actin filament Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. (Gene Ontology, GO_0005884)
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50 proteins localized to the actin filament cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ACTC1 actin, alpha, cardiac muscle 1 0.663342
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.663342
MYO3A myosin IIIA 0.663342
MYO9B myosin IXB 0.663342
MYO1A myosin IA 0.663342
CORO1A coronin, actin binding protein, 1A 0.663342
DMTN dematin actin binding protein 0.663342
CD2AP CD2-associated protein 0.663342
ACTA1 actin, alpha 1, skeletal muscle 0.663342
ARHGAP6 Rho GTPase activating protein 6 0.663342
MYO6 myosin VI 0.663342
MARK2 MAP/microtubule affinity-regulating kinase 2 0.663342
AMOT angiomotin 0.663342
MYO1C myosin IC 0.663342
CORO1B coronin, actin binding protein, 1B 0.237908
PALLD palladin, cytoskeletal associated protein 0.237908
RHOQ ras homolog family member Q 0.237908
APC2 adenomatosis polyposis coli 2 0.237908
GAS2 growth arrest-specific 2 0.237908
IQGAP1 IQ motif containing GTPase activating protein 1 0.237908
ESPN espin 0.237908
EZR ezrin 0.237908
DPYSL3 dihydropyrimidinase-like 3 0.237908
ACTN2 actinin, alpha 2 0.237908
MYO1B myosin IB 0.237908
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.098109
LRRC16A leucine rich repeat containing 16A 0.098109
RCSD1 RCSD domain containing 1 0.098109
FLNA filamin A, alpha 0.03318
FERMT2 fermitin family member 2 0.03318
AIF1 allograft inflammatory factor 1 0.03318
SH2B2 SH2B adaptor protein 2 0.03318
WIPF1 WAS/WASL interacting protein family, member 1 0.03318
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 0.03318
SHROOM2 shroom family member 2 0.03318
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 0.03318
FMN1 formin 1 0.03318
BIN3 bridging integrator 3 0.03318
TPM1 tropomyosin 1 (alpha) 0.03318
TPM4 tropomyosin 4 0.03318
FERMT1 fermitin family member 1 0.03318
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 0.03318
DFNB31 deafness, autosomal recessive 31 0.03318
ANKRD26 ankyrin repeat domain 26 0.03318
MYO1F myosin IF 0.03318
COBL cordon-bleu WH2 repeat protein 0.03318
ACTG1 actin gamma 1 0.03318
FKBP15 FK506 binding protein 15, 133kDa 0.03318
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 0.03318
GAS7 growth arrest-specific 7 0.03318