| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the aconitine-7149 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AASS | aminoadipate-semialdehyde synthase |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CCNG2 | cyclin G2 |
| CENPQ | centromere protein Q |
| CHD7 | chromodomain helicase DNA binding protein 7 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| E2F1 | E2F transcription factor 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EEA1 | early endosome antigen 1 |
| EFNA1 | ephrin-A1 |
| EIF4ENIF1 | eukaryotic translation initiation factor 4E nuclear import factor 1 |
| EMP1 | epithelial membrane protein 1 |
| ETV1 | ets variant 1 |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FGF13 | fibroblast growth factor 13 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP5 | FK506 binding protein 5 |
| FOXO1 | forkhead box O1 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GK | glycerol kinase |
| GPATCH2L | G patch domain containing 2-like |
| H1F0 | H1 histone family, member 0 |
| H2AFX | H2A histone family, member X |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HIST1H1D | histone cluster 1, H1d |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| KIFC1 | kinesin family member C1 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LDB1 | LIM domain binding 1 |
| LMNB1 | lamin B1 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LRRC61 | leucine rich repeat containing 61 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MARS | methionyl-tRNA synthetase |
| MATN3 | matrilin 3 |
| MAX | MYC associated factor X |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MCL1 | myeloid cell leukemia 1 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MUC3B | mucin 3B, cell surface associated |
| MVK | mevalonate kinase |
| NF1 | neurofibromin 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDAP1 | PDGFA associated protein 1 |
| PEX5 | peroxisomal biogenesis factor 5 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCD1 | phospholipase C, delta 1 |
| PPP2R4 | protein phosphatase 2A activator, regulatory subunit 4 |
| RAB31 | RAB31, member RAS oncogene family |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RANGAP1 | Ran GTPase activating protein 1 |
| RFK | riboflavin kinase |
| RNF170 | ring finger protein 170 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| RUNX3 | runt-related transcription factor 3 |
| S100A11 | S100 calcium binding protein A11 |
| S100A3 | S100 calcium binding protein A3 |
| SCARB2 | scavenger receptor class B, member 2 |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SHROOM2 | shroom family member 2 |
| SKIL | SKI-like proto-oncogene |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SOCS6 | suppressor of cytokine signaling 6 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| STK16 | serine/threonine kinase 16 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TRAK1 | trafficking protein, kinesin binding 1 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VEGFA | vascular endothelial growth factor A |
| WT1 | Wilms tumor 1 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF174 | zinc finger protein 174 |
| ZNF345 | zinc finger protein 345 |
| Symbol | Name |
|---|---|
| ADAMTSL3 | ADAMTS-like 3 |
| ALPK1 | alpha-kinase 1 |
| ANAPC2 | anaphase promoting complex subunit 2 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ATG4A | autophagy related 4A, cysteine peptidase |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BBS1 | Bardet-Biedl syndrome 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTBD2 | BTB (POZ) domain containing 2 |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CAPN5 | calpain 5 |
| CARD8 | caspase recruitment domain family, member 8 |
| CFAP44 | cilia and flagella associated protein 44 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNTNAP1 | contactin associated protein 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| ERF | Ets2 repressor factor |
| ESRP2 | epithelial splicing regulatory protein 2 |
| ETNK2 | ethanolamine kinase 2 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FANCF | Fanconi anemia, complementation group F |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FIG4 | FIG4 phosphoinositide 5-phosphatase |
| FLCN | folliculin |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GPR3 | G protein-coupled receptor 3 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOMER2 | homer scaffolding protein 2 |
| HOOK2 | hook microtubule-tethering protein 2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IREB2 | iron-responsive element binding protein 2 |
| KIAA0232 | KIAA0232 |
| KIAA0513 | KIAA0513 |
| KIAA0894 | KIAA0894 protein |
| KIAA0895 | KIAA0895 |
| KLK6 | kallikrein-related peptidase 6 |
| KRT4 | keratin 4, type II |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LOC100127972 | uncharacterized LOC100127972 |
| LOC730101 | uncharacterized LOC730101 |
| MAN2B2 | mannosidase, alpha, class 2B, member 2 |
| MED9 | mediator complex subunit 9 |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MNS1 | meiosis-specific nuclear structural 1 |
| MOCOS | molybdenum cofactor sulfurase |
| MON1B | MON1 secretory trafficking family member B |
| NDRG4 | NDRG family member 4 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| NME5 | NME/NM23 family member 5 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLD2 | phospholipase D2 |
| POLH | polymerase (DNA directed), eta |
| POLL | polymerase (DNA directed), lambda |
| POLM | polymerase (DNA directed), mu |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTK6 | protein tyrosine kinase 6 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RAB3A | RAB3A, member RAS oncogene family |
| RBL1 | retinoblastoma-like 1 |
| RBM6 | RNA binding motif protein 6 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SETD1B | SET domain containing 1B |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SMA4 | glucuronidase, beta pseudogene |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) |
| TEX40 | testis expressed 40 |
| TMEM121 | transmembrane protein 121 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TSKU | tsukushi, small leucine rich proteoglycan |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZFP36 | ZFP36 ring finger protein |
| ZNF34 | zinc finger protein 34 |
| ZNF350 | zinc finger protein 350 |
| ZNF408 | zinc finger protein 408 |
| ZNF770 | zinc finger protein 770 |
