| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the aciclovir-1543 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAM29 | ADAM metallopeptidase domain 29 |
| ADORA1 | adenosine A1 receptor |
| AHI1 | Abelson helper integration site 1 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAIAP2 | BAI1-associated protein 2 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CDK18 | cyclin-dependent kinase 18 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CEP152 | centrosomal protein 152kDa |
| COL3A1 | collagen, type III, alpha 1 |
| CRYGC | crystallin, gamma C |
| CXORF21 | chromosome X open reading frame 21 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DOCK5 | dedicator of cytokinesis 5 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EPS8L1 | EPS8-like 1 |
| FN1 | fibronectin 1 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
| GM2A | GM2 ganglioside activator |
| GSK3A | glycogen synthase kinase 3 alpha |
| HIRA | histone cell cycle regulator |
| HR | hair growth associated |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 |
| IDS | iduronate 2-sulfatase |
| IHH | indian hedgehog |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IPO5 | importin 5 |
| IRS2 | insulin receptor substrate 2 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KIAA0754 | KIAA0754 |
| KLF6 | Kruppel-like factor 6 |
| KLHL20 | kelch-like family member 20 |
| KLK13 | kallikrein-related peptidase 13 |
| LBP | lipopolysaccharide binding protein |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MLF1 | myeloid leukemia factor 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NF1 | neurofibromin 1 |
| NPR1 | natriuretic peptide receptor 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OGFR | opioid growth factor receptor |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCM1 | pericentriolar material 1 |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLCD1 | phospholipase C, delta 1 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| RAB6A | RAB6A, member RAS oncogene family |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RBP4 | retinol binding protein 4, plasma |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SSFA2 | sperm specific antigen 2 |
| STON1 | stonin 1 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| SYNJ2 | synaptojanin 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TTC28 | tetratricopeptide repeat domain 28 |
| TTC9 | tetratricopeptide repeat domain 9 |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| TXNL4A | thioredoxin-like 4A |
| UNC5B | unc-5 homolog B (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VN1R1 | vomeronasal 1 receptor 1 |
| WDR76 | WD repeat domain 76 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF324 | zinc finger protein 324 |
| ZNF358 | zinc finger protein 358 |
| ZNF362 | zinc finger protein 362 |
| ZNF551 | zinc finger protein 551 |
| ZNF8 | zinc finger protein 8 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ALS2CL | ALS2 C-terminal like |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APOD | apolipoprotein D |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| BAX | BCL2-associated X protein |
| BCAP31 | B-cell receptor-associated protein 31 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CBX8 | chromobox homolog 8 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CDC73 | cell division cycle 73 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 |
| CORO7 | coronin 7 |
| CST6 | cystatin E/M |
| CTSD | cathepsin D |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FAM155B | family with sequence similarity 155, member B |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FER | fer (fps/fes related) tyrosine kinase |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FOSL1 | FOS-like antigen 1 |
| FPGS | folylpolyglutamate synthase |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GAMT | guanidinoacetate N-methyltransferase |
| GSTA4 | glutathione S-transferase alpha 4 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HINFP | histone H4 transcription factor |
| HMOX1 | heme oxygenase 1 |
| HSPB8 | heat shock 22kDa protein 8 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MMP2 | matrix metallopeptidase 2 |
| MRPL28 | mitochondrial ribosomal protein L28 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MVP | major vault protein |
| MYO1E | myosin IE |
| NDE1 | nudE neurodevelopment protein 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUP153 | nucleoporin 153kDa |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLD2 | phospholipase D2 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLXNA3 | plexin A3 |
| PRR14L | proline rich 14-like |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| RAB30 | RAB30, member RAS oncogene family |
| RAB4B | RAB4B, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBM42 | RNA binding motif protein 42 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SRBD1 | S1 RNA binding domain 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TESC | tescalcin |
| TGFB3 | transforming growth factor, beta 3 |
| TMEM184B | transmembrane protein 184B |
| TMEM254 | transmembrane protein 254 |
| TOMM40 | translocase of outer mitochondrial membrane 40 homolog (yeast) |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TUBA1A | tubulin, alpha 1a |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USP19 | ubiquitin specific peptidase 19 |
| USP20 | ubiquitin specific peptidase 20 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF211 | zinc finger protein 211 |
| ZNF480 | zinc finger protein 480 |
| ZNF74 | zinc finger protein 74 |
| ZW10 | zw10 kinetochore protein |