adherens junction Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments. (Gene Ontology, GO_0005912)
External Link http://amigo.geneontology.org/amigo/term/GO:0005912
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Genes

152 proteins localized to the adherens junction cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
ABI2 abl-interactor 2
ADD1 adducin 1 (alpha)
AFDN afadin, adherens junction formation factor
AHI1 Abelson helper integration site 1
AJAP1 adherens junctions associated protein 1
AJUBA ajuba LIM protein
ALOX15B arachidonate 15-lipoxygenase, type B
ANXA1 annexin A1
ANXA2 annexin A2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BAIAP2 BAI1-associated protein 2
BAIAP2L1 BAI1-associated protein 2-like 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CCDC85A coiled-coil domain containing 85A
CCDC85B coiled-coil domain containing 85B
CCDC85C coiled-coil domain containing 85C
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDCA3 cell division cycle associated 3
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH12 cadherin 12, type 2 (N-cadherin 2)
CDH13 cadherin 13
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDH18 cadherin 18, type 2
CDH19 cadherin 19, type 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH20 cadherin 20, type 2
CDH22 cadherin 22, type 2
CDH24 cadherin 24, type 2
CDH26 cadherin 26
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDH8 cadherin 8, type 2
CDH9 cadherin 9, type 2 (T1-cadherin)
CDHR3 cadherin-related family member 3
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CNKSR3 CNKSR family member 3
CNN3 calponin 3, acidic
CNOT12 CCR4-NOT transcription complex subunit 12
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTNND2 catenin (cadherin-associated protein), delta 2
CXADR coxsackie virus and adenovirus receptor
CYTH3 cytohesin 3
DLG1 discs, large homolog 1 (Drosophila)
DLG5 discs, large homolog 5 (Drosophila)
DLL1 delta-like 1 (Drosophila)
DSPP dentin sialophosphoprotein
EHD4 EH-domain containing 4
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
ESAM endothelial cell adhesion molecule
EZR ezrin
FAT2 FAT atypical cadherin 2
FERMT2 fermitin family member 2
FLOT1 flotillin 1
FLOT2 flotillin 2
FRMD4A FERM domain containing 4A
FRMD4B FERM domain containing 4B
FRMD5 FERM domain containing 5
FRS2 fibroblast growth factor receptor substrate 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
HMCN1 hemicentin 1
IGSF21 immunoglobin superfamily, member 21
JAG1 jagged 1
JCAD junctional cadherin 5 associated
JUP junction plakoglobin
KIFC3 kinesin family member C3
KLHL24 kelch-like family member 24
KRT18 keratin 18, type I
LDB3 LIM domain binding 3
LIMD1 LIM domains containing 1
LIN7A lin-7 homolog A (C. elegans)
LIN7B lin-7 homolog B (C. elegans)
LIN7C lin-7 homolog C (C. elegans)
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LRRC7 leucine rich repeat containing 7
MICALL1 MICAL-like 1
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
MSN moesin
MYO1E myosin IE
NDRG1 N-myc downstream regulated 1
NECTIN1 nectin cell adhesion molecule 1
NECTIN2 nectin cell adhesion molecule 2
NECTIN3 nectin cell adhesion molecule 3
NECTIN4 nectin cell adhesion molecule 4
NF2 neurofibromin 2 (merlin)
NIBAN2 niban apoptosis regulator 2
NOTCH1 notch 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PALS1 protein associated with LIN7 1, MAGUK p55 family member
PARD3 par-3 family cell polarity regulator
PARD3B par-3 family cell polarity regulator beta
PARK7 parkinson protein 7
PDLIM1 PDZ and LIM domain 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PDLIM3 PDZ and LIM domain 3
PDLIM4 PDZ and LIM domain 4
PDLIM5 PDZ and LIM domain 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PGM5 phosphoglucomutase 5
PKP1 plakophilin 1
PKP2 plakophilin 2
PKP3 plakophilin 3
PKP4 plakophilin 4
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLPP3 phospholipid phosphatase 3
POF1B premature ovarian failure, 1B
POTEF POTE ankyrin domain family, member F
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRICKLE4 prickle homolog 4 (Drosophila)
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTPRM protein tyrosine phosphatase, receptor type, M
PVR poliovirus receptor
RAB10 RAB10, member RAS oncogene family
RDX radixin
RND1 Rho family GTPase 1
S100A11 S100 calcium binding protein A11
SCRIB scribbled planar cell polarity protein
SDCBP syndecan binding protein (syntenin)
SH3BP1 SH3-domain binding protein 1
SHROOM1 shroom family member 1
SHROOM2 shroom family member 2
SHROOM3 shroom family member 3
SHROOM4 shroom family member 4
SMAD7 SMAD family member 7
SNAP23 synaptosomal-associated protein, 23kDa
SORBS1 sorbin and SH3 domain containing 1
SPTBN4 spectrin, beta, non-erythrocytic 4
STXBP6 syntaxin binding protein 6 (amisyn)
TJP1 tight junction protein 1
TLN1 talin 1
TMOD3 tropomodulin 3 (ubiquitous)
TRIM29 tripartite motif containing 29
TRPV4 transient receptor potential cation channel, subfamily V, member 4
VCL vinculin
VEGFA vascular endothelial growth factor A
WNK3 WNK lysine deficient protein kinase 3
WTIP Wilms tumor 1 interacting protein
ZYX zyxin