activators Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

207 genes co-occuring with the biological term activators in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAM17 ADAM metallopeptidase domain 17
ADRB2 adrenoceptor beta 2, surface
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT2 angiopoietin 2
APOA5 apolipoprotein A-V
AQP3 aquaporin 3 (Gill blood group)
AR androgen receptor
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATM ATM serine/threonine kinase
AURKA aurora kinase A
BAX BCL2-associated X protein
BCL2L1 BCL2-like 1
C3 complement component 3
CA5A carbonic anhydrase VA, mitochondrial
CA5B carbonic anhydrase VB, mitochondrial
CAPN10 calpain 10
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CD36 CD36 molecule (thrombospondin receptor)
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK2 checkpoint kinase 2
CLOCK clock circadian regulator
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COL1A1 collagen, type I, alpha 1
CREB1 cAMP responsive element binding protein 1
CREM cAMP responsive element modulator
CXCL8 chemokine (C-X-C motif) ligand 8
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DVL3 dishevelled segment polarity protein 3
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNLL1 dynein, light chain, LC8-type 1
EGFR epidermal growth factor receptor
ELAVL1 ELAV like RNA binding protein 1
ELL2 elongation factor, RNA polymerase II, 2
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F10 coagulation factor X
F2RL1 coagulation factor II (thrombin) receptor-like 1
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAS Fas cell surface death receptor
FGA fibrinogen alpha chain
FGF2 fibroblast growth factor 2 (basic)
FGF21 fibroblast growth factor 21
FGFR1 fibroblast growth factor receptor 1
FHL5 four and a half LIM domains 5
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FIZ1 FLT3-interacting zinc finger 1
FLT1 fms-related tyrosine kinase 1
FNDC5 fibronectin type III domain containing 5
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXM1 forkhead box M1
FOXO3 forkhead box O3
GFI1B growth factor independent 1B transcription repressor
GH1 growth hormone 1
GPR119 G protein-coupled receptor 119
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HABP2 hyaluronan binding protein 2
HDL3 Huntington-like neurodegenerative disorder 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HNF4A hepatocyte nuclear factor 4, alpha
HRAS Harvey rat sarcoma viral oncogene homolog
HRK harakiri, BCL2 interacting protein
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
IFI16 interferon, gamma-inducible protein 16
IFNG interferon, gamma
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL1B interleukin 1, beta
IL22 interleukin 22
IL6 interleukin 6
ITGAV integrin, alpha V
JUN jun proto-oncogene
KCNIP3 Kv channel interacting protein 3, calsenilin
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KEAP1 kelch-like ECH-associated protein 1
KLK3 kallikrein-related peptidase 3
LIF leukemia inhibitory factor
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MCL1 myeloid cell leukemia 1
MCOLN2 mucolipin 2
MEF2A myocyte enhancer factor 2A
MEF2D myocyte enhancer factor 2D
MET MET proto-oncogene, receptor tyrosine kinase
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MOGS mannosyl-oligosaccharide glucosidase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCAM1 neural cell adhesion molecule 1
NCKIPSD NCK interacting protein with SH3 domain
NCOA2 nuclear receptor coactivator 2
NDFIP1 Nedd4 family interacting protein 1
NDFIP2 Nedd4 family interacting protein 2
NFE2 nuclear factor, erythroid 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP3 NLR family, pyrin domain containing 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NOSTRIN nitric oxide synthase trafficking
NOX1 NADPH oxidase 1
NOX3 NADPH oxidase 3
NOX4 NADPH oxidase 4
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR5A1 nuclear receptor subfamily 5, group A, member 1
OXSR1 oxidative stress responsive 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKM pyruvate kinase, muscle
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLG plasminogen
PLK4 polo-like kinase 4
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCD protein kinase C, delta
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
PRKG1 protein kinase, cGMP-dependent, type I
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PURA purine-rich element binding protein A
PURB purine-rich element binding protein B
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RETN resistin
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RORA RAR-related orphan receptor A
RYR1 ryanodine receptor 1 (skeletal)
SEPP1 selenoprotein P, plasma, 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPB surfactant protein B
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOAT1 sterol O-acyltransferase 1
SOAT2 sterol O-acyltransferase 2
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPP1 secreted phosphoprotein 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK11 serine/threonine kinase 11
STK39 serine threonine kinase 39
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3
TBXA2R thromboxane A2 receptor
TFEC transcription factor EC
TIMP1 TIMP metallopeptidase inhibitor 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TRAF3IP2 TRAF3 interacting protein 2
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
UCN urocortin
UCN2 urocortin 2
UCN3 urocortin 3
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
USP22 ubiquitin specific peptidase 22
UTRN utrophin
VEGFA vascular endothelial growth factor A
WNK1 WNK lysine deficient protein kinase 1
ZBTB7B zinc finger and BTB domain containing 7B