adenosine deaminase deficiency Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A severe combined immunodeficiency that is caused by a defective enzyme, adenosine deaminase (ADA), necessary for the breakdown of purines. Lack of ADA causes accumulation of dATP. (Human Disease Ontology, DOID_5810)
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37 genes co-occuring with the disease adenosine deaminase deficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ADA adenosine deaminase 2.78064
AHCY adenosylhomocysteinase 1.48648
ADK adenosine kinase 1.2018
IL2RG interleukin 2 receptor, gamma 1.17894
PNP purine nucleoside phosphorylase 1.16221
DCK deoxycytidine kinase 1.03198
BCKDK branched chain ketoacid dehydrogenase kinase 0.991065
PYGB phosphorylase, glycogen; brain 0.825768
RAG1 recombination activating gene 1 0.825768
PYGL phosphorylase, glycogen, liver 0.822488
AK2 adenylate kinase 2 0.804436
JAK3 Janus kinase 3 0.799513
PYGM phosphorylase, glycogen, muscle 0.794181
RAG2 recombination activating gene 2 0.792131
IL7R interleukin 7 receptor 0.765943
DPYS dihydropyrimidinase 0.750864
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.714811
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 0.610838
TUB tubby bipartite transcription factor 0.569941
SH2D1A SH2 domain containing 1A 0.554791
CD3D CD3d molecule, delta (CD3-TCR complex) 0.529222
GBA glucosidase, beta, acid 0.526132
SBDS Shwachman-Bodian-Diamond syndrome 0.49274
NT5E 5'-nucleotidase, ecto (CD73) 0.467306
IL2 interleukin 2 0.430768
CASQ2 calsequestrin 2 (cardiac muscle) 0.406051
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.393374
APRT adenine phosphoribosyltransferase 0.385193
LMO2 LIM domain only 2 (rhombotin-like 1) 0.371477
ADSL adenylosuccinate lyase 0.324458
CD34 CD34 molecule 0.316819
IDS iduronate 2-sulfatase 0.281153
RRM1 ribonucleotide reductase M1 0.251366
CD4 CD4 molecule 0.218715
HLA-C major histocompatibility complex, class I, C 0.211934
OAT ornithine aminotransferase 0.182375
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.162306