acne Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors. (Experimental Factor Ontology, EFO_0003894)
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Genes

37 genes co-occuring with the biological term acne in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
AR androgen receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
DEFB4A defensin, beta 4A
DPP4 dipeptidyl-peptidase 4
F2R coagulation factor II (thrombin) receptor
FLG filaggrin
FOXO1 forkhead box O1
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL22 interleukin 22
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
INS insulin
LCN2 lipocalin 2
MME membrane metallo-endopeptidase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NCSTN nicastrin
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
PPARG peroxisome proliferator-activated receptor gamma
PSEN1 presenilin 1
PSENEN presenilin enhancer gamma secretase subunit
RARA retinoic acid receptor, alpha
S100A7 S100 calcium binding protein A7
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B