aciclovir-5643 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the aciclovir-5643 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
ADGRB3 adhesion G protein-coupled receptor B3
ASB1 ankyrin repeat and SOCS box containing 1
ATP10B ATPase, class V, type 10B
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BST2 bone marrow stromal cell antigen 2
C9ORF9 chromosome 9 open reading frame 9
CA4 carbonic anhydrase IV
CCNG2 cyclin G2
CD3D CD3d molecule, delta (CD3-TCR complex)
CLCN7 chloride channel, voltage-sensitive 7
CLEC11A C-type lectin domain family 11, member A
COL14A1 collagen, type XIV, alpha 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRLF2 cytokine receptor-like factor 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DTNA dystrobrevin, alpha
DTNB dystrobrevin, beta
DUX1 double homeobox 1
DZIP3 DAZ interacting zinc finger protein 3
EFNB3 ephrin-B3
EGFL7 EGF-like-domain, multiple 7
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EVA1B eva-1 homolog B (C. elegans)
F13A1 coagulation factor XIII, A1 polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FGF13 fibroblast growth factor 13
FLJ11710 uncharacterized protein FLJ11710
FLRT2 fibronectin leucine rich transmembrane protein 2
FSCN3 fascin actin-bundling protein 3, testicular
GAST gastrin
GLB1L galactosidase, beta 1-like
GNAS GNAS complex locus
HOXA6 homeobox A6
HOXD1 homeobox D1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT27 intraflagellar transport 27
IL17RC interleukin 17 receptor C
JRK Jrk homolog (mouse)
KCTD12 potassium channel tetramerization domain containing 12
KLHL24 kelch-like family member 24
KRT17 keratin 17, type I
KSR1 kinase suppressor of ras 1
LAMB4 laminin, beta 4
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MAPK14 mitogen-activated protein kinase 14
MCF2L MCF.2 cell line derived transforming sequence-like
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MNDA myeloid cell nuclear differentiation antigen
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MXD3 MAX dimerization protein 3
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
N4BP2L1 NEDD4 binding protein 2-like 1
NEK9 NIMA-related kinase 9
NIPAL3 NIPA-like domain containing 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PARVA parvin, alpha
PBX2 pre-B-cell leukemia homeobox 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE10A phosphodiesterase 10A
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PLD1 phospholipase D1, phosphatidylcholine-specific
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PTGER3 prostaglandin E receptor 3 (subtype EP3)
R3HDM1 R3H domain containing 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
REEP2 receptor accessory protein 2
RFPL1S RFPL1 antisense RNA 1
RLN1 relaxin 1
RPS28 ribosomal protein S28
RXRB retinoid X receptor, beta
SC5D sterol-C5-desaturase
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SPON1 spondin 1, extracellular matrix protein
SPRR2B small proline-rich protein 2B
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SRSF5 serine/arginine-rich splicing factor 5
SSX1 synovial sarcoma, X breakpoint 1
TAPBP TAP binding protein (tapasin)
TEF thyrotrophic embryonic factor
TFEB transcription factor EB
TM4SF4 transmembrane 4 L six family member 4
TM4SF5 transmembrane 4 L six family member 5
TSC22D2 TSC22 domain family, member 2
TSPAN9 tetraspanin 9
TXNIP thioredoxin interacting protein
VASH2 vasohibin 2
VIM vimentin
XAF1 XIAP associated factor 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YPEL1 yippee-like 1 (Drosophila)
ZNF440 zinc finger protein 440
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ADCK4 aarF domain containing kinase 4
AEN apoptosis enhancing nuclease
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AMT aminomethyltransferase
ANXA2P3 annexin A2 pseudogene 3
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BHLHE41 basic helix-loop-helix family, member e41
C11ORF63 chromosome 11 open reading frame 63
C7ORF43 chromosome 7 open reading frame 43
CABP2 calcium binding protein 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC71 coiled-coil domain containing 71
CEP72 centrosomal protein 72kDa
CFAP45 cilia and flagella associated protein 45
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLIC2 chloride intracellular channel 2
CPED1 cadherin-like and PC-esterase domain containing 1
CTPS1 CTP synthase 1
DBF4B DBF4 zinc finger B
DDIT3 DNA-damage-inducible transcript 3
DENND5B DENN/MADD domain containing 5B
DVL1 dishevelled segment polarity protein 1
EPHA2 EPH receptor A2
EPX eosinophil peroxidase
F9 coagulation factor IX
FAM184A family with sequence similarity 184, member A
FAM189A2 family with sequence similarity 189, member A2
FLJ22184
FOSL1 FOS-like antigen 1
FOXN2 forkhead box N2
FRMD1 FERM domain containing 1
GFI1 growth factor independent 1 transcription repressor
GJA9 gap junction protein, alpha 9, 59kDa
GMIP GEM interacting protein
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
HCFC2 host cell factor C2
HMOX1 heme oxygenase 1
HPN hepsin
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HYI hydroxypyruvate isomerase (putative)
IBSP integrin-binding sialoprotein
IGSF6 immunoglobulin superfamily, member 6
IL2RB interleukin 2 receptor, beta
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM8 lysine (K)-specific demethylase 8
KIAA1456 KIAA1456
KRT15 keratin 15, type I
LINC00597 long intergenic non-protein coding RNA 597
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOXL3 lysyl oxidase-like 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MSI1 musashi RNA-binding protein 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NOP2 NOP2 nucleolar protein
OCA2 oculocutaneous albinism II
ONECUT1 one cut homeobox 1
OVOL1 ovo-like zinc finger 1
OXCT2 3-oxoacid CoA transferase 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
POM121L2 POM121 transmembrane nucleoporin-like 2
PPT2 palmitoyl-protein thioesterase 2
PRB3 proline-rich protein BstNI subfamily 3
PROCR protein C receptor, endothelial
PRSS22 protease, serine, 22
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNF43 ring finger protein 43
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPL10L ribosomal protein L10-like
SAG S-antigen; retina and pineal gland (arrestin)
SENP7 SUMO1/sentrin specific peptidase 7
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC12A8 solute carrier family 12, member 8
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNTA1 syntrophin, alpha 1
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STEAP1 six transmembrane epithelial antigen of the prostate 1
TGFBR3 transforming growth factor, beta receptor III
TMCC2 transmembrane and coiled-coil domain family 2
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VIPR1 vasoactive intestinal peptide receptor 1
YY2 YY2 transcription factor
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF204P zinc finger protein 204, pseudogene
ZNF205 zinc finger protein 205
ZNF350 zinc finger protein 350
ZNF711 zinc finger protein 711
ZNF787 zinc finger protein 787