adiphenine-1872 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the adiphenine-1872 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACTA2 actin, alpha 2, smooth muscle, aorta
ADK adenosine kinase
ANKRD12 ankyrin repeat domain 12
ANXA3 annexin A3
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARF6 ADP-ribosylation factor 6
ATP11A ATPase, class VI, type 11A
BBS4 Bardet-Biedl syndrome 4
BICD2 bicaudal D homolog 2 (Drosophila)
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
C22ORF29 chromosome 22 open reading frame 29
CD59 CD59 molecule, complement regulatory protein
CDK13 cyclin-dependent kinase 13
CDR2L cerebellar degeneration-related protein 2-like
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COPS8 COP9 signalosome subunit 8
CREM cAMP responsive element modulator
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTBP2 C-terminal binding protein 2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYSLTR1 cysteinyl leukotriene receptor 1
DGAT1 diacylglycerol O-acyltransferase 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHBP1 EH domain binding protein 1
EIF1 eukaryotic translation initiation factor 1
FUS FUS RNA binding protein
GGCX gamma-glutamyl carboxylase
GK glycerol kinase
ICK intestinal cell (MAK-like) kinase
ING1 inhibitor of growth family, member 1
ING4 inhibitor of growth family, member 4
JAK2 Janus kinase 2
KIAA1107 KIAA1107
KRCC1 lysine-rich coiled-coil 1
KRIT1 KRIT1, ankyrin repeat containing
LACTB2 lactamase, beta 2
LAMP1 lysosomal-associated membrane protein 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MCPH1 microcephalin 1
MDFIC MyoD family inhibitor domain containing
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MYB v-myb avian myeloblastosis viral oncogene homolog
N4BP2L2 NEDD4 binding protein 2-like 2
NCOA2 nuclear receptor coactivator 2
NDE1 nudE neurodevelopment protein 1
NFRKB nuclear factor related to kappaB binding protein
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OXR1 oxidation resistance 1
PAQR3 progestin and adipoQ receptor family member III
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PEX26 peroxisomal biogenesis factor 26
PHACTR1 phosphatase and actin regulator 1
PIAS4 protein inhibitor of activated STAT, 4
PIDD1 p53-induced death domain protein 1
PLAGL1 pleiomorphic adenoma gene-like 1
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PSD3 pleckstrin and Sec7 domain containing 3
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RAD17 RAD17 homolog (S. pombe)
RBM5 RNA binding motif protein 5
RHOQ ras homolog family member Q
RNF121 ring finger protein 121
RPS2 ribosomal protein S2
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SIDT2 SID1 transmembrane family, member 2
SLC25A44 solute carrier family 25, member 44
SLC35E3 solute carrier family 35, member E3
SLC38A6 solute carrier family 38, member 6
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLFN12 schlafen family member 12
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSH3 slingshot protein phosphatase 3
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STOML1 stomatin (EPB72)-like 1
TFR2 transferrin receptor 2
TSPAN13 tetraspanin 13
UBE2B ubiquitin-conjugating enzyme E2B
UBOX5 U-box domain containing 5
UGCG UDP-glucose ceramide glucosyltransferase
WBP4 WW domain binding protein 4
WDHD1 WD repeat and HMG-box DNA binding protein 1
YTHDC1 YTH domain containing 1
ZBTB35 zinc finger and BTB domain containing 35
ZBTB40 zinc finger and BTB domain containing 40
ZC2HC1A zinc finger, C2HC-type containing 1A
ZHX3 zinc fingers and homeoboxes 3
ZNF280D zinc finger protein 280D
ZNF324 zinc finger protein 324
ZNF573 zinc finger protein 573
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACPP acid phosphatase, prostate
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AGO4 argonaute RISC catalytic component 4
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALPK1 alpha-kinase 1
ARMC7 armadillo repeat containing 7
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BPHL biphenyl hydrolase-like (serine hydrolase)
BTBD2 BTB (POZ) domain containing 2
C17ORF70 chromosome 17 open reading frame 70
C3 complement component 3
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC130 coiled-coil domain containing 130
CCDC85C coiled-coil domain containing 85C
CCDC88C coiled-coil domain containing 88C
CD70 CD70 molecule
CEP170B centrosomal protein 170B
CLCF1 cardiotrophin-like cytokine factor 1
CPNE7 copine VII
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ENO3 enolase 3 (beta, muscle)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FAM184A family with sequence similarity 184, member A
FBXL7 F-box and leucine-rich repeat protein 7
GALK1 galactokinase 1
GIPC1 GIPC PDZ domain containing family, member 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR85 G protein-coupled receptor 85
GSDMD gasdermin D
GSPT2 G1 to S phase transition 2
GTF2IRD1 GTF2I repeat domain containing 1
GTPBP6 GTP binding protein 6 (putative)
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H2AJ histone cluster 1, H2aj
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INO80D INO80 complex subunit D
KDM8 lysine (K)-specific demethylase 8
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LPAR4 lysophosphatidic acid receptor 4
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP5 low density lipoprotein receptor-related protein 5
LY6E lymphocyte antigen 6 complex, locus E
MAGEF1 melanoma antigen family F1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NPFFR1 neuropeptide FF receptor 1
OCEL1 occludin/ELL domain containing 1
ODF2 outer dense fiber of sperm tails 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCSK7 proprotein convertase subtilisin/kexin type 7
PDZD7 PDZ domain containing 7
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PROCR protein C receptor, endothelial
PRR7 proline rich 7 (synaptic)
PYGB phosphorylase, glycogen; brain
RAB17 RAB17, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RIN1 Ras and Rab interactor 1
RNF126P1 ring finger protein 126 pseudogene 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCGB2A2 secretoglobin, family 2A, member 2
SFMBT1 Scm-like with four mbt domains 1
SHPK sedoheptulokinase
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPAG4 sperm associated antigen 4
STEAP3 STEAP family member 3, metalloreductase
STX1A syntaxin 1A (brain)
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYCP2 synaptonemal complex protein 2
TESK1 testis-specific kinase 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM120B transmembrane protein 120B
TMEM140 transmembrane protein 140
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM26 tripartite motif containing 26
TTPAL tocopherol (alpha) transfer protein-like
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UNC93B1 unc-93 homolog B1 (C. elegans)
USP19 ubiquitin specific peptidase 19
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
ZBTB25 zinc finger and BTB domain containing 25
ZC3H3 zinc finger CCCH-type containing 3
ZNF197 zinc finger protein 197
ZNF32 zinc finger protein 32
ZNF480 zinc finger protein 480
ZNF574 zinc finger protein 574
ZNF629 zinc finger protein 629
ZNF675 zinc finger protein 675
ZNF747 zinc finger protein 747