acne Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors. (Experimental Factor Ontology, EFO_0003894)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0001061
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Genes

33 genes associated with the acne phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
AGA aspartylglucosaminidase
AIP aryl hydrocarbon receptor interacting protein
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
C4A complement component 4A (Rodgers blood group)
COMT catechol-O-methyltransferase
ECM1 extracellular matrix protein 1
FGFR2 fibroblast growth factor receptor 2
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit
GP1BB glycoprotein Ib (platelet), beta polypeptide
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HIRA histone cell cycle regulator
HLA-B major histocompatibility complex, class I, B
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IL10 interleukin 10
IL12RB2 interleukin 12 receptor, beta 2
IL23R interleukin 23 receptor
LHCGR luteinizing hormone/choriogonadotropin receptor
LPIN2 lipin 2
MEFV Mediterranean fever
MEIS2 Meis homeobox 2
NOD2 nucleotide-binding oligomerization domain containing 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
SH3PXD2B SH3 and PX domains 2B
SLCO2A1 solute carrier organic anion transporter family, member 2A1
STAT4 signal transducer and activator of transcription 4
TBX1 T-box 1
TLR4 toll-like receptor 4
UFD1L ubiquitin fusion degradation 1 like (yeast)
WNT4 wingless-type MMTV integration site family, member 4