adrenosterone-5045 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the adrenosterone-5045 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ADARB1 adenosine deaminase, RNA-specific, B1
ADRBK1 adrenergic, beta, receptor kinase 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANGEL2 angel homolog 2 (Drosophila)
APOC4 apolipoprotein C-IV
ARHGAP35 Rho GTPase activating protein 35
ARMC4 armadillo repeat containing 4
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BBC3 BCL2 binding component 3
BICD1 bicaudal D homolog 1 (Drosophila)
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CADM3 cell adhesion molecule 3
CD4 CD4 molecule
CD8B CD8b molecule
CDX1 caudal type homeobox 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CNGB3 cyclic nucleotide gated channel beta 3
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DCTN1 dynactin 1
DFNB31 deafness, autosomal recessive 31
DGKA diacylglycerol kinase, alpha 80kDa
DSCR4 Down syndrome critical region 4
DTNA dystrobrevin, alpha
DUSP1 dual specificity phosphatase 1
EFNB3 ephrin-B3
EGFR epidermal growth factor receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF21 fibroblast growth factor 21
FGF4 fibroblast growth factor 4
FLCN folliculin
GAL galanin/GMAP prepropeptide
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GOLGA8A golgin A8 family, member A
GPATCH4 G patch domain containing 4
GRAMD1C GRAM domain containing 1C
GREB1L growth regulation by estrogen in breast cancer-like
GRM7 glutamate receptor, metabotropic 7
HEATR6 HEAT repeat containing 6
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IDI2-AS1 IDI2 antisense RNA 1
IFNA14 interferon, alpha 14
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL18R1 interleukin 18 receptor 1
ITGB4 integrin, beta 4
KDM4B lysine (K)-specific demethylase 4B
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHL22 kelch-like family member 22
KLK1 kallikrein 1
KRT86 keratin 86, type II
LIMD2 LIM domain containing 2
LY86 lymphocyte antigen 86
MAPK11 mitogen-activated protein kinase 11
MEF2D myocyte enhancer factor 2D
MOGAT2 monoacylglycerol O-acyltransferase 2
MTCP1 mature T-cell proliferation 1
NCOA2 nuclear receptor coactivator 2
NOP16 NOP16 nucleolar protein
NRP2 neuropilin 2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
ORC5 origin recognition complex, subunit 5
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PELI2 pellino E3 ubiquitin protein ligase family member 2
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHLDB1 pleckstrin homology-like domain, family B, member 1
PNLIPRP2 pancreatic lipase-related protein 2
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTCRA pre T-cell antigen receptor alpha
RAD52 RAD52 homolog (S. cerevisiae)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
REEP2 receptor accessory protein 2
RNF126P1 ring finger protein 126 pseudogene 1
RPL35A ribosomal protein L35a
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNX1 runt-related transcription factor 1
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SERHL2 serine hydrolase-like 2
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
TBC1D22A TBC1 domain family, member 22A
TBX5 T-box 5
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TCP11L1 t-complex 11, testis-specific-like 1
TET3 tet methylcytosine dioxygenase 3
TRAF3IP3 TRAF3 interacting protein 3
USP20 ubiquitin specific peptidase 20
WNK1 WNK lysine deficient protein kinase 1
ZBBX zinc finger, B-box domain containing
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA10 annexin A10
ASB13 ankyrin repeat and SOCS box containing 13
ATAD5 ATPase family, AAA domain containing 5
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BFSP1 beaded filament structural protein 1, filensin
C14ORF93 chromosome 14 open reading frame 93
C22ORF46 chromosome 22 open reading frame 46
CA11 carbonic anhydrase XI
CADPS2 Ca++-dependent secretion activator 2
CAPN5 calpain 5
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX7 chromobox homolog 7
CHKB choline kinase beta
CINP cyclin-dependent kinase 2 interacting protein
CLDN1 claudin 1
CLIC3 chloride intracellular channel 3
CNN1 calponin 1, basic, smooth muscle
CORT cortistatin
CREB5 cAMP responsive element binding protein 5
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DTWD1 DTW domain containing 1
EFCAB2 EF-hand calcium binding domain 2
EGF epidermal growth factor
ERAP2 endoplasmic reticulum aminopeptidase 2
FGF23 fibroblast growth factor 23
GALT galactose-1-phosphate uridylyltransferase
GAREM GRB2 associated, regulator of MAPK1
GMEB1 glucocorticoid modulatory element binding protein 1
GPC3 glypican 3
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
H2AFJ H2A histone family, member J
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IFT54 intraflagellar transport 54
IFT74 intraflagellar transport 74
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL6 interleukin 6
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0753 KIAA0753
KLC2 kinesin light chain 2
KLF13 Kruppel-like factor 13
KLHL28 kelch-like family member 28
LATS1 large tumor suppressor kinase 1
LMO7 LIM domain 7
MAPK12 mitogen-activated protein kinase 12
MED31 mediator complex subunit 31
MON1B MON1 secretory trafficking family member B
MYLIP myosin regulatory light chain interacting protein
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NINJ1 ninjurin 1
ODF2 outer dense fiber of sperm tails 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSBP2 oxysterol binding protein 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PRICKLE3 prickle homolog 3 (Drosophila)
PRSS53 protease, serine, 53
PTK7 protein tyrosine kinase 7 (inactive)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGCC regulator of cell cycle
RGS19 regulator of G-protein signaling 19
RIN1 Ras and Rab interactor 1
RNF39 ring finger protein 39
SCARA3 scavenger receptor class A, member 3
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35F6 solute carrier family 35, member F6
SLC46A3 solute carrier family 46, member 3
SNHG20 small nucleolar RNA host gene 20
SNTA1 syntrophin, alpha 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STBD1 starch binding domain 1
STEAP4 STEAP family member 4
SUGCT succinyl-CoA:glutarate-CoA transferase
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TEAD3 TEA domain family member 3
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMC5 transmembrane channel-like 5
TMEM209 transmembrane protein 209
TMEM53 transmembrane protein 53
TMOD3 tropomodulin 3 (ubiquitous)
TRABD TraB domain containing
TUBA3C tubulin, alpha 3c
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
VASH2 vasohibin 2
ZBTB6 zinc finger and BTB domain containing 6
ZFHX3 zinc finger homeobox 3
ZNF253 zinc finger protein 253
ZNF37BP zinc finger protein 37B, pseudogene
ZNF480 zinc finger protein 480
ZNF668 zinc finger protein 668
ZNF813 zinc finger protein 813
ZNF862 zinc finger protein 862