adipiodone-6490 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the adipiodone-6490 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM12 ADAM metallopeptidase domain 12
ADAM15 ADAM metallopeptidase domain 15
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ALOX5 arachidonate 5-lipoxygenase
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APC2 adenomatosis polyposis coli 2
AQP3 aquaporin 3 (Gill blood group)
AQP7 aquaporin 7
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARTN artemin
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAPN9 calpain 9
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCKAR cholecystokinin A receptor
CCRL2 chemokine (C-C motif) receptor-like 2
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLCA1 chloride channel accessory 1
CLDN1 claudin 1
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL6A1 collagen, type VI, alpha 1
COL9A3 collagen, type IX, alpha 3
CSPP1 centrosome and spindle pole associated protein 1
DCN decorin
DMPK dystrophia myotonica-protein kinase
DOK4 docking protein 4
DOPEY2 dopey family member 2
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EN1 engrailed homeobox 1
FAM214B family with sequence similarity 214, member B
FDPS farnesyl diphosphate synthase
FGF17 fibroblast growth factor 17
FGFR1 fibroblast growth factor receptor 1
FKBP10 FK506 binding protein 10, 65 kDa
GFAP glial fibrillary acidic protein
GMPR guanosine monophosphate reductase
GSTA3 glutathione S-transferase alpha 3
GSTCD glutathione S-transferase, C-terminal domain containing
HAP1 huntingtin-associated protein 1
HCK HCK proto-oncogene, Src family tyrosine kinase
HOXB3 homeobox B3
HPX hemopexin
ICOSLG inducible T-cell co-stimulator ligand
IL16 interleukin 16
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KIF25-AS1 KIF25 antisense RNA 1
KRT12 keratin 12, type I
MST1 macrophage stimulating 1
MYH7 myosin, heavy chain 7, cardiac muscle, beta
N4BP2L1 NEDD4 binding protein 2-like 1
NCOA2 nuclear receptor coactivator 2
NELL2 NEL-like 2 (chicken)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NREP neuronal regeneration related protein
PAX8 paired box 8
PEAK1 pseudopodium-enriched atypical kinase 1
PLCL2 phospholipase C-like 2
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP5C protein phosphatase 5, catalytic subunit
PSD3 pleckstrin and Sec7 domain containing 3
PTGDR2 prostaglandin D2 receptor 2
PTGFR prostaglandin F receptor (FP)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
QPCTL glutaminyl-peptide cyclotransferase-like
RARB retinoic acid receptor, beta
RBM12B-AS1 RBM12B antisense RNA 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS20 regulator of G-protein signaling 20
RIN3 Ras and Rab interactor 3
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RUNX1 runt-related transcription factor 1
SAMD9 sterile alpha motif domain containing 9
SCN11A sodium channel, voltage gated, type XI alpha subunit
SHOX2 short stature homeobox 2
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMIM14 small integral membrane protein 14
SOX21 SRY (sex determining region Y)-box 21
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSX7 synovial sarcoma, X breakpoint 7
SZT2 seizure threshold 2 homolog (mouse)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D17 TBC1 domain family, member 17
USB1 U6 snRNA biogenesis 1
ZDHHC8P1 zinc finger, DHHC-type containing 8 pseudogene 1
ZFP64 ZFP64 zinc finger protein
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF75D zinc finger protein 75D

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTL8 actin-like 8
AKAP12 A kinase (PRKA) anchor protein 12
AKTIP AKT interacting protein
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARMCX5 armadillo repeat containing, X-linked 5
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BCAS1 breast carcinoma amplified sequence 1
BEX4 brain expressed, X-linked 4
BFSP1 beaded filament structural protein 1, filensin
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C5AR2 complement component 5a receptor 2
CASD1 CAS1 domain containing 1
CD82 CD82 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDND1 claudin domain containing 1
COCH cochlin
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRYL1 crystallin, lambda 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DBR1 debranching RNA lariats 1
DDIT3 DNA-damage-inducible transcript 3
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
FAM155A family with sequence similarity 155, member A
FAM169A family with sequence similarity 169, member A
FAM188A family with sequence similarity 188, member A
FBXO22 F-box protein 22
FSD1 fibronectin type III and SPRY domain containing 1
FUZ fuzzy planar cell polarity protein
FZD3 frizzled class receptor 3
GRTP1 growth hormone regulated TBC protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSPA4L heat shock 70kDa protein 4-like
HYI hydroxypyruvate isomerase (putative)
IMPAD1 inositol monophosphatase domain containing 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD3 potassium channel tetramerization domain containing 3
KIF13B kinesin family member 13B
KIFAP3 kinesin-associated protein 3
KLF3 Kruppel-like factor 3 (basic)
LIME1 Lck interacting transmembrane adaptor 1
MAGEF1 melanoma antigen family F1
MANBA mannosidase, beta A, lysosomal
MANEA mannosidase, endo-alpha
MBTD1 mbt domain containing 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUC3B mucin 3B, cell surface associated
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NKAIN1 Na+/K+ transporting ATPase interacting 1
NOL12 nucleolar protein 12
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIKFYVE phosphoinositide kinase, FYVE finger containing
PISD phosphatidylserine decarboxylase
PLD2 phospholipase D2
RBL1 retinoblastoma-like 1
RIN2 Ras and Rab interactor 2
RLF rearranged L-myc fusion
RNF122 ring finger protein 122
RNF170 ring finger protein 170
RPL10L ribosomal protein L10-like
SAV1 salvador family WW domain containing protein 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SETD1A SET domain containing 1A
SGK1 serum/glucocorticoid regulated kinase 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SH2B3 SH2B adaptor protein 3
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC35F5 solute carrier family 35, member F5
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SRPX sushi-repeat containing protein, X-linked
STEAP3 STEAP family member 3, metalloreductase
SYCP2 synaptonemal complex protein 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TET3 tet methylcytosine dioxygenase 3
THUMPD2 THUMP domain containing 2
TMEM104 transmembrane protein 104
TMEM53 transmembrane protein 53
TMEM62 transmembrane protein 62
TRAPPC2 trafficking protein particle complex 2
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSPAN2 tetraspanin 2
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZMAT5 zinc finger, matrin-type 5
ZNF226 zinc finger protein 226
ZNF254 zinc finger protein 254
ZNF280D zinc finger protein 280D
ZNF408 zinc finger protein 408
ZNF574 zinc finger protein 574
ZNF586 zinc finger protein 586
ZNF675 zinc finger protein 675