| Dataset | GO Molecular Function Annotations 2025 |
| Category | structural or functional annotations |
| Type | molecular function |
| Description | Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate. (Gene Ontology, GO_0003994) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0003994 |
| Similar Terms | |
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3 genes performing the aconitate hydratase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.
