adrb2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description adrenoceptor beta 2, surface|This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 154)
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Genes

23 genes co-occuring with the biological term adrb2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADRA1A adrenoceptor alpha 1A
ADRA2A adrenoceptor alpha 2A
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
CCL5 chemokine (C-C motif) ligand 5
CHRM3 cholinergic receptor, muscarinic 3
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FTO fat mass and obesity associated
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
IL10 interleukin 10
KIF21A kinesin family member 21A
LEPR leptin receptor
NMU neuromedin U
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
NPY neuropeptide Y
PCNT pericentrin
RRP1B ribosomal RNA processing 1B
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4