC tescalcin
TGFB3 transforming growth factor, beta 3
TMEM184B transmembrane protein 184B
TMEM254 transmembrane protein 254
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TSKU tsukushi, small leucine rich proteoglycan
TUBA1A tubulin, alpha 1a
UNC93B1 unc-93 homolog B1 (C. elegans)
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP19 ubiquitin specific peptidase 19
USP20 ubiquitin specific peptidase 20
VKORC1 vitamin K epoxide reductase complex, subunit 1
ZBTB22 zinc finger and BTB domain containing 22
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF211 zinc finger protein 211
ZNF480 zinc finger protein 480
ZNF74 zinc finger protein 74
ZW10 zw10 kinetochore protein