adamts13 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description ADAM metallopeptidase with thrombospondin type 1 motif, 13|This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] (NCBI Entrez Gene Database, 11093)
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Genes

18 genes co-occuring with the biological term adamts13 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
CFH complement factor H
F8 coagulation factor VIII, procoagulant component
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP6 glycoprotein VI (platelet)
HBA1 hemoglobin, alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IL1B interleukin 1, beta
MRC1 mannose receptor, C type 1
PLG plasminogen
PPIB peptidylprolyl isomerase B (cyclophilin B)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
THBS1 thrombospondin 1
VWA2 von Willebrand factor A domain containing 2
VWF von Willebrand factor