adenylate cyclase-modulating G protein-coupled receptor signaling pathway Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP (cAMP). (Gene Ontology, GO_0007188)
External Link http://amigo.geneontology.org/amigo/term/GO_0007188
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Genes

164 genes participating in the adenylate cyclase-modulating G protein-coupled receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADCY1 adenylate cyclase 1 (brain)
ADCY2 adenylate cyclase 2 (brain)
ADCY3 adenylate cyclase 3
ADCY4 adenylate cyclase 4
ADCY5 adenylate cyclase 5
ADCY6 adenylate cyclase 6
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8 (brain)
ADCY9 adenylate cyclase 9
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADGRB1 adhesion G protein-coupled receptor B1
ADGRB2 adhesion G protein-coupled receptor B2
ADGRB3 adhesion G protein-coupled receptor B3
ADGRD1 adhesion G protein-coupled receptor D1
ADGRD2 adhesion G protein-coupled receptor D2
ADGRE1 adhesion G protein-coupled receptor E1
ADGRE2 adhesion G protein-coupled receptor E2
ADGRE3 adhesion G protein-coupled receptor E3
ADGRE4P adhesion G protein-coupled receptor E4, pseudogene
ADGRE5 adhesion G protein-coupled receptor E5
ADGRF1 adhesion G protein-coupled receptor F1
ADGRF2 adhesion G protein-coupled receptor F2
ADGRF3 adhesion G protein-coupled receptor F3
ADGRF4 adhesion G protein-coupled receptor F4
ADGRF5 adhesion G protein-coupled receptor F5
ADGRG1 adhesion G protein-coupled receptor G1
ADGRG2 adhesion G protein-coupled receptor G2
ADGRG3 adhesion G protein-coupled receptor G3
ADGRG4 adhesion G protein-coupled receptor G4
ADGRG5 adhesion G protein-coupled receptor G5
ADGRG6 adhesion G protein-coupled receptor G6
ADGRG7 adhesion G protein-coupled receptor G7
ADGRL1 adhesion G protein-coupled receptor L1
ADGRL2 adhesion G protein-coupled receptor L2
ADGRL3 adhesion G protein-coupled receptor L3
ADGRL4 adhesion G protein-coupled receptor L4
ADM adrenomedullin
ADM2 adrenomedullin 2
ADM5 adrenomedullin 5 (putative)
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRA2A adrenoceptor alpha 2A
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AKAP12 A kinase (PRKA) anchor protein 12
AKAP5 A kinase (PRKA) anchor protein 5
AVPR2 arginine vasopressin receptor 2
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CALCA calcitonin-related polypeptide alpha
CALCB calcitonin-related polypeptide beta
CALCR calcitonin receptor
CALCRL calcitonin receptor-like
CCR3 chemokine (C-C motif) receptor 3
CHRM2 cholinergic receptor, muscarinic 2
CNR1 cannabinoid receptor 1 (brain)
CORT cortistatin
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
DRD1 dopamine receptor D1
DRD5 dopamine receptor D5
FFAR3 free fatty acid receptor 3
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GALR2 galanin receptor 2
GALR3 galanin receptor 3
GCG glucagon
GCGR glucagon receptor
GHRH growth hormone releasing hormone
GHRHR growth hormone releasing hormone receptor
GIP gastric inhibitory polypeptide
GIPR gastric inhibitory polypeptide receptor
GLP1R glucagon-like peptide 1 receptor
GLP2R glucagon-like peptide 2 receptor
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAS GNAS complex locus
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPER1 G protein-coupled estrogen receptor 1
GPHA2 glycoprotein hormone alpha 2
GPHB5 glycoprotein hormone beta 5
GPR157 G protein-coupled receptor 157
GPR161 G protein-coupled receptor 161
GPR171 G protein-coupled receptor 171
GPR26 G protein-coupled receptor 26
GPR3 G protein-coupled receptor 3
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPR37L1 G protein-coupled receptor 37 like 1
GPR4 G protein-coupled receptor 4
GPR65 G protein-coupled receptor 65
GPR78 G protein-coupled receptor 78
GRK5 G protein-coupled receptor kinase 5
GRM8 glutamate receptor, metabotropic 8
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IAPP islet amyloid polypeptide
INSL3 insulin-like 3 (Leydig cell)
LHCGR luteinizing hormone/choriogonadotropin receptor
LPAR1 lysophosphatidic acid receptor 1
MARCO macrophage receptor with collagenous structure
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MC5R melanocortin 5 receptor
MCHR1 melanin-concentrating hormone receptor 1
MTNR1A melatonin receptor 1A
NPY1R neuropeptide Y receptor Y1
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OXER1 oxoeicosanoid (OXE) receptor 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PDE2A phosphodiesterase 2A, cGMP-stimulated
PF4 platelet factor 4
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PSAP prosaposin
PSAPL1 prosaposin-like 1 (gene/pseudogene)
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGFR prostaglandin F receptor (FP)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTH parathyroid hormone
PTH1R parathyroid hormone 1 receptor
PTH2R parathyroid hormone 2 receptor
PTHLH parathyroid hormone-like hormone
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RGS1 regulator of G-protein signaling 1
RIMS2 regulating synaptic membrane exocytosis 2
SCTR secretin receptor
TBXA2R thromboxane A2 receptor
TCP11 t-complex 11, testis-specific
TSHR thyroid stimulating hormone receptor
UCN3 urocortin 3
UTS2 urotensin 2
VIP vasoactive intestinal peptide
VIPR1 vasoactive intestinal peptide receptor 1
VIPR2 vasoactive intestinal peptide receptor 2
WASF2 WAS protein family, member 2