A leukemia that occurs when a hematopoietic stem cell undergoes malignant transformation into a primitive, undifferentiated cell with abnormal longevity. These lymphocytes (acute lymphocytic leukemia [ALL]) or myeloid cells (acute myelocytic leukemia [AML]) proliferate abnormally, replacing normal marrow tissue and hematopoietic cells and inducing anemia, thrombocytopenia, and granulocytopenia. (Human Disease Ontology, DOID_12603)
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Genes
1 genes associated with the disease acute leukemia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
