aciclovir-4683 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the aciclovir-4683 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM11 ADAM metallopeptidase domain 11
ADGRB2 adhesion G protein-coupled receptor B2
AKAP8L A kinase (PRKA) anchor protein 8-like
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
APC adenomatous polyposis coli
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARSB arylsulfatase B
ATP11A ATPase, class VI, type 11A
B9D2 B9 protein domain 2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
C18ORF25 chromosome 18 open reading frame 25
CA5B carbonic anhydrase VB, mitochondrial
CALD1 caldesmon 1
CD58 CD58 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDK20 cyclin-dependent kinase 20
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSPP1 centrosome and spindle pole associated protein 1
CUL3 cullin 3
CXCR4 chemokine (C-X-C motif) receptor 4
DGKA diacylglycerol kinase, alpha 80kDa
DOK4 docking protein 4
E2F4 E2F transcription factor 4, p107/p130-binding
EML2 echinoderm microtubule associated protein like 2
ENG endoglin
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ERLIN1 ER lipid raft associated 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FAM105A family with sequence similarity 105, member A
FBRS fibrosin
FDPS farnesyl diphosphate synthase
FGF6 fibroblast growth factor 6
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GK glycerol kinase
GPR19 G protein-coupled receptor 19
HAO2 hydroxyacid oxidase 2 (long chain)
HSF1 heat shock transcription factor 1
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
JRK Jrk homolog (mouse)
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCTD13 potassium channel tetramerization domain containing 13
KIF1C kinesin family member 1C
KMT2A lysine (K)-specific methyltransferase 2A
LAMB4 laminin, beta 4
LINC00260 long intergenic non-protein coding RNA 260
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MKL1 megakaryoblastic leukemia (translocation) 1
MORC1 MORC family CW-type zinc finger 1
MRC2 mannose receptor, C type 2
NOL4 nucleolar protein 4
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRP1 neuropilin 1
NSUN6 NOP2/Sun domain family, member 6
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDCD2 programmed cell death 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PNPLA2 patatin-like phospholipase domain containing 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PQBP1 polyglutamine binding protein 1
PTBP3 polypyrimidine tract binding protein 3
PVR poliovirus receptor
RAB6A RAB6A, member RAS oncogene family
RERE arginine-glutamic acid dipeptide (RE) repeats
RGS5 regulator of G-protein signaling 5
RPS14 ribosomal protein S14
RTCA RNA 3'-terminal phosphate cyclase
SARM1 sterile alpha and TIR motif containing 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SCAMP1 secretory carrier membrane protein 1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SRSF5 serine/arginine-rich splicing factor 5
SS18 synovial sarcoma translocation, chromosome 18
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TCP10L t-complex 10-like
TDRD1 tudor domain containing 1
TLE4 transducin-like enhancer of split 4
TNXB tenascin XB
TP53I11 tumor protein p53 inducible protein 11
TPM1 tropomyosin 1 (alpha)
TXK TXK tyrosine kinase
VTN vitronectin
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WSB1 WD repeat and SOCS box containing 1
XDH xanthine dehydrogenase
ZBED4 zinc finger, BED-type containing 4
ZHX3 zinc fingers and homeoboxes 3
ZNF236 zinc finger protein 236

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM23 ADAM metallopeptidase domain 23
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARHGAP24 Rho GTPase activating protein 24
ARL14 ADP-ribosylation factor-like 14
ARMCX4 armadillo repeat containing, X-linked 4
ATAD5 ATPase family, AAA domain containing 5
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BDKRB1 bradykinin receptor B1
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BNC1 basonuclin 1
C11ORF63 chromosome 11 open reading frame 63
CA11 carbonic anhydrase XI
CASS4 Cas scaffolding protein family member 4
CCDC132 coiled-coil domain containing 132
CCP110 centriolar coiled coil protein 110kDa
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD82 CD82 molecule
CELA2A chymotrypsin-like elastase family, member 2A
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CNN1 calponin 1, basic, smooth muscle
CORT cortistatin
CTIF CBP80/20-dependent translation initiation factor
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DUOX2 dual oxidase 2
ECM1 extracellular matrix protein 1
EFNA3 ephrin-A3
ERCC4 excision repair cross-complementation group 4
FAM110B family with sequence similarity 110, member B
FAM13C family with sequence similarity 13, member C
FAM186A family with sequence similarity 186, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXD2 forkhead box D2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GPC3 glypican 3
GPNMB glycoprotein (transmembrane) nmb
GPR27 G protein-coupled receptor 27
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HOXC4 homeobox C4
IFT140 intraflagellar transport 140
KIFC1 kinesin family member C1
KRT20 keratin 20, type I
LAMC3 laminin, gamma 3
LGALS4 lectin, galactoside-binding, soluble, 4
LINC00472 long intergenic non-protein coding RNA 472
LOC257152 uncharacterized LOC257152
MTERF4 mitochondrial transcription termination factor 4
MYOZ3 myozenin 3
NAG18 NAG18 mRNA
NDP Norrie disease (pseudoglioma)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPIPB15 nuclear pore complex interacting protein family, member B15
NTF3 neurotrophin 3
OCA2 oculocutaneous albinism II
OLFM4 olfactomedin 4
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PADI1 peptidyl arginine deiminase, type I
PDE11A phosphodiesterase 11A
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLD2 phospholipase D2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRF1 perforin 1 (pore forming protein)
PRPH peripherin
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RIBC2 RIB43A domain with coiled-coils 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
ROM1 retinal outer segment membrane protein 1
RPH3AL rabphilin 3A-like (without C2 domains)
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCD5 stearoyl-CoA desaturase 5
SCN1B sodium channel, voltage gated, type I beta subunit
SLC17A2 solute carrier family 17, member 2
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SPTBN2 spectrin, beta, non-erythrocytic 2
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAB2 stabilin 2
STEAP4 STEAP family member 4
SYNGR3 synaptogyrin 3
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEP1 telomerase-associated protein 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM53 transmembrane protein 53
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRPC5 transient receptor potential cation channel, subfamily C, member 5
USP27X ubiquitin specific peptidase 27, X-linked
WDR76 WD repeat domain 76
ZBTB33 zinc finger and BTB domain containing 33
ZNF428 zinc finger protein 428
ZNF623 zinc finger protein 623
ZNF702P zinc finger protein 702, pseudogene
ZNF770 zinc finger protein 770