acne Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors. (Experimental Factor Ontology, EFO_0003894)
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Genes

90 genes co-occuring with the disease acne in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SHBG sex hormone-binding globulin 1.61128
AARS alanyl-tRNA synthetase 1.29877
OVOL1 ovo-like zinc finger 1 1.09965
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 1.08705
DEFB4A defensin, beta 4A 1.06564
NCSTN nicastrin 1.01934
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.01005
SESN3 sestrin 3 0.978426
PSENEN presenilin enhancer gamma secretase subunit 0.947435
SMNDC1 survival motor neuron domain containing 1 0.876148
DGAT1 diacylglycerol O-acyltransferase 1 0.86714
TLR2 toll-like receptor 2 0.86018
IGF1 insulin-like growth factor 1 (somatomedin C) 0.852811
ASIP agouti signaling protein 0.834378
NPS neuropeptide S 0.822897
FOXO1 forkhead box O1 0.813462
CASS4 Cas scaffolding protein family member 4 0.777795
AR androgen receptor 0.768801
RNASE7 ribonuclease, RNase A family, 7 0.752492
APH1A APH1A gamma secretase subunit 0.72612
ILVBL ilvB (bacterial acetolactate synthase)-like 0.694301
KRT75 keratin 75, type II 0.663578
IL1A interleukin 1, alpha 0.648928
SOD2 superoxide dismutase 2, mitochondrial 0.644586
TRIP10 thyroid hormone receptor interactor 10 0.644192
PLIN1 perilipin 1 0.632384
FGFR2 fibroblast growth factor receptor 2 0.583552
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 0.567997
IL17RC interleukin 17 receptor C 0.56722
MMP1 matrix metallopeptidase 1 0.54393
CCNE1 cyclin E1 0.538118
POLB polymerase (DNA directed), beta 0.529222
FLNA filamin A, alpha 0.529222
NLRC4 NLR family, CARD domain containing 4 0.519575
PPARA peroxisome proliferator-activated receptor alpha 0.518805
MEFV Mediterranean fever 0.506123
INS insulin 0.499614
ZMYND10 zinc finger, MYND-type containing 10 0.496557
GGN gametogenetin 0.495411
FLAD1 flavin adenine dinucleotide synthetase 1 0.479047
RD3 retinal degeneration 3 0.475255
CXCL8 chemokine (C-X-C motif) ligand 8 0.455601
MMP13 matrix metallopeptidase 13 0.454847
CAT catalase 0.444676
KLK5 kallikrein-related peptidase 5 0.43941
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.420266
RORC RAR-related orphan receptor C 0.405305
AIM2 absent in melanoma 2 0.404931
NLRP3 NLR family, pyrin domain containing 3 0.403811
TIMP2 TIMP metallopeptidase inhibitor 2 0.381852
TAC1 tachykinin, precursor 1 0.373698
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.355972
FES FES proto-oncogene, tyrosine kinase 0.347511
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.341272
PSEN1 presenilin 1 0.336144
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.335412
TNF tumor necrosis factor 0.333583
DEFB1 defensin, beta 1 0.333218
SPINK5 serine peptidase inhibitor, Kazal type 5 0.318272
MVK mevalonate kinase 0.307757
PPP4C protein phosphatase 4, catalytic subunit 0.306672
TLR6 toll-like receptor 6 0.296211
MMP9 matrix metallopeptidase 9 0.289744
CD2 CD2 molecule 0.283655
S100A7 S100 calcium binding protein A7 0.281153
XPO1 exportin 1 0.261952
IL1B interleukin 1, beta 0.238403
MMP2 matrix metallopeptidase 2 0.23492
POMC proopiomelanocortin 0.233878
APOA1 apolipoprotein A-I 0.230409
MRAP melanocortin 2 receptor accessory protein 0.227297
IL4R interleukin 4 receptor 0.213621
ADSL adenylosuccinate lyase 0.211597
WAPAL wings apart-like homolog (Drosophila) 0.210253
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.208914
PRL prolactin 0.193285
SOS1 son of sevenless homolog 1 (Drosophila) 0.193285
GPX5 glutathione peroxidase 5 0.189244
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.188938
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.187719
GPX4 glutathione peroxidase 4 0.18651
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.185016
LTF lactotransferrin 0.182666
TLR1 toll-like receptor 1 0.17896
SREBF1 sterol regulatory element binding transcription factor 1 0.176757
GPX1 glutathione peroxidase 1 0.175146
CD209 CD209 molecule 0.173571
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 0.163729
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.163111
ANPEP alanyl (membrane) aminopeptidase 0.161139