aciclovir-5278 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the aciclovir-5278 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
APOE apolipoprotein E
APOL3 apolipoprotein L, 3
ARHGAP26 Rho GTPase activating protein 26
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
C19ORF73 chromosome 19 open reading frame 73
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAV3 caveolin 3
CD1E CD1e molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD47 CD47 molecule
CD52 CD52 molecule
CD58 CD58 molecule
CD8A CD8a molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CEP112 centrosomal protein 112kDa
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLCA1 chloride channel accessory 1
CLDN11 claudin 11
CORO2B coronin, actin binding protein, 2B
CSNK1G1 casein kinase 1, gamma 1
CTNS cystinosin, lysosomal cystine transporter
DMXL2 Dmx-like 2
DOCK3 dedicator of cytokinesis 3
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EFR3B EFR3 homolog B (S. cerevisiae)
EHBP1L1 EH domain binding protein 1-like 1
EPS8L3 EPS8-like 3
EPX eosinophil peroxidase
EVI5 ecotropic viral integration site 5
FAM214B family with sequence similarity 214, member B
FCMR Fc fragment of IgM receptor
FXYD5 FXYD domain containing ion transport regulator 5
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GFER growth factor, augmenter of liver regeneration
GPR137 G protein-coupled receptor 137
GPR176 G protein-coupled receptor 176
GSTTP1 glutathione S-transferase theta pseudogene 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HPX hemopexin
IL23A interleukin 23, alpha subunit p19
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD17 potassium channel tetramerization domain containing 17
KIF26B kinesin family member 26B
KRT17 keratin 17, type I
LEPR leptin receptor
LONRF3 LON peptidase N-terminal domain and ring finger 3
MAU2 MAU2 sister chromatid cohesion factor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MR1 major histocompatibility complex, class I-related
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NF1 neurofibromin 1
OR1E1 olfactory receptor, family 1, subfamily E, member 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAPPA2 pappalysin 2
PDZRN4 PDZ domain containing ring finger 4
PER1 period circadian clock 1
PICK1 protein interacting with PRKCA 1
PLTP phospholipid transfer protein
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRM1 protamine 1
PRY PTPN13-like, Y-linked
PTAFR platelet-activating factor receptor
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
R3HDM1 R3H domain containing 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RGS10 regulator of G-protein signaling 10
RHBG Rh family, B glycoprotein (gene/pseudogene)
RPL3L ribosomal protein L3-like
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
SIX3 SIX homeobox 3
SLC39A9 solute carrier family 39, member 9
SPARCL1 SPARC-like 1 (hevin)
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STAT2 signal transducer and activator of transcription 2, 113kDa
TACC1 transforming, acidic coiled-coil containing protein 1
TBX6 T-box 6
TM4SF1 transmembrane 4 L six family member 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
UBE3A ubiquitin protein ligase E3A
UBXN1 UBX domain protein 1
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
WNT10B wingless-type MMTV integration site family, member 10B
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF137P zinc finger protein 137, pseudogene
ZNF3 zinc finger protein 3
ZNF345 zinc finger protein 345
ZNF37BP zinc finger protein 37B, pseudogene
ZNF446 zinc finger protein 446
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTL8 actin-like 8
AFF4 AF4/FMR2 family, member 4
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARMC4 armadillo repeat containing 4
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C1ORF105 chromosome 1 open reading frame 105
C1ORF159 chromosome 1 open reading frame 159
CAMK4 calcium/calmodulin-dependent protein kinase IV
CDON cell adhesion associated, oncogene regulated
CDR2L cerebellar degeneration-related protein 2-like
CES3 carboxylesterase 3
CGA glycoprotein hormones, alpha polypeptide
CHM choroideremia (Rab escort protein 1)
CHRM3 cholinergic receptor, muscarinic 3
CLCN5 chloride channel, voltage-sensitive 5
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COPZ2 coatomer protein complex, subunit zeta 2
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DMTN dematin actin binding protein
DUSP13 dual specificity phosphatase 13
FAM110B family with sequence similarity 110, member B
FAM50B family with sequence similarity 50, member B
FANCE Fanconi anemia, complementation group E
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FFAR2 free fatty acid receptor 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FOSL1 FOS-like antigen 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GAS2 growth arrest-specific 2
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRB7 growth factor receptor-bound protein 7
GSTP1 glutathione S-transferase pi 1
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H4E histone cluster 1, H4e
HMOX1 heme oxygenase 1
HOXA4 homeobox A4
HPN hepsin
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IL2 interleukin 2
ITGA8 integrin, alpha 8
KIAA0754 KIAA0754
KIAA1107 KIAA1107
KRT15 keratin 15, type I
LAMB3 laminin, beta 3
LAMP3 lysosomal-associated membrane protein 3
LARP6 La ribonucleoprotein domain family, member 6
LTBP2 latent transforming growth factor beta binding protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAST3 microtubule associated serine/threonine kinase 3
MATK megakaryocyte-associated tyrosine kinase
MTCP1 mature T-cell proliferation 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NME5 NME/NM23 family member 5
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OVOL1 ovo-like zinc finger 1
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE8B phosphodiesterase 8B
PHEX phosphate regulating endopeptidase homolog, X-linked
PITX2 paired-like homeodomain 2
PLAC1 placenta-specific 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXNA3 plexin A3
POMT2 protein-O-mannosyltransferase 2
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
R3HCC1L R3H domain and coiled-coil containing 1-like
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RFPL1S RFPL1 antisense RNA 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SLN sarcolipin
SOAT2 sterol O-acyltransferase 2
SPAG4 sperm associated antigen 4
TARP TCR gamma alternate reading frame protein
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TESK1 testis-specific kinase 1
TK1 thymidine kinase 1, soluble
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
UNC93B1 unc-93 homolog B1 (C. elegans)
USB1 U6 snRNA biogenesis 1
VIPR1 vasoactive intestinal peptide receptor 1
WDR62 WD repeat domain 62
ZBTB44 zinc finger and BTB domain containing 44
ZIC3 Zic family member 3
ZNF639 zinc finger protein 639