addiction Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Disorders related to substance abuse, the side effects of a medication, or toxin exposure. (Experimental Factor Ontology, EFO_0003890)
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Genes

63 genes co-occuring with the biological term addiction in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADGRL3 adhesion G protein-coupled receptor L3
ADRBK2 adrenergic, beta, receptor kinase 2
ANKK1 ankyrin repeat and kinase domain containing 1
AR androgen receptor
ATF2 activating transcription factor 2
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BRAF B-Raf proto-oncogene, serine/threonine kinase
CARTPT CART prepropeptide
CDK5 cyclin-dependent kinase 5
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHRM2 cholinergic receptor, muscarinic 2
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CNR1 cannabinoid receptor 1 (brain)
CNTNAP2 contactin associated protein-like 2
COMT catechol-O-methyltransferase
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CRH corticotropin releasing hormone
CTNNA2 catenin (cadherin-associated protein), alpha 2
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
EGFR epidermal growth factor receptor
FADD Fas (TNFRSF6)-associated via death domain
FKBP5 FK506 binding protein 5
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GDNF glial cell derived neurotrophic factor
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
HOMER1 homer scaffolding protein 1
HRH3 histamine receptor H3
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MET MET proto-oncogene, receptor tyrosine kinase
MIR181A1 microRNA 181a-1
MITF microphthalmia-associated transcription factor
MST1R macrophage stimulating 1 receptor
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCK2 NCK adaptor protein 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRD1 nardilysin (N-arginine dibasic convertase)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
PDYN prodynorphin
PER2 period circadian clock 2
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKCE protein kinase C, epsilon
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
TBK1 TANK-binding kinase 1
TFCP2 transcription factor CP2
TPH1 tryptophan hydroxylase 1
TUBA4A tubulin, alpha 4a
WLS wntless Wnt ligand secretion mediator
ZBP1 Z-DNA binding protein 1