adhd Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-IV) (Experimental Factor Ontology, EFO_0003888)
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Genes

39 genes associated with the disease adhd in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADGRL3 adhesion G protein-coupled receptor L3
ADHD1 Attention deficit-hyperactivity disorder, susceptibility to, 1
ADRA2A adrenoceptor alpha 2A
BDNF brain-derived neurotrophic factor
CDH13 cadherin 13
COMT catechol-O-methyltransferase
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
FGF10 fibroblast growth factor 10
FLNC filamin C, gamma
GDNF glial cell derived neurotrophic factor
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HK1 hexokinase 1
HKDC1 hexokinase domain containing 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ISL1 ISL LIM homeobox 1
ITGA1 integrin, alpha 1
LIN7C lin-7 homolog C (C. elegans)
MAOA monoamine oxidase A
MAOB monoamine oxidase B
NTF3 neurotrophin 3
NXPH1 neurexophilin 1
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRKG1 protein kinase, cGMP-dependent, type I
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SNAP25 synaptosomal-associated protein, 25kDa
TCERG1L transcription elongation regulator 1-like
THRB thyroid hormone receptor, beta
TPH2 tryptophan hydroxylase 2