aciclovir-2044 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the aciclovir-2044 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ADK adenosine kinase
AQP8 aquaporin 8
ARMT1 acidic residue methyltransferase 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ART1 ADP-ribosyltransferase 1
ASPH aspartate beta-hydroxylase
ATG13 autophagy related 13
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BLZF1 basic leucine zipper nuclear factor 1
C19ORF66 chromosome 19 open reading frame 66
C4BPA complement component 4 binding protein, alpha
C4ORF29 chromosome 4 open reading frame 29
CA14 carbonic anhydrase XIV
CAST calpastatin
CCPG1 cell cycle progression 1
CCR1 chemokine (C-C motif) receptor 1
CDK10 cyclin-dependent kinase 10
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CER1 cerberus 1, DAN family BMP antagonist
CLCC1 chloride channel CLIC-like 1
CLCN3 chloride channel, voltage-sensitive 3
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CTNNBIP1 catenin, beta interacting protein 1
CTSS cathepsin S
CYB561 cytochrome b561
DBT dihydrolipoamide branched chain transacylase E2
DEDD death effector domain containing
DENND4A DENN/MADD domain containing 4A
DOK5 docking protein 5
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EID1 EP300 interacting inhibitor of differentiation 1
EIF5B eukaryotic translation initiation factor 5B
EPS8L3 EPS8-like 3
EPX eosinophil peroxidase
F3 coagulation factor III (thromboplastin, tissue factor)
FBXO5 F-box protein 5
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GML glycosylphosphatidylinositol anchored molecule like
GPR12 G protein-coupled receptor 12
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GUSBP3 glucuronidase, beta pseudogene 3
HLA-F major histocompatibility complex, class I, F
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
HUS1 HUS1 checkpoint homolog (S. pombe)
ITM2B integral membrane protein 2B
KIAA1109 KIAA1109
KRIT1 KRIT1, ankyrin repeat containing
LAMP2 lysosomal-associated membrane protein 2
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAGOHB mago-nashi homolog B (Drosophila)
MANSC1 MANSC domain containing 1
MICALL1 MICAL-like 1
MOB3B MOB kinase activator 3B
MPHOSPH9 M-phase phosphoprotein 9
MTMR2 myotubularin related protein 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NPTXR neuronal pentraxin receptor
NUP214 nucleoporin 214kDa
OLFM1 olfactomedin 1
PELP1 proline, glutamate and leucine rich protein 1
PKNOX2 PBX/knotted 1 homeobox 2
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTPRA protein tyrosine phosphatase, receptor type, A
RNASE6 ribonuclease, RNase A family, k6
RNF144A ring finger protein 144A
RNF31 ring finger protein 31
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL7 ribosomal protein L7
RPS2 ribosomal protein S2
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SCAMP1 secretory carrier membrane protein 1
SDHAF3 succinate dehydrogenase complex assembly factor 3
SEC23B Sec23 homolog B (S. cerevisiae)
SEC24D SEC24 family member D
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLMO2 slowmo homolog 2 (Drosophila)
SON SON DNA binding protein
SYMPK symplekin
TANK TRAF family member-associated NFKB activator
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TFE3 transcription factor binding to IGHM enhancer 3
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TJP2 tight junction protein 2
TRABD TraB domain containing
TRIM14 tripartite motif containing 14
TTC3 tetratricopeptide repeat domain 3
TTF2 transcription termination factor, RNA polymerase II
VAV3 vav 3 guanine nucleotide exchange factor
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
YIPF4 Yip1 domain family, member 4
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZNF518A zinc finger protein 518A
ZNF614 zinc finger protein 614

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ADRB2 adrenoceptor beta 2, surface
AEN apoptosis enhancing nuclease
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ARF5 ADP-ribosylation factor 5
ATF7IP2 activating transcription factor 7 interacting protein 2
ATG2A autophagy related 2A
AXIN1 axin 1
BATF basic leucine zipper transcription factor, ATF-like
BBC3 BCL2 binding component 3
BCL7C B-cell CLL/lymphoma 7C
C1ORF54 chromosome 1 open reading frame 54
C6ORF47 chromosome 6 open reading frame 47
CCDC88C coiled-coil domain containing 88C
CD151 CD151 molecule (Raph blood group)
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP85 centrosomal protein 85kDa
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COPS7B COP9 signalosome subunit 7B
CPNE1 copine I
CPTP ceramide-1-phosphate transfer protein
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DZANK1 double zinc ribbon and ankyrin repeat domains 1
FAM57A family with sequence similarity 57, member A
FOXK2 forkhead box K2
FUZ fuzzy planar cell polarity protein
GDAP2 ganglioside induced differentiation associated protein 2
GLB1L2 galactosidase, beta 1-like 2
GMPPB GDP-mannose pyrophosphorylase B
GSDMD gasdermin D
HIST1H1E histone cluster 1, H1e
HRAS Harvey rat sarcoma viral oncogene homolog
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGKV1D-13 immunoglobulin kappa variable 1D-13
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
INA internexin neuronal intermediate filament protein, alpha
INO80D INO80 complex subunit D
JMJD4 jumonji domain containing 4
KIFAP3 kinesin-associated protein 3
KIZ kizuna centrosomal protein
LIMD2 LIM domain containing 2
LIN7A lin-7 homolog A (C. elegans)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEF1 melanoma antigen family F1
MAN2B2 mannosidase, alpha, class 2B, member 2
MAPK3 mitogen-activated protein kinase 3
MECR mitochondrial trans-2-enoyl-CoA reductase
MICALL2 MICAL-like 2
MNS1 meiosis-specific nuclear structural 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MUC2 mucin 2, oligomeric mucus/gel-forming
MUTYH mutY homolog
NEU1 sialidase 1 (lysosomal sialidase)
NPM3 nucleophosmin/nucleoplasmin 3
NUBP2 nucleotide binding protein 2
NVL nuclear VCP-like
OSGEP O-sialoglycoprotein endopeptidase
OVGP1 oviductal glycoprotein 1, 120kDa
PARM1 prostate androgen-regulated mucin-like protein 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIGR polymeric immunoglobulin receptor
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PKN1 protein kinase N1
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
PMEL premelanosome protein
QPRT quinolinate phosphoribosyltransferase
RBM47 RNA binding motif protein 47
RNF141 ring finger protein 141
RNF220 ring finger protein 220
SCN10A sodium channel, voltage gated, type X alpha subunit
SEC31B SEC31 homolog B (S. cerevisiae)
SEPW1 selenoprotein W, 1
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNX6 sorting nexin 6
SPX spexin hormone
SRRD SRR1 domain containing
SYNGR2 synaptogyrin 2
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TEX30 testis expressed 30
TGFB3 transforming growth factor, beta 3
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM214 transmembrane protein 214
UBXN6 UBX domain protein 6
USB1 U6 snRNA biogenesis 1
WBP2 WW domain binding protein 2
WBSCR16 Williams-Beuren syndrome chromosome region 16
WDR13 WD repeat domain 13
WDR41 WD repeat domain 41
YIPF1 Yip1 domain family, member 1
ZC3H12A zinc finger CCCH-type containing 12A
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF230 zinc finger protein 230
ZNF529 zinc finger protein 529