Hepatic failure refers to the inability of the liver to perform its normal synthetic and metabolic functions, which can result in coagulopathy and alteration in the mental status of a previously healthy individual. Hepatic failure is defined as acute if there is onset of encephalopathy within 8 weeks of the onset of symptoms in a patient with a previously healthy liver. (Human Phenotype Ontology, HP_0006554)
14 genes associated with the acute hepatic failure phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.
