adiphenine-1709 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the adiphenine-1709 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADGRG2 adhesion G protein-coupled receptor G2
ADGRL1 adhesion G protein-coupled receptor L1
ADRBK2 adrenergic, beta, receptor kinase 2
AHCYL2 adenosylhomocysteinase-like 2
AK1 adenylate kinase 1
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARID3B AT rich interactive domain 3B (BRIGHT-like)
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BAHCC1 BAH domain and coiled-coil containing 1
BAIAP2 BAI1-associated protein 2
BMP4 bone morphogenetic protein 4
BOLA1 bolA family member 1
C2ORF68 chromosome 2 open reading frame 68
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBX6 chromobox homolog 6
CDK3 cyclin-dependent kinase 3
CHEK2 checkpoint kinase 2
CHML choroideremia-like (Rab escort protein 2)
COMMD4 COMM domain containing 4
CORO1B coronin, actin binding protein, 1B
CRLF1 cytokine receptor-like factor 1
CSPP1 centrosome and spindle pole associated protein 1
CUL4B cullin 4B
CYHR1 cysteine/histidine-rich 1
DGAT1 diacylglycerol O-acyltransferase 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
E2F4 E2F transcription factor 4, p107/p130-binding
EPHA2 EPH receptor A2
ERAP1 endoplasmic reticulum aminopeptidase 1
FADS3 fatty acid desaturase 3
FBXO31 F-box protein 31
FKBP10 FK506 binding protein 10, 65 kDa
FLOT1 flotillin 1
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli)
GAMT guanidinoacetate N-methyltransferase
GMPR guanosine monophosphate reductase
GOSR2 golgi SNAP receptor complex member 2
GPR137 G protein-coupled receptor 137
HDAC11 histone deacetylase 11
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HLA-J major histocompatibility complex, class I, J (pseudogene)
IDUA iduronidase, alpha-L-
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INADL InaD-like (Drosophila)
ING1 inhibitor of growth family, member 1
JAG1 jagged 1
KDM4A lysine (K)-specific demethylase 4A
KIAA0319L KIAA0319-like
KPNA5 karyopherin alpha 5 (importin alpha 6)
LMF1 lipase maturation factor 1
LMNB1 lamin B1
MAPK7 mitogen-activated protein kinase 7
MID1 midline 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NYNRIN NYN domain and retroviral integrase containing
PDLIM7 PDZ and LIM domain 7 (enigma)
PHC1 polyhomeotic homolog 1 (Drosophila)
PLK4 polo-like kinase 4
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
POU4F1 POU class 4 homeobox 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RABL3 RAB, member of RAS oncogene family-like 3
RAD54L2 RAD54-like 2 (S. cerevisiae)
RARA retinoic acid receptor, alpha
RARS arginyl-tRNA synthetase
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RPL10L ribosomal protein L10-like
S100A11 S100 calcium binding protein A11
SFXN3 sideroflexin 3
SIRT3 sirtuin 3
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SNHG3 small nucleolar RNA host gene 3
SNX1 sorting nexin 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT5B signal transducer and activator of transcription 5B
STK16 serine/threonine kinase 16
STX7 syntaxin 7
TBC1D17 TBC1 domain family, member 17
TSPAN3 tetraspanin 3
TTLL1 tubulin tyrosine ligase-like family member 1
UBOX5 U-box domain containing 5
USP36 ubiquitin specific peptidase 36
WDR45 WD repeat domain 45
WDR59 WD repeat domain 59
ZBTB1 zinc finger and BTB domain containing 1
ZBTB44 zinc finger and BTB domain containing 44
ZBTB48 zinc finger and BTB domain containing 48
ZER1 zyg-11 related, cell cycle regulator
ZNF324 zinc finger protein 324
ZNF428 zinc finger protein 428
ZNF75D zinc finger protein 75D
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BATF basic leucine zipper transcription factor, ATF-like
C5 complement component 5
CEPT1 choline/ethanolamine phosphotransferase 1
CHKB choline kinase beta
CLCN5 chloride channel, voltage-sensitive 5
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CRYBG3 beta-gamma crystallin domain containing 3
CSTA cystatin A (stefin A)
CUL9 cullin 9
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF16 DDB1 and CUL4 associated factor 16
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EFCAB2 EF-hand calcium binding domain 2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
FAM53B family with sequence similarity 53, member B
FBXW12 F-box and WD repeat domain containing 12
FCF1 FCF1 rRNA-processing protein
FER fer (fps/fes related) tyrosine kinase
FICD FIC domain containing
FLJ22184
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FNDC3B fibronectin type III domain containing 3B
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HAUS2 HAUS augmin-like complex, subunit 2
HELLS helicase, lymphoid-specific
HIST1H2AG histone cluster 1, H2ag
HIST1H2AJ histone cluster 1, H2aj
HIST1H4C histone cluster 1, H4c
HMOX1 heme oxygenase 1
INCENP inner centromere protein antigens 135/155kDa
INPPL1 inositol polyphosphate phosphatase-like 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIAA0355 KIAA0355
LMBR1L limb development membrane protein 1-like
LOC100287590 uncharacterized LOC100287590
LOC730101 uncharacterized LOC730101
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGT1 magnesium transporter 1
MANSC1 MANSC domain containing 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MED18 mediator complex subunit 18
METTL16 methyltransferase like 16
MFSD11 major facilitator superfamily domain containing 11
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MITF microphthalmia-associated transcription factor
NDE1 nudE neurodevelopment protein 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NPIPB15 nuclear pore complex interacting protein family, member B15
NR1D2 nuclear receptor subfamily 1, group D, member 2
P3H1 prolyl 3-hydroxylase 1
PARD6A par-6 family cell polarity regulator alpha
PLA2G3 phospholipase A2, group III
POLH polymerase (DNA directed), eta
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTER phosphotriesterase related
PTK6 protein tyrosine kinase 6
RIBC2 RIB43A domain with coiled-coils 2
RNF2 ring finger protein 2
SIX1 SIX homeobox 1
SLC16A6 solute carrier family 16, member 6
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC38A1 solute carrier family 38, member 1
SMAD5 SMAD family member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOX12 SRY (sex determining region Y)-box 12
SPIN1 spindlin 1
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYMPK symplekin
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIPRL TOR signaling pathway regulator
TMEM104 transmembrane protein 104
TMEM159 transmembrane protein 159
TMEM260 transmembrane protein 260
TMEM62 transmembrane protein 62
TRIM66 tripartite motif containing 66
UGCG UDP-glucose ceramide glucosyltransferase
USB1 U6 snRNA biogenesis 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR76 WD repeat domain 76
WWC2 WW and C2 domain containing 2
ZBTB22 zinc finger and BTB domain containing 22
ZBTB38 zinc finger and BTB domain containing 38
ZNF205 zinc finger protein 205
ZNF331 zinc finger protein 331
ZNF573 zinc finger protein 573