| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the aconitine-1784 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| APH1B | APH1B gamma secretase subunit |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATG2A | autophagy related 2A |
| ATXN2 | ataxin 2 |
| C17ORF75 | chromosome 17 open reading frame 75 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
| CCKAR | cholecystokinin A receptor |
| CDC14A | cell division cycle 14A |
| CDK12 | cyclin-dependent kinase 12 |
| CHN2 | chimerin 2 |
| CTIF | CBP80/20-dependent translation initiation factor |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DMBT1 | deleted in malignant brain tumors 1 |
| DOK2 | docking protein 2, 56kDa |
| DST | dystonin |
| EGFR | epidermal growth factor receptor |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FGL1 | fibrinogen-like 1 |
| FMOD | fibromodulin |
| FRMD1 | FERM domain containing 1 |
| FZD4 | frizzled class receptor 4 |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GSK3A | glycogen synthase kinase 3 alpha |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| IQCK | IQ motif containing K |
| KHSRP | KH-type splicing regulatory protein |
| LAD1 | ladinin 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAGED2 | melanoma antigen family D2 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MOB3B | MOB kinase activator 3B |
| MR1 | major histocompatibility complex, class I-related |
| MTAP | methylthioadenosine phosphorylase |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MXD4 | MAX dimerization protein 4 |
| MYRF | myelin regulatory factor |
| NDRG2 | NDRG family member 2 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NPPA | natriuretic peptide A |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NTF3 | neurotrophin 3 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OGG1 | 8-oxoguanine DNA glycosylase |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| OPRK1 | opioid receptor, kappa 1 |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| PADI1 | peptidyl arginine deiminase, type I |
| PADI2 | peptidyl arginine deiminase, type II |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PISD | phosphatidylserine decarboxylase |
| PITPNA | phosphatidylinositol transfer protein, alpha |
| PKN1 | protein kinase N1 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| POMT1 | protein-O-mannosyltransferase 1 |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTK2 | protein tyrosine kinase 2 |
| PTMA | prothymosin, alpha |
| RAD51D | RAD51 paralog D |
| REC8 | REC8 meiotic recombination protein |
| RGS12 | regulator of G-protein signaling 12 |
| RGSL1 | regulator of G-protein signaling like 1 |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAS2R1 | taste receptor, type 2, member 1 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM159 | transmembrane protein 159 |
| TMEM70 | transmembrane protein 70 |
| TNS1 | tensin 1 |
| TOX4 | TOX high mobility group box family member 4 |
| TPD52L1 | tumor protein D52-like 1 |
| TRAIP | TRAF interacting protein |
| TRIM10 | tripartite motif containing 10 |
| TUBA4B | tubulin, alpha 4b |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZFAND6 | zinc finger, AN1-type domain 6 |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF419 | zinc finger protein 419 |
| ZNF473 | zinc finger protein 473 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD11 | ankyrin repeat domain 11 |
| ANKRD46 | ankyrin repeat domain 46 |
| ANXA2P2 | annexin A2 pseudogene 2 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APOBR | apolipoprotein B receptor |
| ATG4A | autophagy related 4A, cysteine peptidase |
| AUP1 | ancient ubiquitous protein 1 |
| AZI2 | 5-azacytidine induced 2 |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C16ORF62 | chromosome 16 open reading frame 62 |
| CCDC25 | coiled-coil domain containing 25 |
| CCDC86 | coiled-coil domain containing 86 |
| CCNT1 | cyclin T1 |
| CD9 | CD9 molecule |
| CEP85 | centrosomal protein 85kDa |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| COQ2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase |
| COQ6 | coenzyme Q6 monooxygenase |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CS | citrate synthase |
| CTSG | cathepsin G |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM222B | family with sequence similarity 222, member B |
| FAM46A | family with sequence similarity 46, member A |
| GBAS | glioblastoma amplified sequence |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GTF2I | general transcription factor IIi |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HEATR3 | HEAT repeat containing 3 |
| IMPACT | impact RWD domain protein |
| IPCEF1 | interaction protein for cytohesin exchange factors 1 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIAA0894 | KIAA0894 protein |
| KIF15 | kinesin family member 15 |
| KIF4A | kinesin family member 4A |
| KIFC1 | kinesin family member C1 |
| KLHL12 | kelch-like family member 12 |
| LACTB2 | lactamase, beta 2 |
| LBR | lamin B receptor |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MEIS2 | Meis homeobox 2 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MID1IP1 | MID1 interacting protein 1 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MRPS34 | mitochondrial ribosomal protein S34 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| NADSYN1 | NAD synthetase 1 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NRBP1 | nuclear receptor binding protein 1 |
| NUCB2 | nucleobindin 2 |
| NUP43 | nucleoporin 43kDa |
| NXF3 | nuclear RNA export factor 3 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PEPD | peptidase D |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PMPCB | peptidase (mitochondrial processing) beta |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform |
| PRMT3 | protein arginine methyltransferase 3 |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPL34 | ribosomal protein L34 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC35E3 | solute carrier family 35, member E3 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| STAR | steroidogenic acute regulatory protein |
| SYT13 | synaptotagmin XIII |
| TCTN2 | tectonic family member 2 |
| TMEM33 | transmembrane protein 33 |
| TMEM38B | transmembrane protein 38B |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TSPYL2 | TSPY-like 2 |
| TTBK2 | tau tubulin kinase 2 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBQLN2 | ubiquilin 2 |
| UNC50 | unc-50 homolog (C. elegans) |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| WDR13 | WD repeat domain 13 |
| WDR37 | WD repeat domain 37 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZNF271P | zinc finger protein 271, pseudogene |
| ZNF443 | zinc finger protein 443 |
